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Articles Related to cocaine

Drugs of Abuse and Addiction - Overview and Current Status

Today, both nonprescription and prescription drugs used by people for disease treatment, illicit or reward purposes have diverse effects on health permanently or long-lastingly. The effects may even continue and lead to the death or disabilities in child when a person is no longer use the substance. Substances that cause addiction trigger intense feeling of euphoria then lead to loss of control of self-behavior and perception.
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Superior Mesenteric Artery Embolus as a Delayed Complication of a Cocaine Induced Myocardial Infarction

Cocaine has acute and chronic effects on health as well as addiction and dependence and places a significant burden on healthcare systems. After cannabis, it is the most frequently used illicit drug worldwide. It is estimated that between 14 and 21 million people use the drug each year [1]. Its main adverse effects occur in the cardiovascular system. Cocaine causes sympathomimetic actions such as tachycardia, hypertension and coronary artery constriction due to enhancement of release of catecholamines. It enhances thrombus formation by activating platelets and potentiating thromboxane production [2]. The consequences of these effects include chest pain, myocardial infarction, aortic dissection, coronary artery aneurysm, myocarditis, cardiomyopathies and arrhythmias. Our case demonstrates a young patient who had a delayed presentation of a myocardial infarction, in the setting of recent cocaine use that was complicated by an apical thrombus which resulted in distal emboli to his superior mesenteric artery and left renal artery. It highlights the fact that in a young patient with no other risk factors how complications may arise, even weeks after cocaine use.
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Elective Anesthesia and Surgery in Veteran Patients Abusing Cocaine - Factors Influencing Management Decisions

Cocaine abuse remains to be a significant anesthesia challenge making decision to proceed with anesthesia in patients in general and veterans in particular testing positive for cocaine quite controversial.
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Quantitative Analysis of 30 Drugs in Whole Blood by SPE and UHPLC-TOFMS

An Ultra-High Pressure Liquid Chromatography Time-of-Flight Mass Spectrometry (UHPLC-TOF-MS) method for quantitative analysis of 30 drugs in whole blood was developed and validated. The method was used for screening and quantification of common drugs and drugs of abuse in whole blood received from autopsy cases and living persons.
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