Articles Related to diabetic patients

Background and Objective: In Cameroon, given the galloping growth in the prevalence of diabetes, in particular type 1 diabetes in the northern regions, we undertook this study, with the objective to improve the management of type 1 diabetes by determining the socio-demographic, clinical characteristics and lipid profiles of the patients followed in the care centers of regional hospitals of Maroua, Garoua and Ngaoundere. Methods: We undertook a descriptive cross-sectional study from 07 August 2018 to 07 May 2019 in the care centers of the regional hospitals. Sociodemographic and clinical data were collected by interview to consent patient through structured questionnaires in the survey sheet. Anthropometric data were also determined during the survey, and the blood was collected in referred laboratory for determination of some lipid profiles parameters. Results: On a sample of 467 Patient suffering from diabetes, 68 were of type 1, representing a prevalence of 26%. Type 1 diabetes Patients were mostly female (61.8%) and the mean age was 20.72 ± 3.4 years with a high percentage between 20-30 years (51.5%). More than half of our patients were pupils and students, many of them practiced Muslims as religion (58.8%). In most of cases (51.3%), the disease was diagnosed after one year as a result of illness. The majority of our patients were non-smokers (98.5%) and less athletic (32.4%). The mean Body Mass Index (BMI) was 23.03 ± 2.7 kg /m2 with an average waist circumference of 80.26 ± 9.23 cm in men and 82.15 ± 10.45 in women. Their treatment was based essentially on insulin therapy, mainly using regular and intermediate insulins. More than half of the subjects had high blood glucose (78.1%), high triglyceride (34.1%) and HDL-cholesterol (29.3%) levels. Most of the patients suffered from overweight/obesity, high blood pressure, arthritis, kidney failure and other diseases (malaria, jaundice, stomach ache). No significant relation was found between clinical and the sociodemographic and blood lipid profiles. Conclusion: It emerges from this study that type 1 diabetes represent high proportions of diabetes cases in septentrional area of Cameroon, and affect mostly young of less than 30 years old, dominated by women, practicing Muslim as religion. Their clinical profile characterized by high frequency of overweight/obesity, kidney failure and arthritis vary, but not significantly, with neither their sociodemographic nor their blood lipid profiles. Absence of sport, female and less control of their hypoglycemia are factors risks of the progression of the disease.

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Fasting from dawn to dusk during Ramadan is obligatory for all healthy adult Muslims.

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Human islet amyloid polypeptide (hIAPP), a 37 residue peptide hormone is an ingenious factor in pancreatic amyloid deposits found in cases with type-2 diabetes. Its aggregation into small toxic oligomeric species is presumed to be the reason for cells debilitation and demise in case of diabetic patients.

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