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Articles Related to Toxicology

Impaired Driving Associated with the Synthetic Cannabinoid 5F-ADB

Synthetic marijuana compounds are more potent than ∆9-tetrahydrocannabinol (∆9-THC) and are known to produce a wide variety of clinical symptoms including cardiac toxicity, seizures, and death. Erratic driving by a 45 y/o male was witnessed in the fall of 2017 and roadside evaluation of the driver by the responding law enforcement officer concluded that the driver was intoxicated. Comprehensive analysis of the cigarettes by gas chromatography-mass spectrometry detected the synthetic cannabinoid 5-fluoro-ADB (5F-ADB or 5F-MDMB-PINACA). Validated forensic liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods were used to detect the 5-fluoro ADB metabolite 7 (26.37 ng/mL) in the driver’s blood sample. No other drugs were detected. This case report is one of the first to conclusively show that designer synthetic cannabinoids, commonly referred to as “K2” and “Spice”, can significantly impair driving at relatively low concentrations.
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Fatal road accidents in Spain: psychoactive substances in killed drivers in 2014

Road traffic accidents (RTAs) are often related to impairment by alcohol or drugs. The objectives of this study is to present toxicological data on drivers killed in traffic accidents in Spain in 2014 from a sample of 614 drivers and 240 (out of 614) with positive results for alcohol, illicit drugs and psychoactive medicinal drugs.
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Anti-Inflammatory and Anti-Arthritic Efficacy and Safety of Purified Shilajit in Moderately Arthritic Dogs

The objective of this investigation was to evaluate the efficacy and safety of purified Shilajit in moderately arthritic dogs. Ten client-owned dogs in a randomized double-blinded study received either a placebo or Shilajit (500 mg) twice daily for a period of five months. Dogs were evaluated each month for physical condition (body weight, body temperature, heart rate, and respiration rate) and pain associated with arthritis (overall pain, pain from limb manipulation, and pain after physical exertion).
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Toxicological Screening and Quantitation Using Liquid Chromatography/Time-of-Flight Mass Spectrometry

In recent years, an increasing number of new designer-drugs have increased the demands for general toxicological screening [1]. Limited screening based on immunoassays is commonly used in clinical toxicology, whereas more comprehensive approaches are common in forensic toxicology such as screening based on Gas or Liquid Chromatography (GC or LC) approaches.
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Editorial Board Members Related to Toxicology

Dilek Battal

Associate Professor
Department of Toxicology
Mersin University
Turkey

YUNBO LI

Professor
Department of Pharmacology
Campbell University School of Osteopathic Medicine
United States

Juan Jose Alava

Research Associate
Faculty of Science
The University of British Columbia
Canada

DUARTE NUNO VIEIRA

Professor
Portuguese National Institute of Legal Medicine and Forensic Sciences
University of Coimbra
Portugal

Robert Kinobe

Senior Lecturer
Physiology and Pharmacology
School of Veterinary and Biomedical Sciences
Australia

Esam Z. Dajani

Adjunct Professor of Medicine
Loyola University
USA

D.Sivaraman

Scientist-C
Centre for Laboratory Animal Technology and Research
Sathyabama Institute of Science and Technology, Tamil Nadu
India

BENSON T. AKINGBEMI

Associate Professor
Department of of Anatomy
Auburn University
United States

Sajjad Pourmozaffar

Assistant professor
Iranian Fisheries Science Research Institute
Iran.

Rajendra Singh Chundawat

Associate Professor
Department of Zoology
School of Sciences
Mody University of Science and Technology
India
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