Articles Related to Subfertility
Does the Level of Chlamydia Serology Titre Correlate to the Degree of Tubal Disease at Laparoscopy? A Retrospective Controlled Study
In order to detect if there is any correlation between the level of total and specific Chlamydia serology titre and the degree of tubal disease at laparoscopy in sub fertile women and to compare the results with a control group. A retrospective controlled clinical study was conducted in a hospital setting (both inpatient and outpatient clinic). A total of hundred and twenty two sub fertile women who underwent laparoscopy/tubal surgery in the period between January 2011-January 2014 were included. This included 40 women with positive Chlamydia Trachomatis specific titre (group 1), 40 with positive Chlamydia serology total titre only (group 2) and 42 women with negative Chlamydia serology titre (control group). Chlamydia serology titre was measured by ELISA. The differentiated Chlamydia specific titres were measured using Microscopic Immunofluorescence Assay (MIF) to determine the immunity status. The Chlamydia Trachomatis IgG titres were classified for the purpose of the study into normal (<1/16), Mild (1/16), Moderate (1/32), and severe (>=1/64). Laparoscopic grading of tubal disease was performed into grades 1-3 according to the severity of the tubal damage which was compared to the Chlamydia titre. Pearson`s correlation test was used as a descriptive measure.