Articles Related to eNOS
Case Report: Pyoderma Gangrenosum in IBD Treated with Tofacitinib
Pyoderma gangrenosum is a rare ulcerating skin disease often presenting as an extra intestinal manifestation of IBD and is
difficult to manage. Treatment options for pyoderma gangrenosum include steroids, calcineurin inhibitors and anti TNF
agents. Here in, we report a case of recurrent Pyoderma gangrenosum with Ulcerative Colitis that was successfully managed
with Tofacintib, a JAK inhibitor
Iatrogenic Laryngotracheal Stenosis in Children: a Case Report
Laryngotracheal stenosis is one of the important causes of pediatric airway obstruction, and the etiology can be classified as
congenital and acquired. With the widespread use of tracheal intubation and tracheotomy in pediatric emergency, iatrogenic
laryngotracheal stenosis is gradually replacing trauma and infection as the major cause of acquired laryngotracheal stenosis [1].
Nowadays, open surgery is the first choice for severe laryngotracheal stenosis cases [1,2]. Here, we describe a case of childhood
iatrogenic severe laryngotracheal stenosis, and the reflection on the current treatment methods of children with laryngotracheal
stenosis.
A Rare Case: Pylor Stenosis with Anal Atresia and Vesicoureteral Reflux
In newborns, vomiting is a very frequent find. Especially in a newborn who has undergone major surgery,
postoperative vomiting is a common occurrence. In our study, we aimed to present a newborn who was operated on first
for anorectal malformation (ARM) and then for vesicoureteral reflux (VUR) and diagnosed with infantile hypertrophic
pyloric stenosis (IHPS) upon persistent vomiting
Novel Multi-Functional Dental Cement for Enamel Remineralization and AntiCariogenic Bacteria Activity
This experimental study evaluated the release of fluoride and several minerals related to remineralization from novel functional cement, apatite ionomer cement (AIC), and its anti-bacterial properties compared with glass ionomer cement (GIC) and surface pre-reacted glass-ionomer filler containing composite resin (giomer). Conventional GIC (Fuji III, GC Co., Tokyo, Japan) was used as the control and fundamental materials. In the AIC powder, 28% wt of GIC powder was replaced with spherical-shaped hydroxyapatite powder. The giomer, BeautiSealant (Shofu Co., Kyoto, Japan), was used as a positive control. Each specimen was immersed in deionized water and analyzed by inductively coupled plasma atomic emission spectrometry (for Al, Si, P, Ca and Sr) and a fluoride-selective electrode. Antibacterial activity against Streptococccus mutans was evaluated using the adenosine-5’-triphosphate luminescence method. Concentrations of released ions from AIC specimens were significantly higher than those from GIC and giomer specimens. Regarding antibacterial activity, luminescence intensity of the AIC group was significantly lower than that of the control and giomer groups. It was concluded that AIC could be a most suitable material for pit and fissure sealant for enamel remineralization and anti-cariogenic and -bacterial activity.
Splenic Injury after Screening Colonoscopy; Could that Happen Twice? An Unusual Case Report
Iatrogenic splenic injury is a known but rare complication of colonoscopic procedures. Our department describes a very interesting case of the same complication that occurred twice on the same patient. The patient had an elective colonoscopy for microcytic anemia and shortly after the endoscopic procedure she developed excessive abdominal pain and had a syncope episode. She gradually became hemodynamically unstable and needed proper resuscitation. An abdominal tomography scan performed which surprisingly demonstrated active intra-abdominal bleeding pointing a ruptured spleen as the source of the hemorrhage. This finding surprised us given the fact that her past surgical history included a previous splenectomy for the same complication 14 years ago.
Suspected Allergic Reaction in Bottlenose Dolphins (Tursiops truncatus)
Over the course of several years, three members of a Bottlenose dolphin (Tursiops truncatus) group showed periodical bouts of pruritus and dermatological lesions. The affected animals were a 25-year-old cow and her 5 and 7-year-old offspring, all housed in a mixed indoor/outdoor facility. The signs were first noted in 2005 and escalated over time until 2012, when a final diagnosis of the problem was attempted. Diagnostic tests included blood analysis and skin biopsies, swab microbiological cultures from the wheals, intradermal tests and response to treatment with corticosteroids. Clinical picture and histopathological findings, as well as response to methylprednisolone, were considered compatible with an allergic dermatitis.
Serum Phosphate - A Need to Revise Clinical Guidelines?
This paper does not present new experimental data. It is based on existing literature and 40 years of clinical experience as an anesthesiologist. Author believes that it is necessary to look into clinical guidelines for some common, but serious medical conditions
Review on Pharmacological Activities of the Peptides from Scorpion Buthus Martensii Karsch
In China, the scorpion Buthus martensii Karsch is used as functional food and medicinal materials. The scorpion, scorpion venoms and their extracts are effective in treating a variety of nervous system diseases such as epilepsy, apoplexy pains and facial paralysis.
Gastric Cancer in Young Patients Under The Age of 30 Years
A retrospective analysis was conducted on 8466 gastric cancer patients from different age groups treated in Minsk City Clinical Oncological Hospital from 1998 to 2013. Of these, 72 (0.85%) patients were under the age of 30, 72.2% of which were diagnosed with clinical stage IV cancer
m6a RNA Methylation: The Implications for Health and Disease
The recent resurgence of interest in m6A has been spurred by some intriguing findings detailing the effects and dynamics of this epigenetic modification. The m6A modification is a highly reactive and fluid modification which can respond rapidly to a broad variety of stimuli, and translate these signals into cellular activity. The little information that has been established on its functional capacity has opened up many new avenues of research and has tremendous implications for several fields of study.
Development of Severe Hypophosphatemia from Acquired Fanconi Syndrome during Treatment with Abiraterone
The first patient was a 77 year old man who had been on abiraterone for 12 months before his phosphorous was checked. At that point, it was 0.6 mg/dl, which is severely decreased. A full work up for hypophosphatemia showed normal parathyroid hormone and 25-hydroxyvitamin D. A urine study showed inappropriate excretion of phosphorous along with aminoaciduria and normoglycemic glucosuria.
Extensive Worm Infestation: A Case Report
Ascariasis is the most common helminthic infection in the world and is seen mostly in the developing countries of Asia. We report a case of heavy worm infestation in a 2-year-old child who presented with worms in small bowel, common bile duct and liver with abscesses. He was managed conservatively and recovered well without any sequalae.
MAPK Pathway in Skeletal Muscle Diseases
Mitogen-Activated Protein Kinase (MAPK) pathway is a signal transduction pathway that functions in a wide range of physiological and pathophysiological cellular events including cell proliferation, differentiation, apoptosis, migration, inflammation, metabolic disorders and diseases.
Editorial Board Members Related to eNOS
Dilip K. Tosh
Laboratory of Bioorganic Chemistry
National Institute of Diabetes and Digestive and Kidney Diseases
National Institutes of Health
USA
National Institute of Diabetes and Digestive and Kidney Diseases
National Institutes of Health
USA
LAURA IRIS COSEN-BINKER
Assistant Professor
Department of Molecular and Cell Biology
Boston University
USA
Department of Molecular and Cell Biology
Boston University
USA
Joseph Alpert
Professor
Department of Medicine
University of Arizona
United States
Department of Medicine
University of Arizona
United States
Marco Berlucchi
Department of Pediatric Otorhinolaryngology
Spedali Civili
Italy
Spedali Civili
Italy
Weibin Shi
Associate Professor
Department of Radiology & Medical Imaging
University of Virginia
United States
Department of Radiology & Medical Imaging
University of Virginia
United States
Carla Cicala
Professor
Department of Pharmacy
University of Naples Federico II
Italy
Department of Pharmacy
University of Naples Federico II
Italy
Bulang Gao
Professor
Department of Medical Research
Hebei Medical University
China
Department of Medical Research
Hebei Medical University
China
Adolfo Godoy Pinto
Professor
Veterinary Medicine and Animal Science
University of Chile
Chile
Veterinary Medicine and Animal Science
University of Chile
Chile
Alcides Troncoso
Professor
Department of Microbiology and Infectious Diseases
University of Buenos Aires
Argentina
Department of Microbiology and Infectious Diseases
University of Buenos Aires
Argentina
Alcides Troncoso
Professor
Department of Microbiology and Infectious Diseases
University of Buenos Aires
Argentina
Department of Microbiology and Infectious Diseases
University of Buenos Aires
Argentina