Articles Related to Simman R
Integra was first used to replace the dermis in third-degree burns to minimize contraction and scarring, its usage had led to better functional and aesthetic results. It acts as a network for dermal reconstruction. Its usage had expanded in trauma and soft tissue defects resulting after cancer excision and other defects with tendons and bone exposure.
Warfarin is the most frequently prescribed oral anticoagulant in the United States. Its indications range from treatment of deep venous thrombosis and pulmonary emboli to the prophylaxis and treatment of thromboembolic conditions associated with atrial fibrillation and cardiac valve replacement. While bleeding is the most commonly encountered complication warfarin induced skin necrosis (WISN) can be a rare complication. Extensive skin and deeper tissue necrosis may be encountered requiring multiple surgical debridement and reconstructive procedures along with the medical management.