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Articles Related to Sepsis

ED Patients with Shock have only Few Clinical Characteristics Related to Etiology

The aim of this study is to describe clinical variables and comorbidities in patients with shock, at arrival to the emergency department, and evaluate the diagnostic validity for different shock etiologies. This was a retrospective cohort study with tertiary analysis of data previously published in two other studies. The study population was all patients with shock, arriving to the emergency department at Odense University Hospital between 2000 and 2011. Shock was defined as systolic blood pressure ≤100mmHg and one or more organ failures. Patients were grouped according to discharge diagnoses and this method was manually validated through patient records. The diagnostic value of 26 clinical variables and 10 comorbidities were described and tested.
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New Insight for Early Diagnosis of Neonatal Sepsis

Mean platelet volume MPV that is included in CBC, will be larger with platelet destruction problems as in Neonatal sepsis NS or when the body is producing increased numbers of platelets. Also, NS is associated with increased production of reactive oxygen species that will lead to consumption of specific antioxidant molecules like uric acid. The aim of the work: to determine the role of MPV and uric acid levels in the early diagnosis of NS.
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The Roles of Procalcitonin, C-Reactive Protein and Erythrocyte Sedimentation Rate in Predicting Bacteremia

The early differentiation between infectious and non-infectious sepsis remains a challenge due to the lack of a reliable, ready available and quick biomarker of bacterial sepsis. This study aims to determine the diagnostic accuracies of procalcitonin (PCT), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) as individual and combined predictors of bacterial sepsis, when compared to the gold standard microbiological cultures
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Disseminated Cutaneous Mycobacterium Chelonae Infection in a 9.5-Year-Old Girl with Diabetes

Mycobacterium chelonae is a fast growing mycobacteria that mainly causes localized cutaneous infections. Disseminated cutaneous infections are quite exclusively seen in immunosuppressed individuals. We present a case of disseminated cutaneous infection in a young diabetic patient.
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Procalcitonin versus C-Reactive Protein in Neonatal Sepsis

Urinary tract infection (UTI) is the most common serious bacterial infection in febrile children younger than 3 months, with reported rates ranging from 5% to 20% depending on different series. Neonates and infants up to age 2 months who have pyelonephritis usually do not have symptoms localized to the urinary tract.
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Thrombotic Microangiopathy Associated with Intravenous Injection Of Opana Er®: University Medical Center Case Series.

In response to the rapidly rising intravenous opioid abuse epidemic, the United States Food and Drug Administration is currently promoting the development of prescription opioid tablets that are specifically formulated to deter abuse. Opana ER® (Endo Pharmaceuticals) recently underwent reformulation to include a crush-resistant coating. Only recently described, illicit intravenous injection of reformulated Opana ER® is associated with a distinctive clinical syndrome of thrombotic microangiopathy.
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MAPK Pathway in Skeletal Muscle Diseases

Mitogen-Activated Protein Kinase (MAPK) pathway is a signal transduction pathway that functions in a wide range of physiological and pathophysiological cellular events including cell proliferation, differentiation, apoptosis, migration, inflammation, metabolic disorders and diseases.
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Editorial Board Members Related to Sepsis

Henrique Serezani

Assistant Professor
Department of Microbiology and Immunology
Indiana University
United States

MICHAEL FRASS

Professor of Medicine
Specialist in Internal Medicine, Homeopathy
University of Vienna
Austria

MICHAEL P. SHERMAN

Professor Emeritus
Department of Child Health
Division of Neonatology
University of California-Davis School of Medicine
United States

Carmelo Romeo

Pediatric Surgeon
Department of Pediatric, Gynecological, Microbiological and Biomedical Sceinces
University of Messina
Italy

Luis Ulloa

Associate Professor
Department of Surgery
Rutgers New Jersey Medical School
United States

Ziad N. AL-Dwairi

Professor
Fixed and Removable Prosthodontics and Implant Dentistry
Jordan University of Science and Technology
Jordan
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