Articles Related to TC

Androgen Insensitivity Syndrome (AIS), also known as testicular feminization, is a rare medical condition that has garnered increased attention in recent years due to evolving research and therapeutic approaches [1,2], as well as the psychological repercussions it has on patients and the risk of being associated not only with sex cord–stromal tumors but also with rare mesenchymal tumors [3]. AIS results from anomalies in the X chromosome and leads individuals with an XY genotype to exhibit various degrees of female physical traits or complete feminine characteristics

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Substance use is a major health concern in developing countries with associated significant burden and challenges with management. In the management of substance use disorders, significant emphasis is place on motivational interviewing which has been found effective and contributes to well being and positive outcome of care. Therefore how long it takes to make a decision about change and sustain such is very critical in the management of drug use.

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Malnutrition is a major challenge in caring for critically ill children. Therefore we aimed to assess the nutritional status in critically ill pediatrics. Methods: This is a prospective observational study carried out on180 children admitted into Pediatric Intensive Care Unit (PICU) of Menoufia University Hospital. Clinical examination performed including anthropometric measurement, screening for malnutrition risk using Pediatric Yorkhill Malnutrition Score (PYMS) and determination of disease severity by Pediatric Risk of Mortality score (PRISM)

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Shin Onodera, Motomi Ishibe (2023) Outcomes Following Debridement, Antibiotics, and Implant Retention with the Exchange of Modular Components in Hip Periprosthetic Joint Infections. J Orthop Physiother 6(1): 101

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Candida albicans is an opportunistic agent that can produce systemic infections in immunosuppressed patients. By varying its cell wall antigens this fungus can evade the immunological response by varying its cell wall antigens. On the other hand, Larrea divaricata Cav. (Jarilla) is a widely spread plant in America and it is used in folk medicine to treat several pathologies. It has been shown that antibodies against Jarilla proteins of crude extract (JPCE) cross-react with proteins of other microorganisms such as Gram-negative bacteria.

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The primary donor sites for collecting bone in the oral cavity to replace missing ridges are the mandibular symphysis or ramus. Although successful, these bone transplants can nevertheless raise a number of issues, including donor site morbidity, nerve paresthesia, the devitalization of native teeth, and postoperative sequelae . Allogeneic block grafts were developed to address these concerns and a lack of autogenous intraoral bone available for grafting

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Large numbers of nations are associated with utilization of anti-toxins regardless of remedy (OTC medications). This DDD/ ATC value contributes to improved antibiotic use quality. The principal objective is to direct improvement of sane medication use of strategies and to give a standard technique for information for future evaluation.

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The transdermal drug delivery system is technique that provides drug through the intact skin. Skin penetration enhancement techniques have been developed to increase the bioavailability of drug substance. These review describes various transdermal patches available in market, types of patches, basic components, polymer used in formulation. The novel drug delivery method do well and complete with those already on the market the main problem that requires consideration include device design and safety, efficacy, ease of handling and economical. Transdermal drug delivery system represent the most attractive method among these because of its low rejection rate, magnificent, ease of administration and better convenience and compliance with patient. This review article provide an overview of transdermal drug delivery system contains various innovative dosage forms. In comparison transdermal patch are effective due to its easy to apply and non-invasive.

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In doped calcium fluoride transparent conducting powder were prepared by solid-state reaction method. Structural properties of the samples were investigated as a function of various In-doping levels (x=0.00-0.01-0.02-0.03). The results of x-ray diffraction have shown that the samples are polycrystalline structure in cubic phase and show presence (111), (220), (311), (400) planes in pure CaF2 sample and the preferred orientation is (220) for pure CaF2 and we have peaks correspond (101), (112), (200), (202) for In for all samples and the preferred orientation is (112) for In for all samples. The average of crystallite size is within the range [2.976-0.845nm] for all samples. The relative intensities, distance between crystalline planes (d), crystallite size (D) and lattice parameters (a) were determined. Measuring the infrared spectrum of pure Calcium fluoride, it is found that there are six vibratory frequencies, namely: (3444.52 - 1517.59 - 1138.40 - 876.40 - 639.93 - 436.29) cm- 1 and six vibratory frequencies for indium doped calcium fluoride at 3wt%. (3441.94 - 1516.77 - 1138.44 - 876.55 - 642.09 -436.44) cm- 1 The study showed that the absorbance values, the absorption coefficient, the refractive index and the optical length were in the indium doped sample by 3wt% greater than that of the pure Calcium fluoride compound and are respectively: α=14.163 cm-1 n=1.767.

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Background: Manifold emulsions are used to increase the bioavailability of active medicinal ingredients and to provide a longer drug delivery mechanism. Hydrophobic and hydrophilic combinational surfactants are frequently used to stabilize the manifold emulsions.

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During the pandemic of Covid-19, pregnant women experience all concerns of pregnancy, physical and mental changes, Covid-19 and its complications, and medical warnings that pregnant women are at high risk. Using an extensive search, all databases including Medline, Web of Science, and Scopus, database were searched. We used of keywords COVID-19, neonatal mortality, neonatal morbidity, pregnancy outcome, or combining these words.

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The European Association of Urology currently recommends partial nephrectomy as the preferred management for localised cT1 renal tumours, irrespective of surgical approach. With the advent of robotic assisted partial nephrectomy, there is growing evidence that warm ischaemia time may be reduced compared to the traditional laparoscopic approach.

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Diabetic macular edema (DME) has become one of the most potential complications that results in loss of vision in patients with diabetic retinopathy. Treatment outcomes that have been predicted directly with advent of machine learning (ML) methods after the initial anti-vascular endothelial growth factor (anti-VEGF) injection, has become extremely vital in the management of DME. Purpose: The aim of this study is to analyze the efficiency of the ML regression models which were developed and validated to predict the possible post-injection central subfield thickness (CST) value and distant vision best corrected visual acuity (DV BCVA) in eyes with DME before the anti-VEGF injection is administered at either treatment initiation or during treatment monitoring. Methods: This retrospective study was conducted in Medical Research Foundation, Chennai, India from January 2010 to December 2020. The model development emphasized on an ensemble ML system consisting of four ML models that were developed and trained independently using the clinical parameters to predict the post injection CST value. The dataset consisting of 906 patients with total of 1874 samples [Optical coherence tomography (OCT) images and clinical parameters] were divided into trained and test set, and the model was validated on test dataset. The predicted CST values was then compared against the respective sample’s post injection actual CST value. The comparative results were measured in terms of Correlation Coefficient and Mean Absolute Relative Error (MARE). Results: On evaluation, we found that Support Vector Regression (SVR) with linear kernel performed best among the other models with four different scenarios in term of both CST and DVBCVA prediction with correlation coefficient of 0.65, 0.73, 0.75, 0.85 and 0.83, 0.87, 0.89 and 0.92 respectively.

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There are several energy drinks available in the market such as Red Bull, Sting, Rebound, Power Up! Triple X Energy Drink, and so on. After the Red Bull drink was introduced in the market in1990s, Energy drinks started to gain popularity and afterwards it became a common name especially among teenagers and young adults [1]. Most energy drinks are caffeinated nonindulgent beverages that are professed to give an additional increase in energy for day-by-day work, increase alertness, and improve athletic performance and mood. There are even certain shreds of evidence present to substantiate these claims, but the effects of these drinks on mental and physical health cannot be neglected. There are reports of adverse events such as insomnia, anxiety, cardiovascular events, seizures, tachycardia, type-2 diabetes, and even death are associated with the consumption of these drinks [2]. This review will focus on energy drinks, their ingredients, health risks associated with these drinks, and will also suggest some recommendations such as changes in marketing, providing education to children regarding adverse effects of these drinks, and further research should be carried out in this domain.

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We investigated a method for preparation of ordered nanopore arrays with the interpore distance of 60 nm by guided self-organization of anodic aluminum oxide with a prepatterned array of pits in the starting Al film.

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