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Articles Related to drosophila

Functional Protein Domains Evolve Very Specifically Over Mutations

Mutation in a single nucleotide of a gene has the potential to change the structure and/or function of its protein. Albeit simply saying, it is not observed to be a general phenomenon. The effect of mutation is primarily determined by the stereochemical nature of the amino acid which has replaced the previous amino acid, resulting in the residue location being affected. Here we show that despite a change in the frequency of occurrence of a particular amino acid in a particular protein in different types of organisms, the overall function of the protein can still remain unaffected, even when the resultant protein conformation is relatively altered.
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Amyloid beta precursor protein: forgotten facts of the most studied protein in the 21st Century*

The amyloid precursor protein (APP) is mainly known for being the precursor of the ß-amyloid peptide, which accumulates in plaques found in the brain of Alzheimer’s disease patients. Expression in different tissues and the degree of sequence identity among mammals indicate an essential and non-tissue specific physiological function.
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Editorial Board Members Related to drosophila

AMY H. TANG

Associate Professor
Department of Microbiology and Molecular Cell Biology
Eastern Virginia Medical School
United States

SAN MING WANG

Associate Professor
Department of Genomics
University of Nebraska Medical Center
United States
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