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Articles Related to cancer

How Nurse Education Impacts Her Career?

A great proportion of healthcare services need high-quality medication and nursery. For high-quality nursery needs best nurses and their education. Gradually, different types of nursery education systems can impact their life and career. In the future, more parameters can be used for judging the quality and promotion of nurses. This editorial addresses different educational efforts for their progresses in medical knowledge promotion, technical capability improvement and salary promotion.
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Sysmex UD-10 should Accompany UF-5000 in Managing Atypical Cells in Urine

Sysmex UF-4000/5000 uses fluorescence flow cytometry technology and hydrodynamic focusing for urine sediment analysis, where particles are stained by specific fluorochromes for nucleic acids and surface structures and then sent through the semi-conductor laser beam. Atypical cells show side fluorescence and scattered light properties indicating their enlarged nuclei and increased nucleus/ cytoplasm ratio
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Exhaled Volatile Organic Compounds in Patients with a Medical History of Cancer/Dysplasia

Exhaled Volatile Organic Compounds (E-VOCs) have been associated with cancer and may help to early detection or even identify pre-cancerous status.
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Application of the Posterior Approach Technique in Laparoscopic Radical Hysterectomy for Cervical Cancer

The aim of this study was to compare and determine the feasibility, surgical outcomes, intraoperative and postoperative complications of the use of the posterior approach technique in the laparoscopic radical hysterectomy (LRH) to the conventional laparoscopic radical hysterectomy in patients with cervical cancer.
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Cranial Vault Tumor Revealing Metastatic Thyroid Carcinoma

Distant metastases from follicular thyroid carcinoma are not uncommon, but bone localization in the cranial vault is extremely rare. Although these metastases have a poor prognosis, early diagnosis and appropriate treatment can improve quality of life. We report a case of follicular thyroid carcinoma revealed by a metastasis of the cranial vault initially diagnosed as meningioma.
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Oral Carcinoma in Young-Clinico-Pathological Profile and Survival Outcomes in a North Indian Population

To study the prevalence, clinico-pathological profile and survival outcome of oral squamous cell carcinoma in young patients (<40 years).
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Multiple Sclerosis Disease Modifying Therapy and Cancer risks

Multiple sclerosis (MS) is a chronic inflammatory condition not commonly associated with cancer. Although since 1993 with the introduction of disease modifying therapies (DMTs), changing the natural history of the disease, cancer risk appears associated with some of these new therapies. We present the most common risks associated with each DMTs.
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Drug Therapy Problems and Clinical Outcomes Among Patients with Human Epidermal Growth Factor Receptor 2 (HER2) Positive Breast Cancer on Trastuzumab-Based Therapy in a Kenyan Tertiary Health Facility

Breast cancer ranks first among the most commonly diagnosed cancers in Kenyan females and globally. Treatment is challenging because it is a heterogeneous disease with several subtypes. There has been a significant change in the treatment of Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer subtypes following the introduction and widespread use of HER2 targeted therapies.
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Clinicopathological and Prognostic Value of Plasmacytoid subtype in Bladder Cancer: A Systematic Review and Meta-Analysis

The World Health Organization, in 2004, published a new classification that recognizes different histological variants (HV) of urothelial carcinomas
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A Screening Study of Cervical Cancer Using Pap Smear Test in Outpatient Clinic of Must University Hospital

Despite the well-established importance of early cervical cancer detection, there are no clear data about the prevalence of cervical intraepithelial lesions among Egyptian population due to lack of screening programs. Thus, we conducted this study in order to assess the prevalence of inflammatory, premalignant and malignant cervical lesions among Egyptian population using Pap smear test.
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Cost-Effectiveness and Budget Impact Analysis of Recombinant Tumor Necrosis Factor-Thymosin Alpha 1 in a Complex Treatment of Metastatic Breast Cancer

Recombinant tumor necrosis factor -thymosin alpha 1 (TNF-T) has been used in Russian oncological practice for a number of years.
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Predictive Value of ERCC1 Expression on Treatment Response to Cisplatin-Based Regimens in Small Cell Lung Cancer: A Retrospective Analysis

We aimed to determine whether the excision repair cross-complementation group 1 (ERCC1) expression predicts response to cisplatin-based chemotherapy in patients with small cell lung cancer (SCLC). This was a retrospective study, in which hospital files of 31 patients (29 males, 2 females; mean age, 62.26±7.71 years) were reviewed. All patients were treated with etoposide+cisplatin. The lung biopsy and mediastinal lymph node samples were applied anti-human monoclonal antibodies against ERCC1: immunohistochemical staining was considered positive if 25-100% of the cells showed nuclear staining, and negative if less than 25% of the cells showed negative or slight staining. Response to treatment was evaluated as regression (complete or partial response), progressive disease, or stable disease. Of the patients, 18 (58.1%) had limited-stage, and 13 (41.9%) had extensive-stage SCLC. Median follow-up duration was 15 months (range: 1-60 months). ERCC1 staining was positive in 9 of 31 patients (29.0%). In 12 patients (38.7%), tumor regression (complete or partial response) was obtained after chemotherapy. Tumor regression rate was higher in ERCC1 positive patients than those with negative ERCC1 expression (66.7% vs. 27.3%, p=0.036). In conclusion, high expression of ERCC1 was associated with higher response rate to cisplatin-based regimens in patients with SCLC.
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Monoclonal Antibodies for the CIGB-552 Antitumor Synthetic Peptide Quantification

The CIGB-552 peptide is a synthetic peptide that exerts cytotoxic effect on tumor cells. Thus, CIGB-552 peptide quantification in patient samples is crucial for assessing the treatment efficacy. Therefore, this study describes the generation and characterization of monoclonal antibodies (mAb) directed against the CIGB-552 peptide to be used in a quantification assay in further pharmacokinetic studies in humans. In this sense, the CIGB.552-H294 mAb specificity was evidenced only against the CIGB-552 peptide and a metabolite of 17 amino acids resulting from the CIGB-552 peptide degradation detected in mouse sera.
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Profile of Tumor-Associated Cytokines among Breast Cancer Patients: A Preliminary Study

The link between disease and the oral cavity represent clinically important factors that have given rise to the interest in using saliva as a diagnostic fluid for systemic diseases. The objective of this study was to detect and quantify cancer related cytokines in the saliva of women with breast cancer and compare their concentrations to a healthy cohort.
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microRNA 181a-5p Reprogramed Glucose and Lipid Metabolism in Non- Small Cell Lung Cancer

microRNAs play critical roles in cancer metabolisms. miRNA-181a-5p is significantly down-regulated in non-small lung cancer tissue and mesenchymal like lung cancer cells. Epithelial-mesenchymal transition mechanisms and cancer metabolism are controlled by the same signaling pathway.
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Editorial Board Members Related to cancer

XIAOYANG QI

Associate Director
Division of Hematology-Oncology
Department of Internal Medicine
University of Cincinnati
United States

Jianfei Qi

Assistant Professor
Biochemistry and Molecular Biology
University of Maryland School of Medicine
United States

Kwang-Hyun Baek

Department of Biomedical Science
CHA University
Republic of Korea

Saeid Abroun

Associate Professor
School of Medicine
Tarbiat Modares University
Iran

Rammurti T. Kamble

Professor of Medicine
Baylor College of Medicine
United States

Mridula Chopra

Senior Lecturer
School of Pharmacy and Biomedical Sciences
University of Portsmouth
United Kingdom

Eugene S. Kim

Associate Professor
Department of Surgery
University of Southern California
United States

Michael Gibson

Associate Professor
Department of Medicine
Case Western Reserve University
United States

KELLI BULLARD DUNN

Professor
Department of Surgery
Roswell Park Cancer Institute
University of Louisville School of Medicine
United States

ROBERT TODD STRIKER

Associate Professor of Medicine
Department of Microbiology and Immunology
University of Wisconsin
United States
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