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Articles Related to drugs

Fatal road accidents in Spain: psychoactive substances in killed drivers in 2014

Road traffic accidents (RTAs) are often related to impairment by alcohol or drugs. The objectives of this study is to present toxicological data on drivers killed in traffic accidents in Spain in 2014 from a sample of 614 drivers and 240 (out of 614) with positive results for alcohol, illicit drugs and psychoactive medicinal drugs.
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An Introduction to the Approaches of Novel Drug Delivery Systems for Acquired Immune Deficiency Syndrome (AIDS)

The currently available anti HIV agents have several drawbacks such as short half life, low bioavailability, poor CNS penetration and retention, hepatic first pass metabolism, undesirable side effects and frequent dosing regimen.
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The Ongoing Battle for Syringe Exchange

Syringe exchange programs (SEPs) have been shown to be effective in reduction of infectious disease rates in several studies over the years.
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Nutritional and Biological Control Synergism against Gastrointestinal Nematodes in Small Ruminants

Parasitic gastroenteritis caused by gastrointestinal nematodes (GIN) continues to be a major constraint against profitable small ruminant production. The increasing prevalence and severity of anthelmintic-resistant nematodes in many parts of the world has led to a search for non-chemical control options.
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Effects of Oxytocin and Carbetocin on Haemostatic Variables in Pregnant Women after Cesarean Section

Uterine atony is the first cause of haemorrhage at delivery. To prevent post partum major bleeding uterotonic prophylactic drugs are commonly used after caesarean section. Few studies showed an haemostatic activation after oxytocin infusion while no data are available on carbetocin.
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Canakinumab in the Treatment of Erosive Hand Osteoarthritis: A Case Series

Erosive hand Osteoarthritis (EOA) is a common and debilitating form of hand OA for which there are no proven or efficacious therapies. Interleukin-1 beta (IL-1β) plays a prominent role in OA joint inflammation. Canakinumab is a selective IL-1β inhibitor.
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Immunodeficiency and Microbial Infections

Immunodeficiency refers to failure of immune system to encounter infections by different microbial pathogens such as fungi, bacteria, viruses and protozoan. This is called acquired or secondary immunodeficiency syndrome (SIS).
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A New Bi-Functional Derivative of Polyethylene Glycol as Molecular Carrier for Eugenol and Ibuprofen

Eugenol (EU) and ibuprofene (IBU) were covalently bound to a bi-functionalized PEG, used as molecular carrier of drugs and the release kinetics of the two bioactive molecules was studied in vitro in buffer solution at pH 7.4, in simulated gastric fluid and in mouse plasma.
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Nanotechnology Approaches for Antiretroviral Drugs Delivery

The development of effective drug delivery approaches for the treatment of AIDS and HIV infection is a global challenge. The advent of multidrug, highly active antiretroviral therapy (HAART), have increased the life span of HIV-infected patients.
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Identification of Pyrrolidinophenone-type Designer Drugs by Gas Chromatography/ Time-of-Flight Mass Spectrometry

Use of gas chromatography (GC) combined with time-of –flight mass spectrometry (TOFMS) with soft ionization generated with three different plasma gases (i.e., Xe, Kr, Ar) was evaluated for the identification of several pyrrolidinophenone-type designer drugs that are commercially available.
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Nanotechnology Commercialization: Prospects in India

Nanotechnology manipulates and creates matter to formulate nanometer scale materials and objects. It is an interdisciplinary field that involves a wide range of scientific and engineering disciplines, and has societal implications.
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Extensive Worm Infestation: A Case Report

Ascariasis is the most common helminthic infection in the world and is seen mostly in the developing countries of Asia. We report a case of heavy worm infestation in a 2-year-old child who presented with worms in small bowel, common bile duct and liver with abscesses. He was managed conservatively and recovered well without any sequalae.
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Croscarmellose Sodium Efficiency in the Development of a Generic Capsule Formulation of Piroxicam, Comparable Dissolution Profile to the Innovator Product, Feldene

The objective of this study was to evaluate the encapsulation performance of Croscarmellose sodium, a superdisintegrant in a low-dose, poor-solubility drug formulation and the in-vitro dissolution performance of the Piroxicam capsules. Preparation, characterization and evaluation of the effects of the different concentrations of carmellose sodium and the amount of dried starch on in-vitro dissolution of Piroxicam capsules. Piroxicam was chosen for its very low solubility in biological fluids, which result in poor systemic bioavailability after oral administration. Piroxicam can be categorized as Class II drugs according to the Biopharmaceutics Classification System.
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Descriptive Study of Exposure to Inhalation Zanamivir and Pregnancy-Related Outcomes

The Health Improvement Network (THIN) provided data from UK General Practitioners (GPs) for 144 pregnant women who were prescribed zanamivir and 144 age- and date-matched untreated comparators with no recorded diagnosis of influenza. Groups were assessed for baseline characteristics, treatment-emergent diagnoses in the mother, pregnancy outcomes and congenital malformations diagnosed in the offspring within 28 days of birth.
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Sarcoidosis - A Case of “Resistant Tuberculosis”

Sarcoidosis is a multisystem granulomatous disease of unknown aetiology. It usually has a benign course, but those cases with multi system involvement have poorer prognosis. Sarcoidosis is an under diagnosed disease in India, probably due to the close resemblance to tuberculosis and the lack of awareness. But this disease is not so rare in India, as previously thought.
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Editorial Board Members Related to drugs

Martin Michaelis

Professor of Molecular Medicine
Centre for Molecular Processing and School of Biosciences
University of Kent
United Kingdom

Janet Liversidge

Professor
School of Medicine and Dentistry
University of Aberdeen Institute of Medical Sciences
United Kingdom

Bechan Sharma

Professor
Department of Biochemistry
University of Allahabad
India

Frank C. Barone

Professor
Department of Neurology
SUNY Downstate Medical Center
United States

ALAA EL-DEEN BAKRY YASSIN

Associate Professor
Department of Pharmaceutical Sciences
King Saud bin Abdulaziz University for Health Sciences
Saudi Arabia

Viorica Lopez-Avila

Research Scientist
Agilent Technologies
United States

Richard Lobo

Associate Professor
Department of Pharmacognosy
Manipal College of Pharmaceutical Sciences
India

JANAK PADIA

Associate Professor
Center of Biomolecular Therapeutics
University of Maryland
United States

Dell R. Burkey

Professor
Department of Anesthesiology and Critical Care
Hospital of the University of Pennsylvania
United States

R. SURESHKUMAR

Assistant professor
Department of Pharmaceutics
JSS College of Pharmacy
India
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