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Articles Related to Tumor

Buschke-Lowenstein Tumor of the Vulva: A Case Report

Buschke-Lowenstein tumor or giant condyloma acuminata is a rare disorder of the external genitalia, belonging to the group of verrucous carcinomas, and usually affects immunocompromised men. Human Papillomavirus (HPV) 6 and 11 are potentially involved in the pathophysiology. A detailed questioning, a rigorous clinical examination and complementary imaging are important to establish an accurate lesion assessment and an adapted management. Wide surgical excision is the treatment of choice.
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CNS Gliosis not Neoplasia in Kabuki Syndrome: A Case Report of a Brain ‘Tumor

An eight-year-old boy with Kabuki Syndrome (KS) and an enlarging CNS mass is presented. The ‘tumor’ was discovered incidentally during MR imaging for a behavioral disorder and was located within the left globus pallidus. Retrospective review of previous MRIs showed no abnormality in the basal ganglia seven years earlier but a small region (a few pixels) of increased in T2 signal intensity three years earlier.
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Cranial Vault Tumor Revealing Metastatic Thyroid Carcinoma

Distant metastases from follicular thyroid carcinoma are not uncommon, but bone localization in the cranial vault is extremely rare. Although these metastases have a poor prognosis, early diagnosis and appropriate treatment can improve quality of life. We report a case of follicular thyroid carcinoma revealed by a metastasis of the cranial vault initially diagnosed as meningioma.
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Synchronous Contralateral Benign and Malignant Parotid Gland Tumors: Case Report

Multiple primary parotid gland tumors are rare, accounting for 1.7-5% of all parotid neoplasms, and the occurrence of bilateral parotid gland tumors is even lower (1.3-3.5%). These tumors can be synchronous or metachronous and the most common histologic type of bilateral parotid gland tumors is Warthin tumor (79.2-90%). Combined benign and malignant lesions and bilateral neoplasms of different histologic types are even less frequently found.
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After Brain Tumor Surgery: Catheter-Related Bacteremia of Chryseobacterium indologenes Development in Central Nervous System of An Infancy. A Case Report

40-day male infant has admitted to the hospital by family. He has a complaint including lack of suction, vomiting, decreased of movements and continuous sleep about a week of ongoing. Brain computed tomography recognized a mass (with hyperdense hemorrhage) in the posterior fossa and right cerebellar hemisphere.
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Cost-Effectiveness and Budget Impact Analysis of Recombinant Tumor Necrosis Factor-Thymosin Alpha 1 in a Complex Treatment of Metastatic Breast Cancer

Recombinant tumor necrosis factor -thymosin alpha 1 (TNF-T) has been used in Russian oncological practice for a number of years.
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Intracranial Inflammatory Pseudotumor: A Case Report and Review of the Literature

Inflammatory pseudotumors are lesions characterized by inflammatory cell infiltration and fibrosis. Central nervous system (CNS) inflammatory pseudotumors are much rarer, and generally manifest in the sellar and parasellar regions. We report a patient with an inflammatory pseudotumor in the temporal and occipital lobes treated in our department in 2017, and present a literature review. We discuss the etiology, imaging, pathology, and treatment of intracranial inflammatory pseudotumors.
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A Clinical Case Study of Paratesticular Rhabdomyosarcoma of Young Adult

Para-testicular rhabdomyosarcoma (RPT) is a rare tumor of children and adolescents. The diagnosis is made by the anatomopathological study. The treatment must be multimodal and involves surgery, chemotherapy and radiotherapy. We report the case of a 19-year-old adolescent in our department for an embryonic-type para-testicular rhabdomyosarcoma. Our aim is to expose a rare and unknown case that may be life-threatening. We would like to emphasize on the fact that paratesticular rhabdomyosarcoma need to be brought up in front of a tissular process expanding in the scrotum with normal testicules.
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Granular Cell Tumor of the Tongue: 2 Cases Report and Review of the Literature

Granular cell tumor, also known as Abrikossoff tumor, is a rare lesion that arises from the nervous system. Most of these tumors are benign and only 1-2% are malignant. Although they can be found in any part of the human body, 45-65% appears in the head and neck region, mainly in the oral cavity. Here, we report 2 cases of granular cell tumor of the tongue, diagnosed by excisional biopsy. Until the present moment, both patients remain with no recurrence.
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Importance of Complete Clinical History in the Management of Parakeratinized Odontogenic Keratocyst: Case Report

The Odontogenic Keratocyst considered potentially aggressive and of high recurrence located between 30 and 60%, with clinical and radiographic characteristics not clearly defined. It occurs at any stage of life. The 70 to 80% of the cases are located in the jaw, commonly in the area of the lower third molar and mandibular angle from where they progress towards the branch and the body. The lesions are long latent, often asymptomatic and can reach remarkable dimensions without significant deformation of the jaw bones. They are often found during the routine radiographic examination.
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Monoclonal Antibodies for the CIGB-552 Antitumor Synthetic Peptide Quantification

The CIGB-552 peptide is a synthetic peptide that exerts cytotoxic effect on tumor cells. Thus, CIGB-552 peptide quantification in patient samples is crucial for assessing the treatment efficacy. Therefore, this study describes the generation and characterization of monoclonal antibodies (mAb) directed against the CIGB-552 peptide to be used in a quantification assay in further pharmacokinetic studies in humans. In this sense, the CIGB.552-H294 mAb specificity was evidenced only against the CIGB-552 peptide and a metabolite of 17 amino acids resulting from the CIGB-552 peptide degradation detected in mouse sera.
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Profile of Tumor-Associated Cytokines among Breast Cancer Patients: A Preliminary Study

The link between disease and the oral cavity represent clinically important factors that have given rise to the interest in using saliva as a diagnostic fluid for systemic diseases. The objective of this study was to detect and quantify cancer related cytokines in the saliva of women with breast cancer and compare their concentrations to a healthy cohort.
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The Incidence and Durability of Compensatory Hypertrophy in Pediatric Patients with Solitary Kidneys

To evaluate the incidence and durability of compensatory hypertrophy with solitary kidneys in the setting of those with multicystic dysplastic kidney or Wilms tumor status post nephrectomy. We conducted a retrospective cohort study of patients with multicystic dysplastic kidney (MCDK) and Wilms tumor (WT). MCDK patients were verified by sonographic findings prenatally. WT patients entered our study at time of nephrectomy. We compared the natural history of hypertrophy between the two cohorts via renal length measurement. We performed linear regression to predict creatinine clearance from renal length after adjusting for age and cohort status (MCDK v. WT).
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Comparative Study for Efficacy and Safety of Biosimilar Infliximab in Patients with Active Rheumatoid Arthritis on a stable Dose of Methotrexate

The present study evaluated the efficacy and safety of biosimilar infliximab in patients with active rheumatoid arthritis on a stable dose of methotrexate. Subjects were assigned randomly to either study infliximab or reference infliximab product in an approved dose of 3 mg/kg as an intravenous infusion at week 0, followed by similar doses at Weeks 2, 6 and 14. Primary efficacy endpoint was the proportion of subjects achieving ACR20 criteria at week 16 and secondary efficacy assessment included proportion of subjects achieving ACR20, ACR50 and ACR70 at week 16. In the open-label phase, all responders were followed till week 54. The non-responders entered a follow-up phase for immunogenicity and safety for an additional 3 months.
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Osteoid Osteoma of the Ribs - Is Image Intensifier or Bone Scintigraphy a Mandatory Diagnostic Tool - A Case report with Review of Literature

Osteoid osteoma (OO) is a benign bone tumour. In 1935, the jaffe reported it first. The fifty percent of OOs occur in long bones of the lower extremities but it may affect any bone. Only 1 % OOs affects the ribs and surgical excision was reported only in 14 cases in the literature. Complete surgical excision is the standard treatment method for osteoid osteoma is complete surgical excision which is reserved for the patients not responding to conservative treatment. In this report, we present a case of osteoid osteoma of the posterior part of the shaft of the sixth rib affecting a 30-year-old male, who had presented with symptoms of severe pain over the affected area and underwent surgical resection. Excised rib segment showed no osteosclerotic lesion on X-ray so immediately extended resection of the sixth rib was done. Here we have tried to evaluate the importance of the presence of the skeletal scintigraphy or C Arm image intensifier intraoperatively by comparing our experience with the available literature.
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Editorial Board Members Related to Tumor

Nallasivam Palanisamy

Associate Professor
Michigan Center for Translational Pathology
University of Michigan
United States

Yaguang Xi

Assistant Professor
Mitchell Cancer Institute
University of South Alabama
United States

Pankaj Srivastava

VATS Surgeon
Om Surgical Center & Maternity Home
Varanasi
India

Qifeng Yang

Professor
Department of Breast Surgery
Director, Pathology Tissue Bank
Qilu Hospital, Shandong University
China

Marwa Hamdy El-Wakil

Faculty of Pharmacy
Pharmaceutical Chemistry Department
Alexandria University
Egypt

Arif Gulzar

Department of Material Science and Chemical Engineering
Harbin Engineering University
China

Nejat Dalay

Professor
Istanbul University Oncology Institute
Turkey

Ramani Ramchandran

Professor
Department of Pediatrics
Medical College of Wisconsin
United States

SONAL GUPTA

Assistant Professor
Department of Pathology
University of Texas MD Anderson Cancer Center
United States

Huafeng Zhang

Professor
School of Life Science
University of Science & Technology of China
China
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