Articles Related to Syndrome

The participants underwent assessments across all Theory of Mind (ToM) tasks. All individuals were native speakers, comprising 74 from Iran and 66 from Sweden, aged 6-12, and included those with autism spectrum disorder, Down syndrome, and typical development. We conclude that children’s behavior serves as a scale for social and thought problem assessments, evaluated based on teachers' and parents’ scores.

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With the progress of society, the development of science and technology, and the popularization of digitalization, the number of patients seeking treatment for "hand numbness" in the outpatient department of rehabilitation medicine is increasing day by day, and it shows a younger age, even some teenagers; Most of them are diagnosed as cervical spondylosis, but according to the treatment of cervical spondylosis, the effect is not good, sometimes prolonged and not cured, which has different degrees of impact on the work and life of patients, and even affects the physical and mental health of patient

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Alport Syndrome is a hereditary condition that affects the collagen in the basement membrane and is characterized by microscopic hematuria, sensorineural hearing loss, increasing renal dysfunction, and ocular abnormalities. It is more common between the ages of 20 and 30. Men and women are equally affected. However, the prognosis of men is worse than women due to renal failure. The purpose of this study is to evaluate the demographic and clinical findings of patients with Alport Syndrome in our center

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Eczema herpeticum (EH) is a skin infection caused by the herpes simplex virus (HSV) that occurs in individuals with atopic dermatitis. It is characterized by the sudden appearance of vesicles and erosions with crusts over areas affected by eczema. EH can range from mild and self-limiting in healthy adults to life-threatening in children, infants, and immunocompromised patients. Early treatment with antiviral therapy is crucial in preventing complications and mortality. EH is primarily caused by a superinfection of HSV, usually HSV-1, in individuals with atopic dermatitis. Reactivation of HSV is more common than primary infection. Patients with atopic dermatitis are more susceptible to skin infections due to impaired skin barrier function and immune dysregulation. Disseminated cutaneous HSV infection can also occur in individuals with other forms of dermatitis, known as Kaposi varicelliform eruption (KVE)

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Dengue is a prevalent arthropod-borne viral disease in tropical and subtropical areas of the globe. Dengue clinical manifestations include asymptomatic infections; undifferentiated fever; dengue fever, which is characterized by fever, headache, retro orbital pain, myalgia, and arthralgia; and a severe form of the disease denominated dengue hemorrhagic fever/dengue shock syndrome, characterized by hemoconcentration, thrombocytopenia, and bleeding tendency. However, atypical manifestations, such as liver, central nervous system, and cardiac involvement, have been increasingly reported called expanded dengue syndrome. The renal complications of dengue virus infection cover a wide spectrum of manifestations from acute kidney injury to glomerular injury with nephritic/nephrotic syndrome. Majority of cases remain symptom free and show full recovery. We report a 55 years old lady with atypical and rare presentation of dengue disease marked by rapidly progressive glomerulonephritis. Condition improved after initial 5 days pulse methylprednisolone followed by oral prednisolone therapy and mycophenolate mofetil. The main mechanism of dengue glomerulonephritis is still unknown though both direct viral infection and immune mediated damage have been suggested to be the cause. To avoid otherwise preventable morbidity and mortality, physicians should have a high index of suspicion for renal complications in patients with dengue illness and should manage this accordingly

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Objective: This study was conducted to investigate the effects of gabapentin enacarbil (GEn) on sleep EEG, heart rate (HR), blood presssure, anterior tibialis EMG activity (PLMs power) and subjective complaints in subjects with moderate to severe RLS and disturbed sleep. Methods: This was a single site, single-blind, placebo run-in, fixed dose single group polysomnography (PSG) study. Eligible subjects (age 24-66 years) were treated with placebo for one week and GEn (600 mg/day) for 4 weeks. Two in-laboratory PSGs were collected for adaptation and baseline at the end of the placebo run-in period and for re-adaptation and efficacy assessment at the end of the 4-week treatment period. The primary endpoint was the difference in PSG derived cortical arousal intensity (arousal scale, 0-9) associated with PLMs between 4 weeks of treatment with GEn and placebo. Secondary endpoints included changes in HR responses (ΔHR), nocturnal systolic blood pressure (SBP) changes (>10 mmHg) secondary to PLMs and PLMs power. Other PSG and subjective measures were assessed. Results: Of 20 subjects enrolled, 18 completed the study. Subjects treated with GEn did not show significant improvements in cortical arousal intensity and ΔHR. However, subjects showed reduced PLMs power (p= 0.013) and associated reductions in nocturnal SBP per hour of sleep (p= 0.041) GEn showed significant improvement in other PSG parameters and subjective endpoints. Conclusion: The data suggests that GEn reduces the frequency and power of PLMs and the corresponding SBP changes in subjects with RLS. Despite reducing the total number of PLM associated arousals and nocturnal HR, the study did not demonstrate consistent effects of GEn on cortical arousal intensity and corresponding HR changes associated with PLMs. Clinical Trial Registration: ClinicalTrials.gov identifier: NCT02424695

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We report 2 cases of severe injuries in patients with sleep disorders. The first patient sustained multiple orthopedic traumas as sequelae of REM sleep behavior disorders (RBD). The second patient sustained a severe TBI as a result of restless legs syndrome (RLS). To our knowledge, there are only 2 reported cases of severe orthopedic traumas (cervical spine fractures) as a result of RBD and no reported cases of severe TBI from RLS.

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The case was a 7-year-old girl who had complained of bilateral blurry vision for 1 week. Five weeks earlier, she suffered from a flu-like episode with fever, sore throat, and skin rash, and received an irregular dose of oral amoxicillin for 4 days after a diagnosis of scarlet fever. Our clinical examination revealed bilateral panuveitis with frosted-branch angiitis.

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Inflammation has been involved in the pathogenesis of both metabolic syndrome (MS) and atrial fibrillation (AF). The magnitude of elevations in plasma C-reactive protein (CRP) a marker of inflammation is probably related to atrial structural remodeling and impaired atrial function. In patient with MS, limited data exist regarding impact of plasma levels of inflammatory markers, such as C-reactive protein on the: type of AF and atrial structural and functional remodeling.

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Lyme neuroborreliosis (LNB) is a rare infectious disorder of the nervous system caused by Borrelia burgdorferi spirochetes. Different neurological conditions were reported in the disease.

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Patients with human immunodeficiency virus (HIV), mainly those who live under poor sanitary and socioeconomic conditions, are often diagnosed with Gastrointestinal (GI) tract diseases. The lowest CD4+ T-cell counts are not found in the plasma, but in the GI tract, the biggest HIV source, thus allowing opportunistic infections. Therefore, the aim of the present study was to identify the epidemiological factors of GI infections and the prevalent pathogens in HIV patients from Porto Velho City, Rondônia State.

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The heel fat pad cushioning is the result of its structure, shape, thickness. Its morphological modifications due to changes in the amount or distribution of the loads normally sustained by the foot can be disturbed and can result in heel pain. The heel fat pad was found to have a crest on its anterior dorsal surface, flanges on both sides and posteriorly, and a thick portion that reached and covered the posterior surface of the calcaneus and the Achilles tendon insertion. Its anterior internal portion is thinner, and a lump of fat is consistently present in this region [1].

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Intramucosal lipomas are rare colonic polyps that pose diagnostic challenges, but they are important as potential clues to serious medical conditions. One third of intramucosal lipomas are reported to arise in Cowden syndrome, an inherited cancer syndrome.

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