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Photodegradation, Antibacterial & Antioxidant Assessment of Multifunctional Zinc Oxide Metal Nanoparticles Using Smilax aspera Leaf Extract: An Eco Approach

The endeavor of this research accounts for a superficial green route scheme by using an extract of leaves of Smilax aspera as a stabilizing and capping agent. Zinc Oxide nanoparticles (ZnO-NPs) were examined through UV-visible Spectrophotometer, X-Ray Diffraction (XRD), EDX (Energy Dispersive X-rays spectroscopy), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM). The NPs demonstrates potential photo catalytic activity for the degradation of Methyl Orange (MO) and Methylene Blue (MB) dyes upon exposure to sunlight.
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An Adjuvant Approach to Alleviate Reoccurring or Treatment Resistant Symptoms of IBD in Companion Animals

Inflammatory bowel disease (IBD) is a common yet distressing condition afflicting tissues of the gastrointestinal (GI) tract in companion animals; symptoms include vomiting, diarrhoea, loss of appetite and weight loss. Pathogenesis of IBD may link to both diet and parasitic or bacterial infections of the gut. Although current treatments may provide some relief to the animal, unfortunately recurrent flaring of symptoms is not uncommon. Therapeutic interventions available to the veterinarian include those that focus on treating any underlying infection and or a change in diet, both employed with the aim of reducing inflammation.
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Management of Gluteal Adjuvant Disease by Resection and Rotation of PreExpanded Lumbar Flaps

The adjuvant human disease is defined as any clinical manifestation associated with the parenteral administration of adjuvant substances purposes and that occurs at least 3 months after administration.
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A Bioequivalence Study of Two Formulations of Rosuvastatin

Aim of this study was to compare the bioavailability of two tablet formulations containing Rosuvastatin: Rosuvastatin tablets 40 mg manufactured by MacLeods Pharmaceuticals Ltd. (marketed in Italy with the brand name Exorta®) and CRESTOR® 40 mg tablets marketed by Astra Zeneca.
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First Known Case of Juvenile Gigantomachia in the United Kingdom - A Case Report

Gigantomastia is a rare condition which remains poorly understood. There is no universally accepted definition, however breast weight exceeding 3% of total body weight has been proposed. Juvenile gigantomastia, a subtype, involves sudden onset, excessive growth of breast tissue in relation to puberty and can occur before or after the onset of menstruation. This paper reports on the first known case of juvenile gigantomastia seen in the United Kingdom. A 16-year old female presented with a 12-month history of rapid breast growth. She had no other medical problems and no relevant family history. Examination revealed bilaterally enlarged breasts extending to the level of the anterior superior iliac spine, with enlarged superficial veins, ill-defined areola and areas of skin ulceration. A range of hormone and autoimmune tests were performed with all results found to be normal. After MDT discussion, the treatment of choice was reduction mammoplasty with an inferior pedicle technique and free nipple grafting if necessary. The total volume of tissue removed weighed 10.9 kg; 6.6 kg from the right breast, 4.3 kg from the left breast. Initial post-operative results demonstrate a highly satisfactory reduction with minimal scarring and no further growth of breast tissue. Histology showed a benign pattern secondary to extensive proliferation of glandular and stromal tissue. The tissue tested positive for both oestrogen and progesterone receptors and so the decision was made to treat the patient with tamoxifen until the age of 21 years in order to prevent recurrence. To our knowledge, this is the first reported case of juvenile gigantomastia in the UK.
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Long-Term Outcome of Juvenile Idiopathic Arthritis in Early Adulthood: Clinical Experience from a Saudi Tertiary Hospital

To report the long-term outcome including disease activity, damage and social status, quality of life at the last follow-up visit in a Saudi cohort of adults with juvenile idiopathic arthritis (JIA), and to determine the predictive factors.
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Efficacy of Chitosan as Vaccine Adjuvant Against Paracoccidioidomycosis in Mice

Paracoccidioidomycosis (PCM) is a systemic disease caused by thermo- dimorphic fungi of Paracoccidioides genus that is endemic in several Latin American countries. The treatment for this disease can be performed with different drugs. In general, it is a long duration treatment that aims the control of the clinical manifestations. Even after treatment, the patient usually shows relapse and incapacitating sequelae, such as fibrosis and pulmonary emphysema.
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Sequence Variant in the TRIM39-RPP21 Gene Readthrough is Shared Across a Cohort of Arabian Foals Diagnosed with Juvenile Idiopathic Epilepsy

Juvenile idiopathic epilepsy (JIE) is a self-limiting neurological disorder with a suspected genetic predisposition affecting young Arabian foals of the Egyptian lineage. The condition is characterized by tonic-clonic seizures with intermittent post-ictal blindness, in which most incidents are sporadic and unrecognized. This study aimed to identify genetic components shared across a local cohort of Arabian foals diagnosed with JIE via a combined whole genome and targeted resequencing approach: Initial whole genome comparisons between a small cohort of nine diagnosed foals (cases) and 27 controls from other horse breeds identified variants uniquely shared amongst the case cohort.
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The Case of Fetal Maceration in Two Different Bitches

Prenatal development consists of three stages in dogs. These stages are called preimplantation, embryonic and fetal period respectively. Embryonic or fetal losses may occur as a result of any causes that damage embryo or fetus during prenatal development period. These losses are called resorption, abortion, mummification and maceration according to the stage of pregnancy. Fetal maceration is often observed in cattle, but also can occur in other domestic animals. The incidence is quite low in bitches. The materials of this case were two bitches in different breeds that are Pointer and Golden retriever. They were brought to Clinics of Obstetrics and Gynecology by their owners with the complaints of growth in their abdomen, increase in weight and decrease in movements at different times. Firstly, detailed anamnesis was taken from their owners. As the mating status of both bitches is unknown, the probabilities of pregnancy and pregnancy pathologies have been neglected in the clinics previously referred to with the same complaints and both bitches were diagnosed with obesity by considering breed predisposition. In this context, it was learned that there was no treatment except for the suggestion of on low energy content foods and exercises however no healthy improvements were observed in both bitches. Gynecological, ultrasonography and radiographic examinations, whole blood and serum biochemistry analysis were performed on both bitches after anamnesis was taken. When the findings of the analysis and examination were evaluated, it was concluded that the fetuses were autolyzed in the uterus without being aborted. It was concluded to perform ovariohysterectomy operation on both dogs for treatment. When the removed uterus tissues were examined, it was seen that both bitches had fetal maceration.
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Late Cerebellar Vermis Metastasis of Breast Cancer Presenting as Pseudo-Benign Paroxysmal Positional Vertigo

Benign paroxysmal positional vertigo (BPPV) is a common peripheral vestibular disease; however intracranial lesions can mimic it. Intractable, not self-limiting paroxysmal positional vertigo sustained by intracranial tumors is called malignant paroxysmal positional vertigo (MPPV) while, when radiological imaging shows vascular cerebellar vermis lesions and there are atypical findings on the Dix-Hallpike maneuver, we speak about pseudo-benign paroxysmal type (pseudo-BPPV).
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Liquid Biopsy in Advanced Gastric Malignancy and Molecular Targeted Therapy; a Case Report and Update Pertaining Anti HER2-Neu Therapy

Human epidermal growth factor receptor 2 (HER2) is responsible for the pathogenesis and poor outcomes of several types of cancers, including advanced gastric and gastroesophageal junction cancer. Molecular-targeted drugs on the other hand, such as trastuzumab, prolong overall survival and progression-free survival in HER2-positive gastric cancer. The purpose of the case report is to evaluate the impact of delivering trastuzumab in advanced gastric cancer with concomitant HER2 mutation and amplification.
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Palatal Rugae Patterns as an Adjuvant to Gender Determination in Forensic Identification Procedures in a Paediatric Population

Identification of an individual who is either living or dead is based on the assumption that all individuals are unique. Whenever an unidentified corpse is found, the individual is classified into characteristic groups and finally the various possibilities are narrowed down.
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Inguinal Lymph Node Squamous Cell Carcinoma of Unknown Primary Site: A Case Report

Carcinoma of unknown primary site (CUP) is a heterogeneous group of malignancies associated with dismal prognosis. Although majority of the patients present with disseminated disease, some of them do present with disease limited to the lymph nodes.
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Responses and Survival under Pegylated Interferon α2a Treatment for Patients with Post-MPN Acute Myeloid Leukemia and Acute Panmyelosis with Myelofibrosis

We report here for the first time the efficacy of pegylated interferon α2a (Peg-Ifn) as a therapy for patients with myelofibrosis and high blast counts. We treated four patients who were in an accelerated phase of myeloproliferative neoplasms or acute panmyelosis with myelofibrosis using only this drug.
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Improvements to In Vitro Culture Media for Use in Bovine IVF

In assisted reproduction of cattle the design and preparation of in vitro culture media has been instrumental in supporting the development of bovine oocytes and embryos. In vitro production (IVP) involves three main sequential steps: oocyte aspiration and in vitro maturation (IVM); in vitro fertilization (IVF); and in vitro culture (IVC) of early pre-implantation embryos.
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Editorial Board Members Related to UV

Huan-Zhang Zhu

Professor
State Key Laboratory of Genetic Engineering
Fudan University
China

Carol A. DeNysschen

Associate Professor
Department of Nutrition & Dietetics
Buffalo State College, SUNY
United States

M Reza Movahed

Professor
Department of Medicine
University of Arizona
USA

Renukaradhya J. Gourapura

Associate Professor
Food Animal Health Research Program,OARDC
The Ohio State University
United States

Hani Mansour

Associate Professor
Department of Water Relations & Field /irrigation
National Research Center
Egypt

MASSIMO RUGGE

Professor
Department of Pathology
Padova University
Italy

Jiang He

Associate Professor
Department of Radiology and Medical Imaging
University of Virginia
United States

Antoine Trzcinski

Lecturer in Water and Environmental Engineering
Faculty of Engineering
University of Southern Queensland
Australia

Shuvra Kanti Dey

Assistant Professor
Department of Microbiology
Jahangirnagar University
Bangladesh

JACQUES MARESCAUX

Professor
Department of Surgery
Research Institute Against Digestive Cancer
France
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