Articles Related to children and adolescents
Immunological Analysis of Active Tuberculosis Infection in Children and Adolescents
The latent tuberculosis infection worldwide is determined by about 1.7 billion people. Identification of latent tuberculosis infection and prevention of the development of the disease is one of the highest priority tasks in the global radical reduc- tion of the burden of tuberculosis. The research is devoted to the study of the effectiveness of cellular and humoral anti- gen-specific immunological methods for determining the initial signs of tuberculosis infection activity when examining children and adolescents with a latent form of this infection. Cellular immunological reactions in contrast to the determi- nation of specific antibodies of blood serum using the recombinant specific protein ESAT-6-CFP-10, were not sufficiently effective in differentiating active and latent infections.
Determination of antibodies to the ESAT-6-CFP-10 protein with analysis of the specific activity criterion and determina- tion of an increased concentration of neopterin up to 9 nM/L in blood plasma samples made it possible to reveal signs of tuberculosis infection activity. These results have been confirmed by the results of chest computed tomography of children and adolescents with the determination tuberculosis of intrathoracic lymph nodes or small intrapulmonary (2-5 mm) intrapulmonary foci, including those with signs of calcification.
Transversal Pertussis Sero-Epidemiological Study in Fully Vaccinated Children and Adolescents in Antananarivo, Madagascar, and in Dapaong, Togo
African region is thought to contribute to >50% of deadly cases of pertussis worldwide, however surveillance and available data on Bordetella pertussis circulation are limited. Currently, pertussis vaccination schedule in most African countries is restricted to a primary immunization consisting of three doses during the first year of life using whole
pertussis vaccines for which effectiveness is not known.
Decision-making in the Management of Badly Decayed First Permanent Molars in Children and Adolescents
To report the decision making in management of badly decayed First Permanent Molars (FPMs) in children and adolescents among clinical consultants (specialists) and pediatric dentists at King Abdulaziz University (KAU), Faculty of Dentistry, Jeddah, Saudi Arabia.
Treatment of vitamin D deficiency in children and adolescents
Both high prevalence of poor vitamin D status and obesity in children and adolescents are known health problems, but there is not enough information about adequate dose of vitamin D to treat these children.
Editorial Board Members Related to children and adolescents
Sheila Barrett
Assistant Professor
Department of Nutrition
Northern Illinois University
United States
Department of Nutrition
Northern Illinois University
United States