Articles Related to drosophila

Background to Study: Lead (Pb) is ubiquitous in the environment and toxic. It has many negative effects on many organs and induces biochemical, physiological, and behavioural alterations on the brain. Monodora myristica is a calabash nutmeg belonging to the family of Annonaceae.It is a rich source of flavonoids which have been shown to exhibit both antioxi-dant and anti-inflammatory properties. We evaluated the protective role of Monodora myristica on lead-induced toxicity in D. melanogaster in this study

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Mutation in a single nucleotide of a gene has the potential to change the structure and/or function of its protein. Albeit simply saying, it is not observed to be a general phenomenon. The effect of mutation is primarily determined by the stereochemical nature of the amino acid which has replaced the previous amino acid, resulting in the residue location being affected. Here we show that despite a change in the frequency of occurrence of a particular amino acid in a particular protein in different types of organisms, the overall function of the protein can still remain unaffected, even when the resultant protein conformation is relatively altered.

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The amyloid precursor protein (APP) is mainly known for being the precursor of the ß-amyloid peptide, which accumulates in plaques found in the brain of Alzheimer’s disease patients. Expression in different tissues and the degree of sequence identity among mammals indicate an essential and non-tissue specific physiological function.

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