Articles Related to autologous
Hirsutism will be not Considered as Sign of Progressive Disease after Autologous Transplant in POEMS Syndrome
POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes) syndrome is a rare multisystem disease characterized by plasma cell dyscrasia and overproduction of vascular endothelial growth factor (VEGF). Skin changes are usually multiple cutaneous angiomas, leukonychia, necrotizing vasculitis, cutaneous thickening of sclerodermiform type and hypertrichosis. VEGF is assumed to be useful in monitoring disease activity, because VEGF levels usually decrease after treatment. We described the case of a young woman with POEMS syndrome characterized by hirsutism and hypertrichosis who underwent autologous bone marrow transplantation . Evolutionwas hallmarked by an improvment of radiological signs and biological markers specially VEGF, while hirsutism didn’t regress.
Polymorphonuclear (PMN) neutrophil leukocytes are cells of innate immunity recognized in a peripheral blood smear because of their particular multilobed nucleus. Ring shaped nucleous are typical in rats and mice, being described in some pathologies in humans as well as in healthy subjects.
Bone marrow transplant (BMT) recipients often require parenteral nutrition (PN) to meet their nutrient needs. While general guidelines for the provision of PN support by nutrition support teams (NSTs) have been shown to decrease inappropriate PN use, recommendations for nutrition in BMT recipients are lacking.