Articles Related to diagnostic

Pancreatic cancer carries one of the worst prognoses in the United States. It is the fourth leading cause of cancer-related death in the United States and second after colorectal cancer in digestive system cancer-related death. Early detection is the key to improving its prognosis. Surgical resection is the only curative treatment, but even after margin-negative resection, the 5-year survival rate is still 30%. The following case presents a fascinating diagnosis of pancreatic cancer. Despite an initial diagnosis of pancreatitis, negative cytology, tumor markers, and imaging suggestive of intraductal papillary mucinous neoplasm (IPMN), this patient underwent surgical resection that later revealed pancreatic adenocarcinoma of the tail. This article highlights certain imaging modalities and characteristics that are essential in the diagnosis of pancreatic adenocarcinoma, in an effort to guide management of similar cases, with hope it leads to better outcomes.

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Forty patients with CHDs who received liver biopsy to stage fibrosis and 12 normal subjects performed also shear wave elastography (SWE) and ELF-test. We chose two different outcomes for histological fibrosis (F0-F1 vs F2-F4) and (F0-F2 vs F3-F4). ELF-test and SWE were independent predictors, categorized using ROC analysis. Two scores called SCORE1 and SCORE2 were devised.

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Haemangiomas are the most common benign incidentally detected hepatic lesions with a prevalence of ~20%. Most of them have typical imaging features and are easily diagnosed on triple phase studies. These are capillary, flash and giant hemangioma. Another subset of haemangiomas are Sclerosing hemangiomas or atypical haemangioma; these are sclerosed, thrombosed and/or hyalinised due to which these are heterogenous and show varied appearance making them difficult to diagnose.

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To adapt the perfusion-CT (PCT) examination-protocol in patients with liver cirrhosis and suspected hepatocellular carcinoma (HCC) while keeping diagnostic accuracy and qualitative assessment of tumor enhancement patterns (wash-in/wash-out) at comparable radiation dose.

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The emergence of SARS-CoV-2 variants raises increasing concerns about the efficacy of currently available vaccines [1]. mRNA vaccines (BNT162b2, Pfizer-BioNTech; mRNA-1273, Moderna) are developed based on one specific part of the viral genome to elicit immune response. Therefore, they might be susceptible to immune escape mutations, such as the ones in the viral Spike protein [2].

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Multiple myeloma is the second most common onco-hematologic neoplasm, accounting for 1% of malignant neoplasms. It is an underdiagnosed condition, as well as herpetic encephalitis.

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Undetected colonic polyps are considered a major cause of interval cancer of the colon. The Automatic Polyp Detection System (APDS) (Magentiq Eye LTD, Haifa, Israel) was developed to enhance the ability of endoscopists to detect polyps during screening colonoscopy. It is designed to be used both in real-time and offline. APDS runs directly on the video output of the endoscopic camera and highlights the polyp on the screen. APDS utilizes the power of Deep Learning and Computer Vision in order to improve polyp detection rates thus improving the performance of the endoscopist.

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Undetected colonic polyps are considered a major cause of interval cancer of the colon. The Automatic Polyp Detection System (APDS) (Magentiq Eye LTD, Haifa, Israel) was developed to enhance the ability of endoscopists to detect polyps during screening colonoscopy. It is designed to be used both in real-time and offline. APDS runs directly on the video output of the endoscopic camera and highlights the polyp on the screen. APDS utilizes the power of Deep Learning and Computer Vision in order to improve polyp detection rates thus improving the performance of the endoscopist.

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Hydatid disease is an important emerging neglected disease worldwide, with significant geographic variation in seroprevalance. The disease is commonly diagnosed on basis of clinical suspicion, imaging and serology. This study was conducted to evaluate our experience with serology in diagnosing hydatid disease in terms of identifying the numbers of patients testing positive for antibodies against Echinococcus, and to study their clinical profile.

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Giant cell arteritis (GCA) requires prompt diagnosis as clinical indicators of GCA are non-specific. Temporal artery biopsy (TAB) can be inconclusive and difficult to arrange timely. MR imaging is accurate for showing vessel thickening. However, the availability of MRI remains an issue in many radiology departments.

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Candida, a commensal of the oral and the vaginal cavity, sometimes turns invasive, in immunosuppressed individuals. The resultant lesion, known as invasive or aggressive candidiasis, can be extremely refractory to treatment. This is a case report of an ulcero proliferative lesion in the hard palate that mimicked an intra-oral neoplasm. The clinical picture was confused by the fact that the patient was a chain smoker, and also because the initial MRI images were strongly suggestive of an invasive malignancy. When clinical and radiological signs exactly mimic a malignancy, the picture is confusing.

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A 62-years-old female patient with a diagnosis of conversion disorder and somatization disorder and a 20-years-old female patient with a diagnosis of conversion disorder were treated on electroconvulsive therapy. Electroconvulsive therapy was performed in 8 sessions with anaesthesia. 62-years-old patient began to recover after the sixth session of electroconvulsive therapy once every two days. Complete remission in catatonic symptoms also sustained during follow-up. The catatonic symptoms of the 20-years-old patient were completely terminated after the second session of the ECT once every two days. The treatments were completed in 8 sessions.

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A variety of agents are used during any surgical procedure to control intraoperative bleeding. Most of them are meant to be removed at the end of the procedure. Sometimes these are accidentally forgotten at the operative site which may present with different clinical symptoms subsequently.

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Osteoid osteoma (OO) is a benign bone tumour. In 1935, the jaffe reported it first. The fifty percent of OOs occur in long bones of the lower extremities but it may affect any bone. Only 1 % OOs affects the ribs and surgical excision was reported only in 14 cases in the literature. Complete surgical excision is the standard treatment method for osteoid osteoma is complete surgical excision which is reserved for the patients not responding to conservative treatment. In this report, we present a case of osteoid osteoma of the posterior part of the shaft of the sixth rib affecting a 30-year-old male, who had presented with symptoms of severe pain over the affected area and underwent surgical resection. Excised rib segment showed no osteosclerotic lesion on X-ray so immediately extended resection of the sixth rib was done. Here we have tried to evaluate the importance of the presence of the skeletal scintigraphy or C Arm image intensifier intraoperatively by comparing our experience with the available literature.

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The comorbid psychopathology that is well-established in ethnoracially diverse OEF/OIF/OND veterans also often coincides with other problems (e.g., legal and social). To mitigate the clinical side of these types of difficulties, the Veteran Administration Health Care Systems offers a wide range of mental health services. This article draws on an evidenced-based literature review to explore factors that are relative to delivering group psychotherapy in light of the entwined clinical and forensic matters sometimes confronting diverse veterans.

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The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.

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