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Articles Related to Toxicology

Copper Oxide Nano-Hydrogel Composite and their Toxicology Studies: A Green Chemistry Approach

The increasing demand for skin care products formulated with metal oxide nanoparticles such as Zinc oxide, Titanium oxide and Copper oxide nanoparticles calls for toxicological safety concerns. Phytochemical assisted synthesis of Copper oxide nanoparticles (CuONPs) has been achieved by a simple, one-pot chemical procedure using polyphenol-rich aqueous extract of Solanum torvum L. as a reducing and capping agent.
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Fatal 2,4-Dinitrophenol (DNP) Ingestion & Use of a Novel Analytical Methodology Testing Post-Mortem Blood Concentrations

2,4-Dinitrophenol (DNP) is readily available online as an unapproved weight loss supplement. Severe systemic toxicity and death have been reported following DNP use.
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The Dose and its Acute Toxicology: A Systematic Review Article in the First Phase of Experimental Pharmacology

Hundreds and thousands of acute toxicity studies are conducted in experimental pharmacology with assumption hypothesis every year. It is usually concluded with inadequately validated data during the period of investigation within 24 hours.
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Impaired Driving Associated with the Synthetic Cannabinoid 5F-ADB

Synthetic marijuana compounds are more potent than ∆9-tetrahydrocannabinol (∆9-THC) and are known to produce a wide variety of clinical symptoms including cardiac toxicity, seizures, and death. Erratic driving by a 45 y/o male was witnessed in the fall of 2017 and roadside evaluation of the driver by the responding law enforcement officer concluded that the driver was intoxicated. Comprehensive analysis of the cigarettes by gas chromatography-mass spectrometry detected the synthetic cannabinoid 5-fluoro-ADB (5F-ADB or 5F-MDMB-PINACA). Validated forensic liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods were used to detect the 5-fluoro ADB metabolite 7 (26.37 ng/mL) in the driver’s blood sample. No other drugs were detected. This case report is one of the first to conclusively show that designer synthetic cannabinoids, commonly referred to as “K2” and “Spice”, can significantly impair driving at relatively low concentrations.
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Fatal road accidents in Spain: psychoactive substances in killed drivers in 2014

Road traffic accidents (RTAs) are often related to impairment by alcohol or drugs. The objectives of this study is to present toxicological data on drivers killed in traffic accidents in Spain in 2014 from a sample of 614 drivers and 240 (out of 614) with positive results for alcohol, illicit drugs and psychoactive medicinal drugs.
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Anti-Inflammatory and Anti-Arthritic Efficacy and Safety of Purified Shilajit in Moderately Arthritic Dogs

The objective of this investigation was to evaluate the efficacy and safety of purified Shilajit in moderately arthritic dogs. Ten client-owned dogs in a randomized double-blinded study received either a placebo or Shilajit (500 mg) twice daily for a period of five months. Dogs were evaluated each month for physical condition (body weight, body temperature, heart rate, and respiration rate) and pain associated with arthritis (overall pain, pain from limb manipulation, and pain after physical exertion).
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Toxicological Screening and Quantitation Using Liquid Chromatography/Time-of-Flight Mass Spectrometry

In recent years, an increasing number of new designer-drugs have increased the demands for general toxicological screening [1]. Limited screening based on immunoassays is commonly used in clinical toxicology, whereas more comprehensive approaches are common in forensic toxicology such as screening based on Gas or Liquid Chromatography (GC or LC) approaches.
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Editorial Board Members Related to Toxicology

Robert Kinobe

Senior Lecturer
Physiology and Pharmacology
School of Veterinary and Biomedical Sciences
Australia

MASAYOSHI YAMAGUCHI

Professor
Department of Hematology and Medical Oncology
Emory School of Medicine
Emory University
United States

Richard Simman

Clinical Associate Professor
Department of Surgery
Wright State University Boonshoft School
United States

Ashraf Naeem

Associate professor
Department of Anatomy & Embryology
Zagazig University
Egypt

NIKOLAS P. LEMOS

Professor
Pathology & Laboratory Medicine
University of California
United States

YUNBO LI

Professor
Department of Pharmacology
Campbell University School of Osteopathic Medicine
United States

Hong Zhu

Associate Professor
Campbell University School of Osteopathic Medicine
United States

Zhuoxiao Cao

Scientist
Cell biology department
Novo Nordisk China R&D
China

Dr. Amarnath Mishra

Assistant Professor
Amity Institute of Forensic Sciences
Amity University
India

Aly Soliman Hamed Derbalah

Professor
Pesticides Chemistry and Toxicology Department
Faculty of Agriculture
Kafr-El-Shiekh University
Egypt
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