Articles Related to Solvent
Formulation and In-vitro Characterization of Fluoxetine Hydrochloride Loaded Fast Dissolving Oral Film Using HPMC 15CPS and HPMC K4M
Fluoxetine Hydrochloride (FH), a selective serotonin reuptake inhibitor (SSRI) is a drug of choice in depression, obsessive-compulsive disorder (OCD), bulimia nervosa, etc. Though tablet, capsules, oral solution, or syrup are currently available conventional dosage form of FH, modified or immediate-release formulations for fast onset of action is of utmost importance.
Production and Stabilization of Biomass Derived Bio-Oil using Non-Catalytic Pyrolysis Approach
Considering high demand of exploring clean and sustainable source of energy worldwide, biomass derived green bioenergy has tremendous potential. Amongst all possible ways of biomass processing to derive bio-fuels, the biomass pyrolysis is highly preferred thermochemical process that converts the biomass to bio-oil. In our present work, the noncatalytic pyrolysis of ligno-cellulosic biomass samples (sawdust, rice straw and cotton stalk) was successfully carried out using in-house developed fixed bed pyrolytic reactor.
Reduction of Bitterness and Enhancing Palatability of Cetirizine Oral Liquid Dosage Forms by Cyclodextrins
The aim of this manuscript is to study cyclodextrins (CDs) as a potential excipient to suppress bitterness and enhance palatability of pediatric liquid preparations for Cetirizine, an extremely bitter drug. Natural α, β and γ CDs; and β CD derivatives such as hydroxyl propyl (HP), randomly methylated (RM) and sulfobutyl ether (SBE) β-CDs were screened in different molar ratios of 1:1, 1:2 and 1:3 for their inhibition of the extremely bitter taste of Cetirizine using the human gustatory sensation test.
Liposphere: A Versatile Controlled Release Carrier for Hydrophobic Drugs
Researchers have been inventing new drugs since time immemorial. Of late it is established that the development of new drugs alone is not sufficient to ensure progress in drug therapy. The missing link is a potential strategy.It involves the apt selection of drug carrier systems.
Topical Delivery System for Phytochemicals: Capsaicin and Capsicum Tincture
Capsaicin, an active ingredient of Capsicum fruit, is currently undergoing “revival” in the clinical management of pain. However, the choice of its formulation is rather limited to the use of “old-fashioned” tinctures and recently the patches. In an attempt to improve the therapeutic outcome and develop its skin-friendly formulation, we prepared the vesicle-based drug delivery system with capsaicin.
Development of a Stability Indicating UPLC-MS/MS Method for Rapid and Reliable Determination of Fenofibrate in Marketed Product (Lypanthyl® 200M) and Human Plasma
A reliable, fast, sensitive and selective Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) method has been developed and validated for the determination of fenofibrate in marketed product (Lipanthyl) and human plasma. The chromatographic separation was performed on a reversed-phase Acquity®BEH C18 column (1.7 μm particle size, 50 mm x 2.1 mm ID) with an isocratic elution profile and mobile phase consisting of methanol and water (80:20, %, v/v). To achieve optimum chromatographic condition the influence of mobile phase composition and flow rate was investigated. The total chromatographic analysis time was as short as 2 min.
Sustainable Nanomaterials: A Greener Future Avenue?
The field of nanoscience has experienced a staggering number of advances in recent years with regards to a wide range of disciplines including physics, chemistry, materials science, biology and medicine.
