Articles Related to Vitamin D deficiency

Cardiovascular disease (CVD) is one of the most common causes of mortality and morbidity worldwide.Coronary artery disease (CAD) is the most common form of CVD. To prevent CAD we need to assess the risk of future CAD in all patients referred for cardiovascular care, but each of the several available systems for risk assessment has its own limitations. This study was designed to determine whether vitamin D deficiency is a potential risk factor for CAD.

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This study included 75 patients with vitamin D deficiency (group 1), and 25 healthy subjects (group 2). All subjects completed ocular surface disease index (OSDI) questionnaire and underwent to a full ophthalmological examination. The dry eye was assessed in this order: tear break-up time (TBUT), corneal fluorescein staining scoring using the Oxford Schema, and anesthetized Schirmer test (Schirmer II). Measurement of serum 25-hydroxyvitamin D level was done using Enzyme Linked Immunosorbent Assay (ELISA) in the laboratory. All patients were recruited from College of Applied Medical Sciences, King Saud University, and Dwaak Medical Center, Riyadh, Saudi Arabia, by nonrandomized convenience sam¬pling method from February to April 2017.

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Both high prevalence of poor vitamin D status and obesity in children and adolescents are known health problems, but there is not enough information about adequate dose of vitamin D to treat these children.

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The first patient was a 77 year old man who had been on abiraterone for 12 months before his phosphorous was checked. At that point, it was 0.6 mg/dl, which is severely decreased. A full work up for hypophosphatemia showed normal parathyroid hormone and 25-hydroxyvitamin D. A urine study showed inappropriate excretion of phosphorous along with aminoaciduria and normoglycemic glucosuria.

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