Articles Related to Treatment
The Development of a Classification System for the Treatment of Scoliosis by the Side Shift Approach
The Side Shift approach to correction of scoliosis curves has been used by therapist at the Royal National Orthopaedic Hospital (RNOHT) for over 30 years. The Side Shift approach was developed by Mrs Min Mehta, and has been
Modified using consensus based evidence of SOSORT. Clinical observations had indicated that not all patients could actively (Auto) correct to beyond the trunk midline, a key principle of Side Shift. At the RNOHT a classification system based upon the ability of an individual to auto-correct the spine during a Side Shift movement has been developed to aid the appropriate application of the shift exercises and allow future comparative analysi
Diagnosis and Treatment of Atypical Thoracic Outlet Syndrome*
With the progress of society, the development of science and technology, and the popularization of digitalization, the number of patients seeking treatment for "hand numbness" in the outpatient department of rehabilitation medicine is increasing
day by day, and it shows a younger age, even some teenagers; Most of them are diagnosed as cervical spondylosis, but according to the treatment of cervical spondylosis, the effect is not good, sometimes prolonged and not cured, which has different degrees of impact on the work and life of patients, and even affects the physical and mental health of patient
Outcomes Following Debridement, Antibiotics, and Implant Retention with the Exchange of Modular Components in Hip Periprosthetic Joint Infections
Shin Onodera, Motomi Ishibe (2023) Outcomes Following Debridement, Antibiotics, and Implant Retention with the
Exchange of Modular Components in Hip Periprosthetic Joint Infections. J Orthop Physiother 6(1): 101
Recurrent Ophthalmic Eczema Herpeticum with Hyper Immunoglobulin E Syndrome in A 4 Years-Old Boy
Eczema herpeticum (EH) is a skin infection caused by the herpes simplex virus (HSV) that occurs in individuals with atopic
dermatitis. It is characterized by the sudden appearance of vesicles and erosions with crusts over areas affected by eczema.
EH can range from mild and self-limiting in healthy adults to life-threatening in children, infants, and immunocompromised patients. Early treatment with antiviral therapy is crucial in preventing complications and mortality. EH is primarily
caused by a superinfection of HSV, usually HSV-1, in individuals with atopic dermatitis. Reactivation of HSV is more common than primary infection. Patients with atopic dermatitis are more susceptible to skin infections due to impaired skin barrier function and immune dysregulation. Disseminated cutaneous HSV infection can also occur in individuals with other
forms of dermatitis, known as Kaposi varicelliform eruption (KVE)
Case Report: Pyoderma Gangrenosum in IBD Treated with Tofacitinib
Pyoderma gangrenosum is a rare ulcerating skin disease often presenting as an extra intestinal manifestation of IBD and is
difficult to manage. Treatment options for pyoderma gangrenosum include steroids, calcineurin inhibitors and anti TNF
agents. Here in, we report a case of recurrent Pyoderma gangrenosum with Ulcerative Colitis that was successfully managed
with Tofacintib, a JAK inhibitor
Dosimetric Comparison between Intensity Modulated Radiotherapy versus Volumetric Modulated Arc Therapy Treatment Plans for Breast Cancer
This study compared the dosimetric characteristics of Intensity-modulated radiotherapy (IMRT) and volumetric
modulated arc therapy (VMAT) techniques regarding target volume coverage and dose to heart, spinal cord, and lung for
patients with breast cancer. We analyzed the dosimetric differences of plans in the treatment planning system (TPS) between IMRT and VMAT in treating breast cancer. The aim of this study is to compare the dosimetric aspects of IMRT plans
with VMAT according to EMAMI, QUANTEC, and RTOG protocols
Awareness towards Dental and Oral Health among Parents of Children Undergoing Anti-Cancer Treatment
The study aimed to assess the attitudes toward dental and oral health of parents of children receiving anti-cancer
treatment. Methods: This cross-sectional descriptive study was based on a convenience sample of parents of 50 pediatric patients who
were receiving anti-cancer treatment (study group) and 62 parents of healthy children (control group). Questionnaires were
distributed to assess awareness towards oral and dental care.
Study to Find Clinical Characteristics of ABPA in Patients of Severe Bronchial Asthma and Its Relation with Serum Ige Level at Teriary Care Center North India
Allergic bronchopulmonary aspergillosis (ABPA) is an idiopathic inflammatory disease of the lung, characterized by an allergic inflammatory response to colonization of the airways by Aspergillus fumigatus or other fungi. Untreated
or inadequatetreatment may lead to poor outcome in patients. Raised level of serum IgE of more than 1000 IU/ML have
been considered as one if theimportant diagnostic criteria for ABPA, however relation of serum IgE withs severity ofdiseases is lacking. This study was conducted to find out level of serum IgE in patients ofABPA and to find out corelation of
Serum IgE with duration of symptoms and diseasesseverity.
Successfully Treatment of Dental Fluorosis using the Simple Technique of Enamel Microabrasion
Dental dyschromias have several origins among them we cite fluorosis. Dental fluorosis is defined as a qualitative anomaly of the enamel, resulting histologically in hypomineralisation due to excessive ingestion of fluorides during amelogenesis. Clinically, it takes the form of opacities in the enamel. These opacities may affect homologous teeth symmetrically, and generally affect several groups of teeth. Topographically, isolated or confluent white lines or discrete white patches are observed. Interpretismatic spaces are wider, resulting in porous and permeable enamel. On the one hand, this explains the post-eruptive dyschromias, where exogenous pigments penetrate the pores and transform the white opacities into brown. It is classified into 3 categories: mild, moderate and severe. So that this case was moderate fluorosis and appropriated for the treatment with enamel microabrasion. Differential diagnosis for this condition includes: enamel hypoplasia, amoelogenesis imperfecta, and dental caries.
Increasing CD8+ T Cells and Pro-Inflammatory Cytokines is associated with Hypersensitivity Reactions in People Living with HIV-1 under Antiretroviral Treatment
Background: Despite their good efficacy, antiretroviral drugs often induce adverse effects, in particular hypersensitivity reactions (HSR) which cause significant discomfort leading to the abandonment of treatment and then to therapeutic failure in some HIV-positive patients. Therefore, in this study, we aimed to assess the association between immune responses and
hypersensitivity reactions (HSR) induced by antiretroviral treatment in people who living with HIV-1 (PLHIV-1), through the distribution of immune cells and cytokine profiles.
Evaluation of a Theory-Based Behavior Change Intervention to Increase HIV Self-Testing Uptake and Linkage to HIV Prevention, Care, and Treatment Among Hard-to-Reach Populations in Northern Tanzania
Introduction: Tanzania aims for 95% of persons living with HIV (PLHIV) to know their serostatus by 2023.
Methods: An uncontrolled before-after study design was conducted between March 2018 (pre-intervention phase) and July 2018 (post-intervention phase). A total of 183 participants (males=89; females=94) were recruited for this study. Data were collected at baseline and at the one-month and three-month follow-ups using a pre-and post-test semi-structured questionnaire. Descriptive data are presented using measures of central tendency and their respective measures of dispersion. No comparative statistical analysis was performed.
Treatment of pulp and paper mill effluent by the coagulation-flocculation process
Tunisian mill wastewater analyzed for the first time prove high Chemical Oxygen Demand (COD) and high Turbidity values and deserve treatment. The biodegradability index determined by the biochemical oxygen demand (BOD)/chemical oxygen demand (COD) ratio was only 0.072, suggesting its limited biodegradability. Primarily, settling tank showed a positive effect in COD values reduced from 2490 to 448.2 mg/L. In addition, turbidity was reduced from 140 to 65.8 NTU. The coagulation-flocculation process using chemical coagulants-flocculants prior treatment equilibrate this ratio in range 1-2 promises a feasible biological treatment
The Role of Complementary and Alternative Medicine in the Treatment of Insomnia
Insomnia is a frequent condition that can be acute, intermittent, or chronic. It is an unpleasant feeling that makes it difficult to fall asleep. The main aim of the review is to determine the adverse effects of Insomnia drugs and the need to opt for Complementary and alternative medicine (CAM) approach as an adjuvant in treating Insomnia condition with lesser- known side effects. The Methodology involved a detailed literature survey which was performed through an online database, such as Science Direct, Google Scholar, Scopus, Cochrane, and PubMed. The study included original research and book chapters conducted on relation with Insomnia in particular with various therapies used currently and aimed to find possible alternative source which will be effective in treatment as well as with less burden of side effects
Anti-Infectives do not Impact Treatment Response to Immune Checkpoint Inhibitors: a Single Center Retrospective Analysis
Immune-checkpoint inhibitors (ICI) have provided groundbreaking advancements for a
variety of malignancies. It has been of recent interest to identify predictive indicators of response to improve cancer
management using immunotherapy. The intestinal microbiome has been recognized as a potential predictor of ICI anti-
tumor activity. Antibiotics reduce diversity the overall composition of the gut microbiota, with effects seen as quickly as in
a single day. Post-antibiotic dysbiosis recovery varies depending on type and duration of exposure. Preclinical studies in
mice with advanced cancer treated with broad spectrum antibiotics have been associated with resistance to ICI treatment.
Machine Learning Prediction of Response towards Anti-VEGF Injections in Patients with DME: Prediction of Post-Injection CST
Diabetic macular edema (DME) has become one of the most potential complications that results in loss of vision in patients with
diabetic retinopathy. Treatment outcomes that have been predicted directly with advent of machine learning (ML) methods after
the initial anti-vascular endothelial growth factor (anti-VEGF) injection, has become extremely vital in the management of DME.
Purpose: The aim of this study is to analyze the efficiency of the ML regression models which were developed and validated to predict the possible post-injection central subfield thickness (CST) value and distant vision best corrected visual acuity (DV BCVA)
in eyes with DME before the anti-VEGF injection is administered at either treatment initiation or during treatment monitoring.
Methods: This retrospective study was conducted in Medical Research Foundation, Chennai, India from January 2010 to
December 2020. The model development emphasized on an ensemble ML system consisting of four ML models that were
developed and trained independently using the clinical parameters to predict the post injection CST value. The dataset
consisting of 906 patients with total of 1874 samples [Optical coherence tomography (OCT) images and clinical parameters] were divided into trained and test set, and the model was validated on test dataset. The predicted CST values was then
compared against the respective sample’s post injection actual CST value. The comparative results were measured in terms
of Correlation Coefficient and Mean Absolute Relative Error (MARE).
Results: On evaluation, we found that Support Vector Regression (SVR) with linear kernel performed best among the
other models with four different scenarios in term of both CST and DVBCVA prediction with correlation coefficient of
0.65, 0.73, 0.75, 0.85 and 0.83, 0.87, 0.89 and 0.92 respectively.
Editorial Board Members Related to Treatment
IOANNIS D. BASSUKAS
Professor
Dermatology
School of Medicine
University of Ioannina
Greece
Dermatology
School of Medicine
University of Ioannina
Greece
Marco Berlucchi
Department of Pediatric Otorhinolaryngology
Spedali Civili
Italy
Spedali Civili
Italy
ABD EL-FATAH ABOMOHRA
School of Energy and Power Engineering
Jiangsu University
China
Jiangsu University
China
Lin Feng
Associate Professor
Bioinformatics Research Centre
Nanyang Technological University
Singapore
Bioinformatics Research Centre
Nanyang Technological University
Singapore
Mojahid-ul-Islam
Professor
Department of Pharmaceutical Chemistry
Lloyd Institue of management and Tech
India
Department of Pharmaceutical Chemistry
Lloyd Institue of management and Tech
India
MICHAEL VAN DOREN JOHNSTON
Professor
Department of Neurology and Pediatrics
Johns Hopkins University School of Medicine
United States
Department of Neurology and Pediatrics
Johns Hopkins University School of Medicine
United States
Ronald E.P. Frenkel
Voluntary Professor of Ophthalmology
Bascom Palmer Eye Institute
University of Miami School of Medicine
United States
Bascom Palmer Eye Institute
University of Miami School of Medicine
United States
Fuu –Jen Tsai
Professor
Department of Medical Genetics
School of Chinese Medicine
China
Department of Medical Genetics
School of Chinese Medicine
China
Hong Zhu
Associate Professor
Campbell University School of Osteopathic Medicine
United States
Campbell University School of Osteopathic Medicine
United States
S. Vasudevan
Principal Scientist & Professor
Electroinorganic Chemicals Division
Central Electrochemical Research Institute
India
Electroinorganic Chemicals Division
Central Electrochemical Research Institute
India