Articles Related to disease
The cause of Alzheimer's Disease & Relative Dementias is Brain Information Processing Impairments
In the last decade, neurodegenerative diseases (such as Alzheimer's disease, Parkinson's disease, and various forms of Dementia) have become a challenging problem facing contemporary society, placing on it a strong economic, social, and
healthcare burden. Despite huge and long-lasting efforts, the progress in solving these problems remains unsatisfactory
Transgenic Expression of Sugarcane Mosaic Virus VPg in Maize Inbred Line CML444 Confers Resistance to Maize Lethal Necrosis Disease
Maize is the most important crop in Kenya and parts of Sub-Saharan Africa. However, yields are below potential due to abiotic and biotic constraints. One of the major biotic concerns is maize lethal necrosis disease (MLN), which causes up to
100% yield losses. MLN is caused by the synergistic infection of two viruses, Maize chlorotic mottle virus (MCMV) and a potyvirus, commonly Sugarcane mosaic virus (SCMV)
A Single-Center Experience in Alport Syndrome
Alport Syndrome is a hereditary condition that affects the collagen in the basement membrane and is characterized by microscopic hematuria, sensorineural hearing loss, increasing renal dysfunction, and ocular abnormalities. It is
more common between the ages of 20 and 30. Men and women are equally affected. However, the prognosis of men is
worse than women due to renal failure. The purpose of this study is to evaluate the demographic and clinical findings of patients with Alport Syndrome in our center
The Challenge of Rapid Data Collection and Health Promotion: A Quick and Easy Approach
Rapid data collection can provide an insight into causation, the socio-cultural reality, and complex social processes. This is
especially important in disease outbreaks when information is quickly required on local needs that is essential for success.
Quantitative data alone are not sufficient to provide an in-depth understanding. The challenge is to use a rapid data collection
approach that can provide practical solutions by integrating the available evidence, professional expertise, and stakeholder
experiences. This viewpoint reflects the opinions of the author that highlight the strengths and weaknesses of rapid
data collection and the presentation of an approach that can be implemented with minimal interference in a health promotion
and healthcare program context
Case Report: Pyoderma Gangrenosum in IBD Treated with Tofacitinib
Pyoderma gangrenosum is a rare ulcerating skin disease often presenting as an extra intestinal manifestation of IBD and is
difficult to manage. Treatment options for pyoderma gangrenosum include steroids, calcineurin inhibitors and anti TNF
agents. Here in, we report a case of recurrent Pyoderma gangrenosum with Ulcerative Colitis that was successfully managed
with Tofacintib, a JAK inhibitor
Effect of Pesticides on Human Health
The demand for pesticides has increased in today's world of expanding population in order to boost crop productivity and
eliminate undesirable plants (weeds) that grow alongside the primary crop.
Study to Find Clinical Characteristics of ABPA in Patients of Severe Bronchial Asthma and Its Relation with Serum Ige Level at Teriary Care Center North India
Allergic bronchopulmonary aspergillosis (ABPA) is an idiopathic inflammatory disease of the lung, characterized by an allergic inflammatory response to colonization of the airways by Aspergillus fumigatus or other fungi. Untreated
or inadequatetreatment may lead to poor outcome in patients. Raised level of serum IgE of more than 1000 IU/ML have
been considered as one if theimportant diagnostic criteria for ABPA, however relation of serum IgE withs severity ofdiseases is lacking. This study was conducted to find out level of serum IgE in patients ofABPA and to find out corelation of
Serum IgE with duration of symptoms and diseasesseverity.
Review on MALDI TOF MS: Modern Disease Diagnosis Approaches in Microbiology and its Mechanism
Matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) has become a widely used technique for the rapid, accurate, durable, economical, and trustworthy method for identification of bacteria, mycobacteria and fungal pathogens in the microbiology laboratory.
Right Atrial Myxoma with Critical Triple Vessel Disease: A Case Report
Cardiac myxoma are the most common primary heart tumor. It accounts for 40-50% of primary cardiac tumor. Approximately 75% occurs in left atrium and 15-20% in right atrium. Myxoma are usually polypoid, pedunculated lesion with smooth surface covered with thrombus. Most common site of attachment is at the border of fossa ovalis in left atrium but it can occur in any part of atrial wall. Symptoms are produced because of mechanical obstruction with cardiac blood flow, tumor embolization and constitutional symptoms due to increased expressions of IL-6. Echocardiography is the best diagnostic modality to localise the tumor. Surgical excision is the mainstay of treatment of myxoma present in any location.
Mathematical Modeling of Pathological Processes in Alzherimer’s Disease
Using kinetic differential equations and the Runge-Kutt algorithm, an analysis of the pathological processes occurring in the course of Alzherimer’s disease was carried out. Thanks to the appropriately selected kinetic equations, the presented model allows to explain the time course of the growth of pathological proteins: beta-amyloid and tau protein and the related loss of nerve cells. The model is based on previous experimental knowledge of Alzherimer’s diseas and is in good agreement with the experimental data.
A Case Report of ST-Segment Elevation Myocardial Infarction With Non-Obstructive Coronary Artery Disease: an Economical and Beneficial Investigative Algorithm
Myocardial infarction with nonobstructive coronary arteries (MINOCA) is a puzzling clinical entity, coupled with potential multiple pathophysiological mechanisms, often makes disease classification, investigation and management difficult. Despite presence of myocardial damage and increased risk for the future, many patients are discharged undiagnosed, thus the specific cause is not effectively treated.
GMP-Compliant Production of a Fluorescent Antibody for in vivo Molecular Endoscopy in a Phase I/IIa Clinical Study in Inflammatory Bowel Disease Patients
Therapeutic response to anti-TNF antibody treatment in inflammatory bowel diseases is strongly influenced by transmembrane tumor necrosis factor (mTNF) expression in the intestinal mucosa. Fluorescent anti-TNF antibodies applied for in vivo molecular endoscopy have shown to be able to quantify mucosal mTNF expression in real-time and predict response to subsequent anti-TNF treatment in individual patients with Crohn’s.
Effectiveness of a Community-based Cardiopulmonary Rehabilitation Program to the Elderly Recovered from Coronavirus Disease 2019 (COVID-19
Coronavirus Disease 2019 (COVID-19) is an infectious disease that affects patients’ lung function and thus exercise tolerance. Elderly patients have shown to have more severe and long-term symptoms after contracting COVID-19. Limited evidence has been published on the effectiveness of cardiopulmonary rehabilitation programme for elderly patients recovered from COVID-19. Therefore, the aim of this study was to launch and evaluate the effectiveness of a communitybased cardiopulmonary rehabilitation programme.
Isolated Temporal Bone’s Paget Disease: A Case Report
Paget’s bone disease (PBD) is a benign tumor of osteoclasts. We report a case of an isolated temporal bone’s Paget disease with unusual evolution to a rapidly functional degradation of vestibulocochlear system. A 60 years old female was
admitted for an isolated, left sided mastoid tumefaction without any inflammatory signs. Initial temporal bone computed tomography (CT) showed a left cotton wool appearance without any ossicles lesion or vestibulocochlear extension.
Anatomo pathological tests confirmed the diagnosis. The outcome was marked by the occurrence of vestibulocochlear
symptoms. Treatment had consisted on subtotal surgery in combination with oral bisphosphonate with improvement of
her clinical conditions. The post operative’s follow-up was simple without any abnormalities. PBD of temporal bone is a
benign disorder. Imaging is considered the most useful diagnosis modality for revealing the disorder that will be confirmed by histological tests. The treatment is based on medical approaches and surgery has few indications.
Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath
The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
Editorial Board Members Related to disease
Kuldip S. Sidhu
Associate Professor
Faculty of Medicine
University of New South Wales
Australia
Faculty of Medicine
University of New South Wales
Australia
Majeda Al-Farajat
Director
Quality and Patient Safety
Prince Sultan Cardiac Center
Saudi Arabia
Quality and Patient Safety
Prince Sultan Cardiac Center
Saudi Arabia
Fernando A. Herrera
Assistant Professor
Department of Surgery
Medical University of South Carolina
United States
Department of Surgery
Medical University of South Carolina
United States
VANA SPOULOU
Associate Professor
Department of Paediatrics
University of Athens Medical School
Greece
Department of Paediatrics
University of Athens Medical School
Greece
Insop Shim
Professor
Department of Medical Science
College of Korean Medicine
Kyung Hee University
South Korea
Department of Medical Science
College of Korean Medicine
Kyung Hee University
South Korea
Luis Ulloa
Associate Professor
Department of Surgery
Rutgers New Jersey Medical School
United States
Department of Surgery
Rutgers New Jersey Medical School
United States
Andrey Budanov
Assistant Professor
Department of Human and Molecular Genetics
Massey Cancer Center
United States
Department of Human and Molecular Genetics
Massey Cancer Center
United States
Chunying Li
Assistant Professor
Department of Biochemistry and Molecular Biology
Wayne State University School of Medicine
United States
Department of Biochemistry and Molecular Biology
Wayne State University School of Medicine
United States
Songon An
Assistant Professor
Department of Chemistry and Biochemistry
University of Maryland Baltimore County
United States
Department of Chemistry and Biochemistry
University of Maryland Baltimore County
United States
Vladimir W. Spolsky
Associate Professor
Division of Public Health & Community Dentistry
School of Dentistry
University of California
United States
Division of Public Health & Community Dentistry
School of Dentistry
University of California
United States