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Articles Related to disease

Treatment of Erdheim-Chester Disease with High Dose Pegylated IFN-α: a Case Report and Literature Review

Erdhein-chester disease is a rare non-Langerhans histocytes that can involve multiple systems, with bone involvement as the most common. We reports a 39-year-old female who visited the hospital due to pain in both lower limbs, combined with clinical manifestations, imaging, and laboratory tests, Erdhein-Chester disease was prelimi narily diagnosed. The diagnosis was confirmed by the presence of BRAF V600E mutation and tissue cells on biopsy of the right tibia. We discussed the disease based on literature review, aiming to improve the understanding of clinicians.
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Hemoglobin SC Disease with COVID-19 Presenting with Multiple Infarcts and Acute Splenic Sequestration Crises

Hb SC disease is a type of hemoglobinopathy that can be viewed as a hybrid of hemoglobin S and C. In this disorder there is co-inheritance of one Hbs gene and one HbC gene resulting in a milder phenotype than sickle cell anemia (SCA). Whereas SCA clinical features have been extensively studied, very few studies have been dedicated specifically to HbSC disease as most cases are reported to be silent or of mild severity. As the pandemic continues to evolve with the novel Sars-CoV-2 virus we have learned it can lead to thrombotic complications which could be fatal if not detected early. Of those requiring admission to the intensive care unit, most carry multiple comorbidities (hypertension, diabetes mellitus etc.) leading to worse clinical outcomes. Here, we present a case of a young adult patient with silent hemoglobin SC disease who tested positive for SARS-CoV-2 leading to multiple infarcts, splenic sequestration and respiratory failure. The concurrence of a hemoglobinopathy and COVID-19 should warrant heightened clinical suspicion for unusual outcomes. Hence, providers must remain vigilant while treating any patient with any hemoglobinopathy in the setting of COVID-19.
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Spine Osteonecrosis Related to Sickle Cell Disease

Analyze the clinical profile of the spine with osteonecrosis in sickle cell disease. 610 patients were followed-up in this study between 2000 and 2017. 98 osteonecrosis were identified, 48 in the lumbar spine, 40 in the thoracic spine and 10 in both spine segments. We analyzed sex, age, genotype, and pain. Magnetic resonances and radiographs of the spine were performed.
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Association between Chronic Obstructive Pulmonary Disease Severity and Platelet Values

To investigate the association between platelet values and COPD severity using linear variables in order to better explain and explore these correlations.
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Ethnobotanical Knowledge of Rabbit Breeder’s Community for Treating Livestock Diseases in Benin

The study aims to inventory the medicinal plants used in feeding, health and reproduction of rabbits. The surveys were carried out at 248 rabbit’s breeders in southern Benin. The identification of frequent species has been carried out. The ethnobotanical data were analyzed using various quantitative indices calculated for each of the medicinal plants recorded such as relative frequency of citations (RFC), informant consensus factor (ICF), relative importance index (RII), use value (UV), family importance value index (FIV), and level of fidelity (FL).
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Adolescent Idiopathic Scoliosis Progression and Quality of Life. Correlation between SSS-IoT Risk Scale Score and the Main Factors Determining the Disease Potential Progression

It has been identified several factors that can determine the severity and progression of adolescent idiopathic scoliosis (AIS). The natural evolution of this disease has been extensively studied in different populations. However, no practical tool encompasses the main factors determining this disease’s potential progression.
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Can Vitamin D Deficiency be a Risk Factor for Coronary Artery Disease? A Large Cross-Sectional Study of Patients Referred to Cardiovascular Clinic

Cardiovascular disease (CVD) is one of the most common causes of mortality and morbidity worldwide.Coronary artery disease (CAD) is the most common form of CVD. To prevent CAD we need to assess the risk of future CAD in all patients referred for cardiovascular care, but each of the several available systems for risk assessment has its own limitations. This study was designed to determine whether vitamin D deficiency is a potential risk factor for CAD.
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ABHD6 Inhibition Rescues a Sex-Dependent Deficit in Motor Coordination in The HdhQ200/200 Mouse Model of Huntington’s Disease

Huntington’s Disease is associated with motor behavior deficits that are lessened by few therapeutic options. This preliminary study tested if pharmacological inhibition of α/β-hydrolase domain containing 6 (ABHD6), a multifunctional enzyme expressed in the striatum, rescues behavioral deficits in HdhQ200/200 mice.
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Unexpected Improvement of Chronic Neurological Disease after Recovery from COVID-19 Infection in Four Patients

During the COVID-19 pandemic, physicians actively searched for adverse neurological complications or coagulopathyrelated strokes, but no protective effects were yet reported. We hereby describe our observations at a Geriatrics / Neurology facility on a range of neurological disorders encountered among COVID-19 patients followed for disabling neurological disease (degenerative or post traumatic dementia). We observed a very significant clinical improvement in 4 patients aged 43 to 78, who were in nursing skills home or at home and followed up for a disabling neurological disease for 2 to 5 years. They were affected by COVID-19 between March and October 2020.
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Association between Helicobacter pylori Infection and Early Kidney Damage in a Healthy Population

This retrospective study was conducted at the Physical Examination Center of the First Hospital of Jilin University, China. The 5594 healthy individuals were included based on strict predefined inclusion and exclusion criteria from 8821 participants who received health examinations between January 2019 and April 2019. H. pylori infection was detected using a commercial carbon-14 urea breath test. Logistic regression analysis was used to determine the relationships of biomarkers of early kidney dysfunction with H. pylori infection, after adjusting for age, sex, and metabolic factors.
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Plasma Exchange for Neuroborreliosis Associated with Guillain Barre Syndrome

Lyme neuroborreliosis (LNB) is a rare infectious disorder of the nervous system caused by Borrelia burgdorferi spirochetes. Different neurological conditions were reported in the disease.
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Cerebral Venous Thrombosis in Behcets Disease about 24 Patients

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Kidney Injury in Ordinary Adult Cases of Coronavirus Disease 2019

Kidney injury has been observed broadly in severe and critical coronavirus disease 2019 (COVID-19) patients, but the impairment of renal function in ordinary cases has rarely reported. We conducted this study to explore whether patients in ordinary condition suffered from kidney injury during the course of COVID-19 and to find out a proper indicator for detecting kidney injury in COVID-19 patients.
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Factors Affecting Exercise Self-efficacy in Predialysis Chronic Kidney Disease Patients

There was significant evidence to suggest that exercise improves physical function, symptom burden, and quality of life in predialysis chronic kidney disease (CKD) patients. However, most CKD patients cannot adherence to minimum recommended levels of exercise.
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Conventional and Advanced Nanotechnological Approaches for Wastewater Treatment

The industrialization, urbanization and economic growth have placed a much higher demand of clean water and energy worldwide. The human activities have constantly been contaminating the reservoirs of fresh water which as a result, has triggered a global challenge to keep up the demand and supply of the fresh water for an optimal human survival. Wastewater effluents generated through commercial and industrial activities have been released to the freshwater resources either directly or indirectly
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Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath

The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
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Editorial Board Members Related to disease

Zhuoxiao Cao

Scientist
Cell biology department
Novo Nordisk China R&D
China

Ercument Genc

Professor
Department of Fisheries and Aquaculture Engineering
Faculty of Agriculture
Ankara University
Turkey

Lan-Juan (Jean) Zhao

Assistant Professor
Department of Biostatistics and Bioinformatics
Tulane University
United States

Joseph Alpert

Professor
Department of Medicine
University of Arizona
United States

Massimo Caputo

Professor
Congenital Cardiac Surgery
Bristol Heart Institute
United Kingdom

Frank F. Seghatol

Assistant Professor
Division of Cardiology
University of Alabama
United States

Rukman Awang Hamat

Associate professor
Department of Medical Microbiology and Parasitology
Universiti Putra Malaysia
Malaysia

Frank C. Barone

Professor
Department of Neurology
SUNY Downstate Medical Center
United States

Xiaoming Yang

Professor
Department of Radiology
University of Washington School of Medicine
United States

SCOT MICHAEL LEWEY

Medical Director
Adult Gastroenterology Program
Castle Rock Adventist Hospital
United States
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