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Articles Related to Treatment

Cognitive-Behavioral Psychotherapy, a Group Psycho-Educational Workshop and a Workshop for Caregivers of Sexually-Abused Children: a Case Study of Two Mexican Male Children

It has been reported that a large percentage of men and women had experiences of sexual abuse during childhood the effects of which are determined by factors such as age, gender, characteristics of the experience, and cultural aspects, among others. In Mexico, only a limited number of sexual abuse cases are reported to the relevant authorities and even fewer receive adequate care and treatment. This article presents an evaluation of the effectiveness of an individualized cognitive-behavioral treatment involving a group psychoeducational workshop and a workshop for caregivers of two Mexican male children who had experienced sexual abuse. Clinical and cognitive evaluations, pre- and post-test treatment, and follow-up one-and-a-half years later were made. Differences between the two participants were found in all three evaluation periods. Various factors associated with these results are discussed.
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Subacute Facial Nerve Paralysis Following Cyberknife Treatment for Vestibular Schwannoma

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Leriche Syndrome: Percutaneous Treatment with Mechanical Thrombectomy: A Case Report

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The Effect of Different Surface Treatments and Cement Materials on the Bonding between Dentine and Restorative Materials

The aim of this study was to evaluate the effect of different surface treatments and cement materials on the bonding between dentine and restorative materials. In this study, 135 extracted third human molars, three different restorative materials (Cr-Co alloys, composite and zirconia) were used. Acid etching and sandblasting were used the surface of materials and one group was identified to control group. After the surface treatments, restorative materials were bonded to dentine with three cement materials (self-adhesive resin cement, conventional resin cement and glass ionomer cement). The shear bond strength (SBS) test was applied by using a universal testing machine. The statistically analysis of obtained data were performed with use n-way analysis of variance test.The result of n-way analysis of variance test showed that there were statically significant differences either surface treatments or luting cements on the bonding dentine to restorative materials (p=0.001). The results showed that the lowest shear bond value (3.24±3.62 N) was identified in control group of zirconia materials bonded to dentine with glass ionomer cement. The highest shear bond value (94.66±68.36 N) was identified in acid etched composite materials bonded to dentine with conventional resin cement.
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Former Effective Immunotherapy without Adverse Events of Inoperable Epithelial Ovarian Cancers and a Prospect for the Immune Prophylaxis

Current cancer treatments by immune checkpoint blockades are limited due to severe adverse events caused by alteration of the immune system required for homeostasis of normal tissues. Common cancer chemotherapy alters the quality of patients’ lives. Platinum-based treatment can lead to severe neurotoxicity with chronic debilitation. Additionally, survival of patients with epithelial ovarian cancers (EOCs) has remained poor despite extensive cytoreductive surgery, high dose chemotherapy, checkpoint blockades and immunotherapies effective in some other types of cancer. The pathobiology of EOC cancer stem cells (CSCs) is not well understood. Observations demonstrate that EOCs exhibit in vivo two distinct CSC types - perivascular diploid CSCs dividing asymmetrically with the help of the host suicidal CD8+ T cells, and haploid CSCs at the cancer abdominal surface originating from meiosis I cytokinesis of bulk surface cancer cells. The perivascular CSCs contribute to the cancer cell bulk and, via left ovary venous blood, can cause EOC liver metastases. Haploid CSCs released from the bulk cancer surface cause the common pelvic and abdominal EOC spread. Former elimination of the host antibodies blocking T cell effectors by intermittent doses of cyclophosphamide exhibiting significant immunomodulatory anticancer effects, facilitation of the immune system reactivity against alloantigens of cancer cells by blood transfusions, and augmentation of anticancer immunity by bacterial toxins, resulted during the subsequent treatment-free period into rejection of inoperable EOCs without any adverse events during the treatnment. To help prevent cancer relapses, patients treated for advanced primary epithelial cancers should be considered as candidates for continuously stimulating immune anticancer activity by treatments such as daily metformin and weekly lentinan consumptions.
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Assessment of the Efficacy, Safety and Cost-Effectiveness of Micafungin Compared to Caspofungin and Low Dose Liposomal Amphotericin B for the Treatment of Candidaemia and Clinically Diagnosed Invasive Candidiasis: A Retrospective Audit

Despite several studies having highlighted that candidaemia and invasive fungal disease (IFD) are associated with high mortality and increased costs, there are currently few published studies which provide an insight into real-life practice of invasive candidal diseases. In a medium-sized district general hospital in the UK we sought to compare the efficacy, safety and treatment cost of micafungin versus caspofungin and low dose of liposomal amphotericin B (L-AmB) 1mg/kg/day for the treatment of confirmed candidaemia or clinically diagnosed invasive fungal disease (CDIFD). In the present retrospective audit, a total of 126 patients with candidaemia or CDIFD were reviewed from hospital records and 94 were included in our audit.
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Sustaining HIV Prevention, Care and Treatment Programmes for the Youths in Chipata Districts through Youth Leadership

Comprehensive HIV prevention information, access and utilization of Sexual and Reproductive Health(SRH) services, is low among the migrants mobile and displaced populations of our catchment area namely Katete, Chadiza and Chipata in district in the eastern province of Zambia. This is one of the provinces with a highest number of, migrants; sex workers truck drivers and cross border traders due to the economical Nacala corridors that bring the three countries namely Zambia, Malawi and Mozambique, also the traditional ceremonies that bring the three countries together each year has seen high numbers of people migrate between the three countries this has led to high numbers of STIs, HIV and unsafe abortions. Alcohol and substance abuse, peer pressure among this population.
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Labetalol in Comparison to Methyl Dopa in Treatment of Gestational Hypertension, A Randomized Trial

To evaluate the value and safety of labetalol in comparison to Alfa methyldopa in treatment of pregnant women with pregnancy-induced hypertension (PIH). 264 patients with PIH were randomly distributed to take either methyldopa (group 1) labetalol (group 2). or Intake of medications with respect to Age, gravidity, Blood Pressure measurement, albumin in urine measurement Levels, Side Effects, dose of the drug, increasing duration of pregnancy, mode of delivery, Perinatal safety and APGAR scores were studied. The statistical level of significance was taken at P<0.05.
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Neuropsycological Function, Insight, and Treatment Adherence among Patients with Schizophrenia

Research has suggested that poor insight in patients with schizophrenia is associated with poorer treatment compliance. One factor ontributing to poor insight may be neurocognitive deficits. The aim of the current study is to explore the relationship between cognitive insight, clinical insight, treatment adherence, executive functions and sustained attention within patients with schizophrenia. The study was conducted on 41 patients with schizophrenia using the Beck cognitive insight scale, the schedule for assessment of insight, the drug attitude inventory and two neuropsychological tests.
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Infantile Acute Generalized Pustular Psoriasis: A Case Report

Generalized pustular psoriasis (GPP) is an acute and uncommon form of psoriasis, representing about 3% of all psoriasis cases. Triggers may include streptococcical infections, emotional stress, vaccinations and exposure to medications such as penicillin. Systemic therapy is often necessary for GPP, since it may rapidly evolve, leading to significant and potentially fatal complications. Here, we describe the case of a 5-year-old male presenting with diffuse erythema, confluent scaly plaques and painful pustules localized on the trunk and limbs. Systemic manifestations such as fever, general lymphadenopathy and arthritis were also observed. To date, no standardized treatment guideline exists for infantile acute generalized pustular psoriasis. Our patient responded successfully to cyclosporine treatment within 4 weeks without any side effects. Thus, cyclosporine could be considered a useful agent in cases of pediatric GPP, keeping in mind its side effect profile in child population.
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Three Stages of Evolution in the Treatment of Acute Ischemic Stroke: Stroke Unit Care, Intravenous Thrombolysis and Endovascular Therapy

Ischemic stroke is the most frequent cause of disability in adults in the world and its treatment remains a challenge. The care management of stroke patients in organized stroke units has improved and various revascularization approaches have emerged during the past decades. Stroke patients cared in organized stroke units are more likely to survive, to return home and to be functional independency. It is recommended that all patients with stroke, regardless of age, should be cared in a stroke unit. Intravenous thrombolysis with recombinant tissue plasminogen activator delivered within 4.5 hours after symptom onset is the only approved and effective medical therapy in patients with acute ischemic stroke.
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Prevention and Treatment of Esophageal Cancer in China: Achievements and Challenges-Prevention is the Key

Background: The study investigated esophageal cancer etiology and pathology, along with problems associated with surgical treatments. Keywords: Esophageal cancer; Mortality; Etiology; Pathology; Treatment; 5-year survivalIntroduction Methods: Data from the National Cancer Prevention and Control Office and the National Cancer Registry Center (2012) were assessed for information regarding malignant tumor incidence. These data were also used to conduct a mortality analysis and investigate death records pertaining to esophageal cancer patients. We extracted crude and age-specific mortality data and proportional mortality ratios as well as standard mortality data for Chinese and world populations. Esophageal cancer mortality was compared with death statistical data and literature related to esophageal cancer was collected from the Chinese Biomedical Literature Database and the Chinese Journal Network.
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Treatment of Cerebral Mucormycosis with Prolonged Liposomal Amphotericin B (>1000 days)

Mucormycosis is a rare but invasive and potentially lethal infection caused by ubiquitous fungi of the order Mucorales. The primary mode of infection is inhalation of fungal spores. Rhinocerebral and pulmonary infections are most common, however, other organ systems including the central nervous system can be affected, presumably by occult fungemia. We describe the prolonged treatment course (>1000 days) of a patient with cerebral mucormycosis using liposomal amphotericin B (LAMB). Two different attempts were made to replace LAMB with posaconazole, but each occasion resulted in therapeutic failure. This case represents the longest course of LAMB reported in the literature.
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Dosimetric Evaluation of Total Body Irradiation (TBI) Treatment by Volumetric Modulated Arc Therapy (VMAT) on the Coach

To compare three different types of volumetric modulated arc therapy (VMAT) planning techniques using Elekta Versa HD lineer accelerator to deliver total body irradiation (TBI) treatment on the coach and to evaluate the feasibility of VMAT planning technique for TBI treatment.
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HIV-1 Molecular Characterization and Transmitted Drug Resistance Prevalence among Treatment-Naïve Individuals

The distribution of different human immunodeficiency virus type 1 (HIV-1) genotypes and the prevalence of transmitted drug resistance (TDR) mutations vary greatly across different Brazilian regions. This study aimed to describe the HIV-1 molecular diversity and TDR prevalence among treatment-naïve HIV-1 infected individuals in an urban area of Northeastern Brazil. DNA samples from 97 infected individuals were obtained and pol sequences were generated by Polimerase Chain Reaction (PCR) and direct sequencing. Bioinformatics tools were used to identify the presence of associated mutations with drug resistance, to reconstruct the phylogeny and to detect recombination.
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Editorial Board Members Related to Treatment

Robert R. Redfield

Department of Immunology and Microbiology
University of Maryland
United States

Guey-Jen Lee-Chen

Department of Life Science
National Taiwan Normal University

Chang Ming Charlie Ma

Department of Radiation Oncology
Fox Chase Cancer Center
United States

Yun Dai

Associate Professor
Department of Medicine
Virginia Commonwealth University
United States

Hong Zhu

Associate Professor
Campbell University School of Osteopathic Medicine
United States

Peter Majewski

School of Engineering
University of South Australia

Miklas Scholz

Water Resources Engineering
Lund University

Qifeng Yang

Department of Breast Surgery
Director, Pathology Tissue Bank
Qilu Hospital, Shandong University

Agnieszka Alicja Karczmarczyk

Assistant professor
Faculty of Civil and Environmental Engineering
Warsaw University of Life Sciences


Department of Neurology and Pediatrics
Johns Hopkins University School of Medicine
United States
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