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Articles Related to cancer

The Use of Cardiac Resynchronization Therapy in Cancer Patients with Heart Failure

Investigate the use of cardiac resynchronization therapy (CRT) in cancer patients with heart failure (HF); assess factors associated with ischemic and non-ischemic HF. Many newer cancer therapies are cardiotoxic; thus, the incidence of HF has been increasing in this high-risk patient population. CRT has beneficial effects on morbidity, mortality, and left ventricular function in patients with non-ischemic cardiomyopathy, yet cancer patients and survivors who develop severe HF and are eligible for CRT often does not receive it.
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Immune Checkpoint and Ovarian Cancer

Many scientists and biotechnology companies had given up on the idea of cancer immunotherapy in 1990s. Almost a decade after first detection of T cell suppression effect of CTLA4 the identity of its antibody was established. While they are found effective in many cancers including melanoma, lung cancer etc. immune checkpoint inhibitors have lent an important measure to manage recurrent and refractory ovarian cancer. This subject needs constant updating specially for students of ovarian cancer who are looking at this avenue of cure with much hope.
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Advances in the Treatment of Breast Cancer-Emphasis on fertility preservationA Case Report

With the recent advances in breast cancer treatment the 5 year survival rates have increased significantly with overall 20yrs survival in developed countries like USA. With further improvement being designed in the treatment of breast cancers with more and more sophisticated models to study breast cancer in human beings using the modern microfluidic models one expects more and younger breast cancer survivors to be needing fertility treatments. Here we review the modern advances in breast cancer treatments and the need for emphasizing on fertility preservation before starting any chemotherapeutic or other management as recommended by both ASO and ASRM.
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Late Cerebellar Vermis Metastasis of Breast Cancer Presenting as Pseudo-Benign Paroxysmal Positional Vertigo

Benign paroxysmal positional vertigo (BPPV) is a common peripheral vestibular disease; however intracranial lesions can mimic it. Intractable, not self-limiting paroxysmal positional vertigo sustained by intracranial tumors is called malignant paroxysmal positional vertigo (MPPV) while, when radiological imaging shows vascular cerebellar vermis lesions and there are atypical findings on the Dix-Hallpike maneuver, we speak about pseudo-benign paroxysmal type (pseudo-BPPV).
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Challenges in the Pharmacological Management of Non Hodgkin’s Lymphoma in Children in the Maintenance Phase of Therapy at Kenyatta National Hospital

Non Hodgkin’s lymphoma is an extremely chemo sensitive with a five year event free survival of greater than 90% in developed countries and a one year survival rate of 40-50% in developing countries.
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Retinoblastoma: A Retrospective Study of 27 Cases in University Hospital of Lubumbashi-RDC

We conducted a retrospective study on 27children with retinoblastoma in the Lubumbashi University Hospital between January 2008 and October 2012. Al cases were diagnosis clinically and 11 cases were confirmed by histology.
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Pulmonary Adenocarcinoma Transforming into Small Cell Carcinoma: An Extreme Rarity

Primary small cell lung cancer (SCLC) showing epidermal growth factor receptor (EGFR) mutation is extremely rare. Transformation into SCLC has been reported as an evolution of lung adenocarcinoma acquiring resistance to EGFR tyrosine kinase inhibitors (TKI) and is considered to be a rare resistance mechanism of EGFR-TKI therapy.
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Paediatric Radiotherapy in Morocco

In Morocco, through the finding of the Casablanca population-based registry, all cancers are estimated at 35000 new cases par year and 3.2% are aged less or equal 20 years.
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Awareness of Cervical Cancer Risk Factors, Screening Practices and Attitudes among Nurses in a Primary Health Care Setting of Morocco: A Cross-Sectional Study

The effectiveness of the cervical cancer screening activities depends on physicians and nurses’ level of awareness and their adherence to the program.
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Liquid Biopsy in Advanced Gastric Malignancy and Molecular Targeted Therapy; a Case Report and Update Pertaining Anti HER2-Neu Therapy

Human epidermal growth factor receptor 2 (HER2) is responsible for the pathogenesis and poor outcomes of several types of cancers, including advanced gastric and gastroesophageal junction cancer. Molecular-targeted drugs on the other hand, such as trastuzumab, prolong overall survival and progression-free survival in HER2-positive gastric cancer. The purpose of the case report is to evaluate the impact of delivering trastuzumab in advanced gastric cancer with concomitant HER2 mutation and amplification.
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Treosulfan Plus Fludarabine – Encouraging Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Multiple Myeloma

Allogeneic transplantation (Allo-SCT) in multiple myeloma is controversial mainly due to the relatively high non-relapse mortality (NRM). The aim with this retrospective single-center study was to evaluate recent transplants particularly after conditioning with treosulfan plus fludarabine (TreoFlu).
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Breast Cancer Detection by Determination of Optical Properties of Non-Malignant and Malignant Breast Tissues

Breast cancer being one of the most frequent form of cancer, is the leading cause of cancer deaths in women worldwide. Early detection can greatly improve a woman`s chances for survival. In this paper we introduce an economic and accurate optical system for breast cancer detection.
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Effect of Neoadjuvant Chemoradiotherapy on Pathologic Stage and Survival in Patients with Locally Advanced Esophageal Cancer

The treatment of resectable stages of esophageal cancer often involves pre-operative concurrent chemoradiotherapy. This study aims to evaluate the effect of cisplatin/5-fluorouracil (5-FU)-based neoadjuvant chemoradiotherapy on pathologic stage and survival in patients with locally advanced esophageal cancer.
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Gastroesophageal Cancer: Prognostic Factors and Treatment Results

The study presents the remote results of surgical treatment of 329 patients with cancer of gastroesophageal localization. Three 3-year survival rate is 37.1%, the 5-year survival rate is 26.2%. Prognosis after the surgery depends primarily on the extent of the tumour spread.
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Age Adjusted Charlson Comorbidity Index: Predictor of 90-Day Mortality after Radical Cystectomy

To evaluate the impact of age adjusted Charlson’s comorbidity index (ACCI) in predicting 90-day mortality in patients undergoing radical cystectomy for Muscle Invasive Bladder Cancer (MIBC) in a low volume center.
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Editorial Board Members Related to cancer

Jason X. Cheng

Assistant Professor
Department of Pathology, Hematopathology
University of Chicago
United states

ADELIA C BOVELL-BENJAMIN

Professor
Department of Food and Nutritional Sciences
Tuskegee University
United States

P. S. SURESH

Assistant Professor
Department of Bio-Sciences
Mangalore University
India

Fuu –Jen Tsai

Professor
Department of Medical Genetics
School of Chinese Medicine
China

Daniela Iannazzo

University Researcher
Department of Electronic Engineering, Industrial Chemistry and Engineering
University of Messina
Italy

K. RAMANATHAN

Associate Professor
Industrial Biotechnology Division
School of Bio Sciences and Technology
VIT University
INDIA

Suzanne M. Miller

Professor
Division of Cancer
Fox Chase Cancer Center
United States

HELENA MALTEZOU

Paediatrician
Hellenic Centre for Disease Control and Prevention
Athens
Greece

Hui-Fen Wu

Professor
Departmant of chemistry
National Sun Yat-Sen University
Taiwan

NATASHA TASEVSKA

Assistant Professor
School of Nutrition and Health Promotion
Arizona State University
United States
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