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Analysis of antibody by Real-Valued Special Functions

Along with the rapid development of genetic engineering technology and antibody engineering technology, the humanized monoclonal antibody has been rapidly developed and gradually replaces the rat sourced monoclonal antibody. In this paper, we establish two new logarithmically completely monotonic functions involving the real-valued special functions according to two preferred interaction geometries, necessary and sufficient conditions are presented for one of them to be logarithmically completely monotonic. As a consequence, a sharp inequality involving the real-valued special functions is deduced to solve the problems of genetically engineered antibody.
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The Efficacy and Safety of Prophylactic Fluconazole Prevent Invasive Fungal Infection in Preterm Very Low Birth Weight Infants: An Update Meta-analysis

We identified 8 eligible trials that enrolled 1392 infants. There was significant effect of prophylactic fluconazole on fungal colonization (RR, 0.31, 95%C1:-0.24 to 0.41; P<0.00001). Effect of prophylactic fluconazole on IFI in VLBW infants: RR: 0.42(95%CI 0.23 to 0.76; P=0.004.). However, prophylactic fluconazole did not reduce mortality in VLBW infants (RR 0.76, 95% CI 0.58 to 1.01; P = 0.06). Studies did not report significant adverse reactions.
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Communist Extremists, Islamic Supremacists, and Narco-Terrorists: A Forensic Sociological Threat Analysis of Radicalization within the Federative Republic of Brazil

This article presents a human terrain analysis of the Islamic radicalization occurring in Latin America and the infiltration of the Al-Qaeda terrorist network into the country of Brazil. The study used sociological investigative research methods conducted in Brazil, extensive ethnographic interviews collected in the major Brazilian cities of Sao Paulo and Rio de Janeiro, and intensive Brazilian Portuguese language immersion. The ethnographic research techniques examined the social, political, religious, and linguistic structures to gain an understanding of how Al-Qaeda operatives have established an operational base in Brazil. The study provides an early warning sociological intelligence assessment of the threat of radical Islam in Latin America.
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Retrospective Analysis of 185 Occurrences of Clinical Neurological Signs in 181 South American Camelids

Medical records of each occurrence of neurologic signs in 181 South American Camelids admitted on 185 occasions (90 alpacas and 95 llamas) were evaluated. Age ranged from 0 days to 20 years, but 70.5% of cases were ≥ 1 year old. Specific clinical diagnosis was achieved by cerebrospinal fluid analysis (CSF), radiographs, computed tomography, laboratory testing, or necropsy in 74% of cases. 54% of cases survived; 46% of cases died or were euthanized. The most common diagnosis (31%) was parasitic myelopathy/encephalopathy (PME). CSF eosinophilia ≥10% was found in 85% of parasitic spinal migrations but only in 55% of intracranial migrations, and 73% had increased protein in CSF. There was a seasonal bias for PME with 79% of cases occurring between October and March. Survival of PME cases was 77% for spinal migration but only 7% when intracranial migration occurred. The most common diagnoses, excluding PME, were infectious disease (15%) and trauma (12%). Most trauma cases involved the cervical spine of which 50% survived.
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Metaphysical Analysis of the Nutritional and Therapeutic Value of Baobab (Adansonia Digitata L.)

Realistic assessment of the yield and nutritional value of baobab as well as the elucidation of its inhibitory action against oxidative stress were the targets of the study. An average baobab tree can yield 80kg fruits, 14kg pulp, 23kg seeds and 130kg leaves per year. Despite considerable variability, the leaves outstrip in mean Ca (1241 mg/100g dry sample), Fe (40mg/100g dry sample) and ß-carotene (135μg/100g dry sample) content.
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Antrochoanal Polyp Harboring Cholesterol Granuloma: A Case Study

Cholesterol granuloma (CG) is a foreign body reaction to the deposition and inadequate drainage of cholesterol crystals that are frequently found in association with chronic diseases. The clinical symptoms are non-specific. The differential diagnosis of CG includes cysts, mucocoeles and neoplasms. Radiological and histopathological findings are essential for diagnosis of CG. In this report it is aimed to introduce a case of CG in antrochoanal polyp with its clinical and histopathological findings.
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Protocol for Root Canals’ Irrigation in Endodontic Practice in Ivory Coast: A Survey of 100 Dentists

In endodontics, a chemo-mechanical preparation is used to disinfect the root canal system. However, due to limitations of endodontic devices, which shape the main canal, this preparation is supplemented by irrigation solutions. In Ivory Coast, late consultations and advanced stages of pathologies characterized the endodontics.
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Multidimensional LC/MS-MS Analysis of Synthetic Cannabinoids in Urine, Plasma, and Edibles

Synthetic cannabinoids (SCs) present a multitude of problems in terms of maintaining up-to-date methods of detection. They are novel psychoactive substances originally synthesized for medical use and research purposes. Abuse has demonstrated a variety of effects ranging from euphoria to aggressive behavior and death. The marketing, similar naming, and described pharmacological interactions create the dangerous and false perception that SCs are similar to, or the same as, tetrahydrocannabinol in cannabis products
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Quantitative Analysis of Candida Cell Wall Components by Flow Cytometry with Triple-Fluorescence Staining

Detailed analysis of dynamic fungal cell wall components is crucial to our understanding of fungal systematics and the biology and physiology of fungal growth. In fungal pathogens this is of particular importance in examining their response to stress. However, current methodologies do not permit fast and accurate or quantitative analysis of cell wall carbohydrate components. Here, we provide a novel method permitting simultaneous quantitative analysis of the major cell wall components of Candida species relying on triple-staining with fluorescent labeling of chitin, β-glucans and mannans.
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Assessment of Autonomic Function in Subjects Practicing Yoga Using Spectral Analysis and Approximate Entropy Method

Autonomic nervous system involvement in subjects practicing Yoga has rarely been studied and has shown conflicting results. Our main purpose was to assess the effect of Yoga on autonomic function of group of subjects practicing Yoga regularly in comparison with another group with normal control subjects by measuring the frequency gain response of the two groups. Other aim of this study was to determine wither the duration of Yoga practicing correlated with measures of heart rate variability signal (HRV) using approximate entropy index (ApEn).
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Novel analytical technologies of Quality in the Sheep & Goat Dairy Sector

France, Greece, Italy, and Spain the major sheep and goat milk producers in Europe, got the initiative through an interim of 30 years (1985 – 2015), to organize - through IDF - 7 symposiums aiming at the upgrade of the Dairy Sector. One major interest was the milk quality. Stepwise, the efforts followed cow milk structural development in organizing the testing laboratory, the definition of quality in composition (fat, protein, lactose, total solids), in Hygienic (Total Bacteria Count, Somatic Cell Count, antibiotics residues and Aflatoxin M1 contamination), adulteration with water and detection of milk species. EU, by Decision 2002/657/EC, defined the rules for the Directive 96/23/EC, enumerated the testing methods, the demands in sampling procedures, the minimum limits of performance, the quality control (ISO 17025) and the interpretation of results. The equivalency of results from different laboratories, through ISO 17025, demanded the application of ISO analytical standards.
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Bioanalytical Method for Pamabrom (Determined as 8-Bromotheophylline) and its Application to a Pharmacokinetic Study

Pamabrom is a common over-the-counter mild diuretic that is often used in combination with acetaminophen and other drugs for the treatment of menstrual pain. It consists of a 1:1 ratio mixture of 8-bromotheophylline and 2-amino-2-methyl-1-propanol. A bioanalytical method for pamabrom, determined as 8-bromotheophylline, was developed and validated using reverse-phase HPLC coupled with UV detection.
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Gross and Histopathological Alterations in Experimental Trypanosoma Evansi Infection in Donkeys and the Effect of Isometamidium Chloride Treatment

Trypanosoma evansi (T. evansi) infection causes wasting and fatal animal trypanosomosis. This study was aimed at determining the gross and histopathological alterations in donkeys experimentally infected with T. evansi and the effect of isometamidium chloride treatment. Apparently healthy donkeys (N=18) of mixed sexes were randomly assigned to 3 groups; A1 (Infected-untreated), A2 (Infected, isometamidium-treated) and B (Uninfected, control) of six animals each. Each animal in infected groups had about 2.0x106 T. evansi injected through the jugular vein. Parasitaemia levels were evaluated using HCT and Mice Inoculation Test (support test). Gross and histopathological examinations were also conducted post-infection and post-treatment.
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Odontometric analysis of sexual dimorphism in permanent maxillary and mandibular molars

In the field of human osteology, sex estimation is an important step in developing a biological profile. There are a number of methods that can be used to estimate the sex of human remains, varying from visual assessments to metric analysis of sexually dimorphic traits. Teeth are one of the most durable physical elements in the human body and thus can be very successfully used for this purpose. The present study investigates the utility of cervical measurements for sex estimation through discriminant analysis. The permanent molar teeth of 75 skeletons (28 females and 52 males) from the Hasanlu site in north-western Iran were studied. Cervical mesiodistal and buccolingual measurements were taken from both maxillary and mandibular first and second molars. Discriminant analysis was used to evaluate the accuracy of each diameter in assessing sex. The results showed that males had statistically larger teeth than females for maxillary and mandibular molars and cervical mesiodistal and buccolingual measurements (P < 0.05). The range of classification rate was from 78.4% to 87.1% for the original and 78.4% to 85.5% for cross-validated data. The most dimorphic teeth were the maxillary and mandibular second molars, providing 87.1% and 86.1% correct classification rate respectively. The data generated from the present study suggested that cervical mesiodistal and buccolingual measurements of molar teeth can be useful and reliable for sex estimation in Iranian archaeological populations.
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Late Cerebellar Vermis Metastasis of Breast Cancer Presenting as Pseudo-Benign Paroxysmal Positional Vertigo

Benign paroxysmal positional vertigo (BPPV) is a common peripheral vestibular disease; however intracranial lesions can mimic it. Intractable, not self-limiting paroxysmal positional vertigo sustained by intracranial tumors is called malignant paroxysmal positional vertigo (MPPV) while, when radiological imaging shows vascular cerebellar vermis lesions and there are atypical findings on the Dix-Hallpike maneuver, we speak about pseudo-benign paroxysmal type (pseudo-BPPV).
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Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath

The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
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Analysis of Sweat Simulant Mixtures using Multiplexed Arrays of DNA-Carbon Nanotube Vapor Sensors

Carbon nanotube (NT) based electronic vapor sensors were tested against synthetic sweat solutions, consisting of 13 volatile organic compounds (VOCs) in saline, in order to probe the device ability to analyze and differentiate vapors derived from complex biological samples.
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Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS

The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.
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Editorial Board Members Related to anal

LI Liao

Associate Professor
Department of Computer & Information Sciences
University of Delaware
United States

Giorgio Biasiol

Scientist
Institute of Materials
Italy

Yanni Sun

Assistant Professor
Department of Computer Science and Engineering
Michigan State University
United States

Scott Asbill

Professor
Department of pharmaceutics
Presbyterian College School of Pharmacy
United States

Sayed M. Hassan

Senior Research Scientist
University of Georgia
USA

RONALD R. THRASHER

Assistant Professor
School of Forensic Sciences
Oklahoma State University
United States

Lotfi A. Zadeh

Professor Emeritus
Department of Electrical Engineering and Computer Science
University of California
United States

PANKAJ P. KAPUPARA

Associate Professor
School of Pharmacy
RK University
Rajkot
India

XU-FENG HUANG

Professor
School of Health Sciences
University of Wollongong
Australia

Dr. Amarnath Mishra

Assistant Professor
Amity Institute of Forensic Sciences
Amity University
India
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