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Articles Related to Treatment

The Effect of Salbutamol Nebul Treatment on Systolic Pulmonary Artery Pressure in Newly Diagnosed Patients with Chronic Obstructive Pulmoner Disease

The occurrence of pulmonary hypertension [PHT] in patients with chronic obstructive pulmoner disease [COPD] usually indicates progression of the disease and poor prognosis. The aim of this study is to investigate the effect of oxygen and bronchodilator treatment on systolic pulmonary artery pressure induced by exertion test in patients with COPD.
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Treatment of Moderate Fluorosis with Combined Bleaching Protocols

The patient’s concern was the appearance of her maxillary and mandibular teeth, which had a mottled, brown-yellow enamel dysmineralization due to moderate fluorosis. The patient was 45 years old, and lived in Isparta region where drinking water has high concentration of Fluoride ion. Patient was a female doctor and was concerned that the appearance of her teeth would negatively impact interactions with her patients and social life.
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Modified and Combined Lateral and Posterolateral Approach an Alternative Treatment to Tibial Plateau Fractures

The selection of a surgical approach for the treatment of tibia plateau fractures is an important decision. Approximately 7% of all tibia plateau fractures affect the posterolateral corner. Displaced posterolateral tibia plateau fractures require anatomic articular reduction and buttress plate fixation on the posterior aspect. These aims are difficult to reach through a lateral or anterolateral approach. The standard posterolateral approach with fibula osteotomy and release of the posterolateral corner is a traumatic procedure, which includes the risk of fragment denudation. Isolated posterior approaches do not allow sufficient visual control of fracture reduction, especially if the fracture is complex. Therefore, the aim of this case report was to present a surgical approach for posterolateral tibial plateau fractures that both protects the soft tissue and allows for good visual control of fracture reduction. The approach involves a lateral arthrotomy for visualizing the joint surface and a posterolateral approach for the fracture reduction and plate fixation, which are both achieved through one posterolateral skin incision. Using this approach, we achieved reduction of the articular surface and stable fixation in patients at the final follow-up visit. No complications and no loss of reduction were observed. Additionally, the new posterolateral approach permits direct visual exposure and facilitates the application of a buttress plate. This approach does not require fibular osteotomy, and fragments of the posterolateral corner do not have to be detached from the soft tissue network.
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Management Protocol for Patients with Down syndrome associated with Alzheimers disease

Down syndrome is one of the most common chromosomal alterations and due to the incremental in the oval life expectancy and its relationship with Alzheimer disease; the professionals have to be aware of the oral and behavioral characteristics to give patients an excellent treatment.
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Artisanal Cannabis in Young and Adults Patients with Treatment Resistant Epilepsy: Prospective, Observational, Open-Label Study in Argentina

Background: A third of patients with epilepsy have a drug-resistant form. We aimed to observed whether addition of artisanal cannabis to existing anti-epileptic treatment would be safe, and efficacious in young and adults with drug-resistant epilepsy. Methods: Patients (aged 12-51 years) with severe, intractable epilepsy, who were receiving stable doses of antiepileptic drugs before study entry, were enrolled in an expanded-access programme at our epilepsy centre.
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Monotherapy versus Combination Therapy for the Treatment of Pseudomonas Aeruginosa in Cystic Fibrosis Patients

Infection with Pseudomonas aeruginosa in cystic fibrosis (CF) patients is a strong contributor to respiratory failure and associated mortality. Bacteria colonizing a cystic fibrosis lung commonly form biofilms that greatly contribute to increased antibiotic resistance and hypermutability. Antimicrobial treatment in these cases can be either through the use of a single agent (monotherapy) or through a combination of agents (combination therapy).
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Quality of Life after Accidental Major Vascular Injury and Prolonged ICU Stay - A Case Report

Survival or mortality rate is a reasonable choice of an outcome measure for critically ill patients in intensive care unit (ICU). But it is also important to assess the impact of critical illness and peri-operative complications on health status and quality of life (QoL) after hospital discharge. The QLQ-C30 is a 30-item cancer-specific questionnaire that incorporates five functioning scales (physical, role, cognitive, emotional, and social), eight symptoms scales, perceived financial impact of the disease and a global scale [1-5].
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Benign Pulmonary Metastasizing Leiomyoma

Benign metastasizing leiomyoma (BML) is a rare event that occurs in middle aged women with a history of uterine myomas. It is characterized by multiple leiomyomatous lesions in many tissues and organs, especially in the lungs. We report the case of 56 years old woman presenting chronic cough, hemoptysis and having a history of myomectomy for a uterine leiomyoma 6 years ago. Chest CT showed a right pulmonary process. The histological diagnosis was defined by bronchoscopy and biopsies. The surgery was not an option because of the bronchovascular extension of the tumor, so hormonal therapy was administrated to the patient. One year later, Chest CT showed that the tumor doesn’t increase.
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Caenorhabditis elegans (C. elegans) Used as a Whole Model Organism to Identify New Anti-Infectives Therapeutic Agent for MRSA Pathogens - A Review Paper

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the greatest fears with the number of serious infections on human health regarding antibiotic resistance. It causes a wide range of infections and bacteremia, ranging from inconsequential superficial skin infections, wound suppuration, even pneumonia or deep-seated tissue infections, which may lead to sepsis and fatalities.
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Rebleeding In Central Nervous System after Use of Rivaroxaban for Treatment of Deep Venous Thrombosis in a Patient with Cerebral Vasculitis

Introduction: Rivaroxaban is a direct, specific inhibitor of Factor Xa, which targets Factor Xa and Factor Xa free and coagulated in the prothrombinase complex. Objective: To report a case of CNS rebleeding after using Rivaroxaban for treatment of DVT
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Novel Alternative Treatment to Plasmapheresis in Evans Syndrome

Evans syndrome is a rare haematological disease characterised by concurrent occurrence of autoimmune haemolytic anaemia (AIHA) and idiopathic thrombocytopenic purpura. The autoimmune haemolysis can lead to hyperbilirubinaemia, profound anaemia and haemodynamic instability. It can be difficult to treat and when refractory to medical treatment it could necessitate emergency splenectomy. Plasmapheresis is used in refractory haemolytic anaemia to aid removal of disease causing autoimmune complexes whilst immunomodulators act to reduce autoantibody response and effectiveness. However, this is an expensive and resource intensive process that is limited to tertiary referral centres. In this case study we present a successful novel alternative for life threatening AIHA in Evans Syndrome using haemofiltration with on-going fresh frozen plasma transfusion when resources are limited or it is not an accessible method.
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Dawn of the Biofilm Disease: Highlights about Biofilm in Bone and Joint & Prosthetic Joint Infections Pathogenesis, Diagnosis and Treatment

I present some key considerations of the biofilm disease as part of two complex pathologies such as bone and joint infections and prosthetic joint infections, taking into account the bacterial pathogenic factors to understand the particular nature of these infections, and to achieve an accurate diagnosis and management beyond the antimicrobial therapy. I mention some personal experience of many years in the medical microbiology laboratory and next to the patient’s bed.
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Tomotherapy Treatment of Chronic Lymphocytic Leukemia and Ocular Lymphoma

A sixty-five-years-old male patient with history of non-Hodgkin’s lymphoma of the right orbit and a fifty-years-old female patient with chronic lymphocytic leukemia with peripheral lymphocytosis were treated on TomoTherapy. In the first case, a 1 cm beam was used for planning a delivery of 30.6 Gy in 17 fractions with a sequential boost of 9 Gy in 5 fractions. Tumor involvement of the ipsilateral lens and lacrimal gland in the planning target volume necessitated a compromise between preserving patient’s vision and delivery of tumoricidal dose to the target. In the second case, 30 Gy in 20 fractions delivery was planned with a 2.5 cm beam. The tumor extended anteriorly and this technique allowed sparing more orbital tissue and required a high modulation factor.
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Successful Treatment of Acquired Amegakaryocytic Thrombocytopenia (AAT) with Cyclosporine and Eltrombopag: A Case Report

Acquired amegakaryocytic thrombocytopenia is an unusual hematological disorder characterized by severe thrombocytopenia in association with a marked decrease, or the absence, of megakaryocytes in bone marrow. Its pathogenesis is not well understood and its clinical course is variable. Several treatments have been used, producing different responses. We present a case that was successfully treated with a calcineurin inhibitor combined with a thrombopoiesis-stimulating agent.
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Management, Clinical Course and Treatment Outcome of Postpartum Uterine Atony

By reporting a case series from a referral hospital we aimed to determine the treatment options and outcomes of one of the serious complications of the labour uterine atony refractory to the medical treatment. In this study, a total of 58 postpartum uterine atony cases refractory to uterotonic treatment and managed with intrauterine balloon tamponade, B-Lynch suture, internal iliac artery ligation or hysterectomy was a retrospectively analyzed. Initially, thirty two cases managed with intrauterine Bakri balloon tamponade and six B-Lynch compression sutures alone, in eight cases both procedures were done together. Eight cases managed with internal iliac artery ligation and four hysterectomies. Our success rate with intrauterine Bakri balloon tamponade, B-Lynch compression suture and internal iliac artery ligation were 84.4%, 83.3%, 75% respectively in stopping postpartum haemorrhage regarding uterine atony and the most successfull rate was obtained with the Bakri balloon tamponade in the combination with B-Lynch compression suture 87.5%. The median estimated blood loss was 2018ml, intraoperative median hemoglobin was 5.8 mg/dl and the median amount of blood transfused was five units, the median volume infused into balloon was 285ml; balloon was in place for a median duration of 36 hours. In 6 cases Bakri balloon tamponade with or without B-Lynch compression sutures failed to stop haemorrhage and hysterectomy required. In two patients Asherman’s syndrome and infertility, in two patients’ amenore were developed and uterine prolapse was observed in 2 patients, one of which was uterine necrosis. No maternal mortality was observed.
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Editorial Board Members Related to Treatment

Marco Berlucchi

Department of Pediatric Otorhinolaryngology
Spedali Civili
Italy

KEQUAN ZHOU

Associate Professor
Department of Nutrition & Food Science
Wayne State University
United States

CHI-HIN CHO

Professor
School of Biomedical Sciences
The Chinese University of Hong Kong
Hong Kong
China

Luis Ulloa

Associate Professor
Department of Surgery
Rutgers New Jersey Medical School
United States

Antoine Trzcinski

Lecturer in Water and Environmental Engineering
Faculty of Engineering
University of Southern Queensland
Australia

GEORGE E. WOODY

Professor
Department of Psychiatry
University of Pennsylvania and Treatment Research Institute
United States

Avinash Shankar

Chairman
National Institute of Health & Research
Warisaliganj (Nawada), Bihar
India

JOHN EVANS

Professor
Department of Obstetrics and Gynaecology
University of Otago
New Zealand

Jianfei Qi

Assistant Professor
Biochemistry and Molecular Biology
University of Maryland School of Medicine
United States

Chunying Li

Assistant Professor
Department of Biochemistry and Molecular Biology
Wayne State University School of Medicine
United States
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