Top Links

Articles Related to brain

A Case Report of Diffuse Ischemic Injury from Leptomeningeal Midline Glioma Metastases

Diffuse midline gliomas with the histone 3-lysine-27-methionine (H3K27M) mutation should be considered in the differential diagnosis of recurrent hemiparesis and headache in patients with midline brainstem lesions, even with the absence of contrast-enhancement. Early diagnosis is essential for prognostication and engagement in trials evaluating novel therapeutics such as ONC-201.
View complete article: PDF  |  Full-text

Case Report: Severe Sequelae of Sleep Disorders

We report 2 cases of severe injuries in patients with sleep disorders. The first patient sustained multiple orthopedic traumas as sequelae of REM sleep behavior disorders (RBD). The second patient sustained a severe TBI as a result of restless legs syndrome (RLS). To our knowledge, there are only 2 reported cases of severe orthopedic traumas (cervical spine fractures) as a result of RBD and no reported cases of severe TBI from RLS.
View complete article: PDF  |  Full-text

Unexpected Improvement of Chronic Neurological Disease after Recovery from COVID-19 Infection in Four Patients

During the COVID-19 pandemic, physicians actively searched for adverse neurological complications or coagulopathyrelated strokes, but no protective effects were yet reported. We hereby describe our observations at a Geriatrics / Neurology facility on a range of neurological disorders encountered among COVID-19 patients followed for disabling neurological disease (degenerative or post traumatic dementia). We observed a very significant clinical improvement in 4 patients aged 43 to 78, who were in nursing skills home or at home and followed up for a disabling neurological disease for 2 to 5 years. They were affected by COVID-19 between March and October 2020.
View complete article: PDF  |  Full-text

Pathology of Non-Fatal Asphyxia and the Risk of Fatal Outcome in the Context of Intimate Partner Violence

The victims of intimate partner violence are subjected to emotional, physical and/or sexual abuse. The physical abuse often includes episodes of mechanical asphyxia and its most frequent mechanisms: throttling and strangulation. Non-fatal asphyxia situations have signs, symptoms and short-term or long-term consequences whose severity varies according to the intensity, duration and number of episodes.
View complete article: PDF  |  Full-text

Does Obesity Increase the Risk of Brain Damage following COVID-19 Infection?

Neurological impairments associated with Covid-19 have been the subject of numerous investigations since the end of 2019, when the SARS-CoV-2 virus appeared and showed a staggering rise worldwide. Neuroimaging in patients infected with Covid-19 revealed the apparition of severe brain pathologies, such as acute perfusion deficits and white matter abnormalities, meningeal enhancement, basal ganglia lesions, intracranial hemorrhage, encephalitis, cerebral venous thrombosis, encephalopathy, and stroke [1,2].
View complete article: PDF  |  Full-text

Hyperbaric Oxygen Therapy Improves Cognition in Patients Severe TBI; A Prospective Study

Cognitive impairment post TBI is an important factor in rehabilitation outcomes. Pharmacological and therapeutic services do not directly address damage to the cortical infrastructure. Hyperbaric Oxygen Therapy is known to improve brain function and healing.
View complete article: PDF  |  Full-text

Computer Simulations of Brain Oxygenation at the Microvascular Level Validating a New Role of the Arterioles

Brain physiology critically depends on constant oxygen supply to the neurons to ensure various energy–dependent functions of the central nervous system. A volume of latest experimental data on oxygen metabolism obtained with high temporal and spatial resolution, with both invasive and non-invasive methods, and the use of technologies of various degrees of sophistication, strongly suggests arteriole involvement in brain oxygenation. This new approach challenges the traditional views on brain oxygenation according to which oxygen supply to the brain tissues occurs by diffusion at the capillary level.
View complete article: PDF  |  Full-text

After Brain Tumor Surgery: Catheter-Related Bacteremia of Chryseobacterium indologenes Development in Central Nervous System of An Infancy. A Case Report

40-day male infant has admitted to the hospital by family. He has a complaint including lack of suction, vomiting, decreased of movements and continuous sleep about a week of ongoing. Brain computed tomography recognized a mass (with hyperdense hemorrhage) in the posterior fossa and right cerebellar hemisphere.
View complete article: PDF  |  Full-text

Diencephalon-Mesencephalon Dysplasia, with Dysplastic Basal Ganglia, and Midline Fusion, a Case Report of Novel Appearances

Diencephalic-mesencephalic junction dysplasia is a rare malformation characterized by a poorly defined junction between the diencephalon and the mesencephalon, associated with a characteristic butterfly-like contour of the midbrain on axial Magnetic resonance imaging (MRI) sections (butterfly sign). This condition may be variably associated with other brain malformations, including callosal abnormalities and supratentorial developmental hydrocephalus. We report one newborn with third-trimester fetal ultrasound (US) showing ventriculomegaly. After full-term delivery, the baby had microcephaly and generalized hypotonia, and MRI undertaken at age of 5 days, showed features of diencephalic-mesencephalic junction dysplasia (DMJD). The hypothalamic-midbrain fusion and midbrain butterfly sign could have been seen on fetal MRI, thus allowing for the prenatal diagnosis of DMJD, with implications for the surgical management of hydrocephalus and parental counseling.
View complete article: PDF  |  Full-text

Study of Microalbuminuria and its Correlation to Prognosis in Patients with Traumatic Brain Injury: A Longitudinal Study at Level 1 Trauma Centre

Microalbuminuria reflects rapid changes in glomerular permeability and is associated with systemic capillary permeability.
View complete article: PDF  |  Full-text

Novel Computational Model of the Brain Water Metabolism: Introducing an Interdisciplinary Approach

Brain water metabolism ensures the processes of cellular communication, the transit of the signaling molecules, neurotransmitters, cytokines, and substrates, participates in the clearance of pathogenic metabolites. Many neurological conditions that present serious clinical problems arise from the altered fluid flow (e.g. Alzheimer’s disease, idiopathic normal pressure hydrocephalus, migraine, traumatic brain injury and stroke).
View complete article: PDF  |  Full-text

Retrospective Analysis of 185 Occurrences of Clinical Neurological Signs in 181 South American Camelids

Medical records of each occurrence of neurologic signs in 181 South American Camelids admitted on 185 occasions (90 alpacas and 95 llamas) were evaluated. Age ranged from 0 days to 20 years, but 70.5% of cases were ≥ 1 year old. Specific clinical diagnosis was achieved by cerebrospinal fluid analysis (CSF), radiographs, computed tomography, laboratory testing, or necropsy in 74% of cases. 54% of cases survived; 46% of cases died or were euthanized. The most common diagnosis (31%) was parasitic myelopathy/encephalopathy (PME). CSF eosinophilia ≥10% was found in 85% of parasitic spinal migrations but only in 55% of intracranial migrations, and 73% had increased protein in CSF. There was a seasonal bias for PME with 79% of cases occurring between October and March. Survival of PME cases was 77% for spinal migration but only 7% when intracranial migration occurred. The most common diagnoses, excluding PME, were infectious disease (15%) and trauma (12%). Most trauma cases involved the cervical spine of which 50% survived.
View complete article: PDF  |  Full-text

Changes in Several Disease Parameters Including Abzymes and Hematopoietic Progenitor Colony Formation in Brain Inflammation and Demyelination

Demyelination induced by cuprizone-is a widely used experimental model to analyze processes of re- and demyelination in the central nervous system (CNS). Here we used C57BL/6 mice; a model of experimental autoimmune encephalomyelitis (EAE) mimicking important aspects of human multiple sclerosis, to evaluate effects of cuprizone-dependent demyelination on different parameters associated with autoimmune inflammation. The treatment of mice with cuprizone leads to a significant decrease of several indexes characterizing spontaneous and myelin oligodendrocyte glycoprotein (MOG35-55)
View complete article: PDF  |  Full-text

The Importance of Brain MRI in the Diagnosis of Marchiafava-Bignami Disease

Marchiafava-Bignami disease (MBD) is a neurological disorder that has been found to be associated with chronic alcoholism and malnutrition. We report a 45 year old man, chronic alcoholic that developed discouragement for activities involving daily living, changes in retrograde memory in addition to mutism and gait instability. Brain MRI showed central atrophy of the corpus callosum(CC), hypointensity(necrosis) and ventricular dilation(white matter and subcortical region involvement).
View complete article: PDF  |  Full-text

Hypoglossal Schwannoma: A Rare Case Report

Hypoglossal schwannomas are rare cranial base neoplasm arising from schwann cells of the XIIth cranial nerve. We report a case of 45 year old lady with history of headache for 2 years and difficulty in swallowing for 1 year. On evaluation, she was found to have left hypoglossal paresis, atrophy of tongue muscles on left side and a smooth oropharyngeal bulge on left side.
View complete article: PDF  |  Full-text


Editorial Board Members Related to brain

Ramesh C. Gupta

Professor of Chemistry
School of Agricultural Sciences and Rural Development (SASRD)
Nagaland University
India

Alok Dabi

Assistant Professor
Department of Neurology and Neurosurgery
University of Texas Medical Branch (UTMB)
United States

CHRISTOPHER THOMAS WHITLOW

Associate Professor of Division of Radiologic Sciences
Department of Radiology
Wake Forest School of Medicine
United States

Amolak Singh

Professor
Department of Radiology
University of Missouri Health Care
United States

CHIA-YI KUAN

Associate Professor
Department of Pediatrics
Center for Neurodegenerative Disease
Emory University School of Medicine
United States

Wei-Yen Hsu

Professor
Department of Information Engineering and Management
National Chung Cheng University
Taiwan

Alain L Fymat

President/CEO and Professor
International Institute of Medicine and Science
Rancho Mirage
California
USA

Keyvan Mostofi

Department of Neurosurgery
University of UCL
France

Huan-Zhang Zhu

Professor
State Key Laboratory of Genetic Engineering
Fudan University
China

Eric Fung

Professor of Pharmacology
Department of Oral Biology
University of Nebraska Medical Center College of Dentistry
United States
Submit Manuscript


Open Access Journals

View All Journals