Articles Related to dopamine

Artificial light at night has been reported to have significant effects on the physiology and behaviour of animals by its impact on their circadian rhythm. This study investigated the effect of artificial light spectra at night on neurotransmitter activities and neurobehavioural changes in the albino rat. Blue (470 nm) and red (665 nm) lights were used; with ambient light and darkness serving as positive and negative controls, respectively. The rats were exposed to daylight from 6 am to 6 pm and 12 hours of artificial light (6 pm - 6 am) daily (light sources were 13 Watt compact florescent electric bulbs). Neurobehavioural outcomes were measured using the Open Field Test (OFT) and Morris Water Maze (MWM).

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Methamphetamine is one of the most commonly abused illegal stimulants and causes the release of dopamine, norepinephrine and serotonin. These neurotransmitters trigger vasospasm, causing persistent tachycardia, hypertension, and direct myocardial toxicity. Moderate usage of methamphetamine can increase cardiac output and myocardial contractility. However, larger doses can cause depression of the myocardium.

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The recent resurgence of interest in m6A has been spurred by some intriguing findings detailing the effects and dynamics of this epigenetic modification. The m6A modification is a highly reactive and fluid modification which can respond rapidly to a broad variety of stimuli, and translate these signals into cellular activity. The little information that has been established on its functional capacity has opened up many new avenues of research and has tremendous implications for several fields of study.

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