Articles Related to anemia

Sickle cell anemia is a public health priority, but do its chest manifestations always require a chest radiography ? Our study aims to determine the epidemiological, clinical and radiographic profiles of the thoracic manifestations in the drepanocytic adult in the city of Ouagadougou (BURKINA FASO).

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Infection with Helicobacter pylori(H. pylori) is implicated in iron and vitamin B12 deficiencies without any etiologies. Our prospective study conducted at the Teaching Hospital Yalgado OUEDRAOGO at OUAGADOUGOU (BURKINA FASO) aimed to find a link between H. pyloriinfection and anemia in our context. Patients and Methods:Were selected, patients with iron deficien

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The aim of this study was to assess the potential acute adverse effects associated with the use of anti-glaucoma medications among glaucoma patients with Glucose-6-Phosphate Dehydrogenase deficiency.

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The purpose of this study was to use the computerized database of princess Rahma teaching hospital for children to analyze the prevalence of anemia among children aged 6 months - 12 years attending the emergency room of the hospital.

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Acquired amegakaryocytic thrombocytopenia is an unusual hematological disorder characterized by severe thrombocytopenia in association with a marked decrease, or the absence, of megakaryocytes in bone marrow. Its pathogenesis is not well understood and its clinical course is variable. Several treatments have been used, producing different responses. We present a case that was successfully treated with a calcineurin inhibitor combined with a thrombopoiesis-stimulating agent.

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The London Metropolitan Police in collaboration with medical personnel, study all sudden unexpected death in infancy (SUDI) <2 years in their jurisdiction, to identify suspicious cases for further investigation. The 2005-2010 Project Indigo includes extensive data on all such non-suspicious cases. Deidentified data on age and gender of 477 infants dying a natural unexpected-sudden death in London were gathered for statistical analyses, for comparison to our published a priori probability models that predict their distributions without need of superfluous information, such as race, autopsy findings, or SUDI risk factors. The total observed male fraction of 0.5639 for all these 477 Indigo cases (269 male) is predicted using a recessive X-linkage model for Sudden Infant Death Syndrome (SIDS) as 0.5676. The transformed age distribution of all 477 Indigo cases of different causes of death is modeled by a single four-parameter lognormal distribution, y = Log [(d + 9.44)/(1254 – d)] = μ + σ z, where d is Indigo age in calendar days of life (d = DOD – DOB ≥ 0), median μ = -1.085, slope σ = 0.543, and z is a standard normal deviate.

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Causes of vitamin B12 deficiency in children include decreased intake, abnormal absorption, and inborn errors of B12 transport and metabolism. Rare causes of abnormal cobalamin absorption include Imerslund-Grasbeck syndrome (IGS) and intrinsic factor deficiency (IFD). IGS and IFD are caused by defects in the genes CUBN, AMN, and GIF. We describe a 2 year old male who presented with severe megaloblastic anemia and methylmalonic acidemia. He was found to have a GIF heterozygous mutation c.79+1G>A associated with congenital gastric intrinsic factor deficiency and a novel variant c.960C>A in trans position.

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Sickle cell disease (SCD) is a hemoglobinopathy. Based on genotypes, it is classified into sickle cell thalassemia (SCTh) and sickle cell anemia (SCA).

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Congenital dyserythropoietic anemia type III (CDA III) can be caused by mutation in KIF23. CDA III differs from CDA I and II in the sense that secondary hemochromatosis has not been reported. However, we have observed elevated serum ferritin in a CDA III family.

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Warfarin is the most frequently prescribed oral anticoagulant in the United States. Its indications range from treatment of deep venous thrombosis and pulmonary emboli to the prophylaxis and treatment of thromboembolic conditions associated with atrial fibrillation and cardiac valve replacement. While bleeding is the most commonly encountered complication warfarin induced skin necrosis (WISN) can be a rare complication. Extensive skin and deeper tissue necrosis may be encountered requiring multiple surgical debridement and reconstructive procedures along with the medical management.

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The Health Improvement Network (THIN) provided data from UK General Practitioners (GPs) for 144 pregnant women who were prescribed zanamivir and 144 age- and date-matched untreated comparators with no recorded diagnosis of influenza. Groups were assessed for baseline characteristics, treatment-emergent diagnoses in the mother, pregnancy outcomes and congenital malformations diagnosed in the offspring within 28 days of birth.

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Sarcoidosis is a multisystem granulomatous disease of unknown aetiology. It usually has a benign course, but those cases with multi system involvement have poorer prognosis. Sarcoidosis is an under diagnosed disease in India, probably due to the close resemblance to tuberculosis and the lack of awareness. But this disease is not so rare in India, as previously thought.

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Mycophenolic Acid (MPA) is one of the most widely used immunosuppressive agents in kidney transplantation. This study was designed to compare the safety, tolerability and efficacy of two formulations of mycophenolic acid, Mycophenolate Mofetil (MMF) and Enteric-Coated Mycophenolate Sodium (EC-MPS), in renal transplant recipients.

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