Articles Related to formulation
Formulation and Evaluation of Clindamycin Peel-Off Gel Face Mask against Acne Vulgaris
The main aim of this project is to formulate and evaluate Clindamycin peel-off gel face mask against Acne vulgaris. Peel off
gel mask of Clindamycin phosphate was formulated using different excipients like Triethanolamine, Carbopol, Polyvinyl Alcohol, Glycerine, Xanthan gum, and Benzyl alcohol. Formulation of different composition of polymer was formulated and
their pH, extrudability, homogeneity, spreadability, viscosity, washability and other parameters like drug content, permeability and drug release were evaluated. The result showed that the concentration of PVA and Carbopol which are the main polymers used in the formulations had effect on the drug content, drug release, permeability, spreadability and other parameters. The peel off mask prepared by using different concentration of these two polymers showed satisfactory result in all the
evaluated parameters.
Bioequivalence Studies of Two Formulations of Rivaroxaban 10 Mg Coated Tablets under Fasting Conditions and 20 Mg Coated Tablets Under Fed and Fast Conditions And its Pharmacokinetic Comparison In Healthy Subjects
Justificative: This trial was conducted in order to register a new generic product of Rivaroxaban.
Objective: To evaluate the bioequivalence of rivaroxaban formulations manufactured by Eurofarma Laboratórios S/A and
the reference drug, Xarelto (Bayer) under fasting and fed conditions.
Methods: Three randomized, open label, balanced, 2 treatments, 4 periods, 2 sequences, single dose, full replicate, crossover
studies in 48 healthy adult human subjects under fed and fasting conditions for rivaroxaban 10 mg and 20 mg. Rivaroxaban
concentrations in plasma were determined using a validated HPLC-MS/MS method.
A Bioequivalence Study of Two Formulations of Lacosamide
This study was conducted to compare the bioavailability of two tablet formulations containing 200 mg Lacosamide (one Lacosamide 200 mg film-coated tablet marketed in Italy as Ollat®, one Vimpat® coated tablet). 20 healthy subjects were enrolled in a single-center, randomized, single-dose, laboratory-blinded, 2-period, 2-sequence, crossover study, with a minimum washout period of 7 days. All the 20 subjects completed the study. Plasma samples were collected up to 72.0 hours post-dosing. Lacosamide levels were determined using a validated high-performance liquid chromatography
with tandem mass spectrometry (HPLC/MS/MS) method
Bioequivalence Study of Two 80 Mg Valsartan Tablets Formulations in Healthy Chinese Subjects Under Fasting and Fed Condition
Objective: The purpose of this study was to compare the bioavalability between the two 80 mg Valsartan Tablets formulations and to evaluate the bioequivalence of Reference and Test formulations of Valsartan Tablets 80 mg in Healthy adult chinese Male and Female subjects under Fasting and Fed condition.
Formulation and In-vitro Characterization of Fluoxetine Hydrochloride Loaded Fast Dissolving Oral Film Using HPMC 15CPS and HPMC K4M
Fluoxetine Hydrochloride (FH), a selective serotonin reuptake inhibitor (SSRI) is a drug of choice in depression, obsessive-compulsive disorder (OCD), bulimia nervosa, etc. Though tablet, capsules, oral solution, or syrup are currently available conventional dosage form of FH, modified or immediate-release formulations for fast onset of action is of utmost importance.
Comparative Bioequivalence Studies of Pantoprazole 40 mg Delayed-Release Tablet Formulations in Healthy Thai Volunteers
Pantoprazole is a H+,K+-ATPase enzyme inhibitor for the treatment of acid-related gastrointestinal diseases. The Government Pharmaceutical Organization (GPO), Thailand had developed Pantoprazole GPO® (pantoprazole 40 mg delayed-release tablets) as a generic substitute for the corresponding innovator product, CONTROLOC® 40 mg.
Formulation and Characterization of Diclofenac Potassium Transdermal Patches Prepared with Ficus auriculata Fruit Mucilage and Hydroxypropyl Methyl Cellulose K4M
The delivery of the drug at a predetermined controlled rate and its systemic effect is utmost important. Topically
administered medicaments in the form of patches is being popular for its effectiveness. The main objective of this research was to
formulate matrix-moderated transdermal patch of diclofenac potassium and to evaluate them concerning various in-vitro parameters.
Formulation and Evaluation of Sustained Occular Delivery of Ciprofloxacin Hydrochloride
The aim of the present work was formulation and evaluation of in-situ gelling system of Ciprofloxacin Hydrochloride. The poor
bioavailability and therapeutic response exhibited by conventional ophthalmic solution due to rapid precorneal elimination of the drug
may be overcomed by the use of in-situ gel forming system that are installed as drop into the eye and undergo sol to gel transition in the
cul-de-sac.
Pharmacokinetics Bridging Study of a 400 Mg Extended Release Formulation of the Novel Fumaric Acid Ester PPC-06 (Tepilamide Fumarate) in Healthy Male Volunteers
Tepilamide fumarate (PPC-06) is a new, patented prodrug of monomethyl fumarate (MMF), belonging to the fumaric acid esters
(FAEs) class of drugs. The efficacy and safety of a 400 mg PPC-06 dose administered twice daily, achieved thus far through concomitant
intake of two tablets of 200 mg, was demonstrated previously in two Phase 2 clinical trials on patients with moderate to severe chronic
plaque-type psoriasis.
Bioequivalence Evaluation of Two Clopidogrel Immediate Release Tablet Formulations in Healthy Thai Volunteers Under Fasting Conditions
Clopidogrel is used for acute coronary syndrome and prevention of atherothrombotic events. To improve clinical outcomes, patient
adherence to treatment is necessary. However, continuous use of branded product may cause economic burden to patients and
healthcare system. The Government Pharmaceutical Organization (GPO), Thailand had developed a generic product of clopidogrel to
reduce cost of treatment and improve accessibility to medicines for Thai people.
Cognitive Enhancers Derived from Edible Crops
The concept of an effective cognitive boosting nootropic supplement is gaining traction with consumers, neuroscientists and regulators
alike and it is therefore unsurprising that scientifically validated Nootropics are highly prized. New research demonstrates edible crops
could be useful sources to mine for new nootropics; plant extracts enriched with an array of cognitive enhancing metabolites. There is merit
in investigating these plant species. Metadata has identifies consuming specific fruit and vegetables positively affects cognitive function;
therefore these same edible crop plants present as opportunities for developing nootropic formulations. This hypothesis is supported
by positive data obtained through clinical testing [e.g. extracts of tomato (Solanum lycopersicum), herbs from the Genus Salvia, cocoa
(Theobroma), tea (Camellia sinensisor) and coffee (Coffea Arabica). This review will discuss clinically tested cognitive enhancers derived
from edible crop species and discuss their use alongside other classes of nootropics.
Impact of the Biofield Energy Healing Based Test Formulation on Various Health Biomarkers Using Cell-Based Assays
Various complementary approaches have been used against multiple organ dysfunction syndrome (MODS), which is the major
contributor in high mortality among the healthcare centers.
Evaluation of Anti-aging Effect of the Novel Test Formulation in Cell-based Studies using Β-Galactosidase Activity, Collagen Levels, and Protection against Oxidative Stress
The study was aimed to evaluate the antioxidant and antiaging potential of Biofield Energy Healing Treatment (the Trivedi Effect®)
on a novel test formulation in in vitro. The test formulation was divided into two parts
Bioequivalence Study of Olanzapine 5 mg Orally Disintegrating Tablet Formulations in Healthy Thai Volunteers under Fasting Conditions
A comparative randomized, single dose, two-way crossover, open label study was carried out to assess bioequivalence and tolerability of test (ZOLAN GPO®) and reference (Zyprexa Zydis®) products of olanzapine 5 mg orally disintegrating tablets for interchange ability in the same quality and safety.
Editorial Board Members Related to formulation
Matthew Tan
Associate Professor (ADJ)
Centre for Sustainable Tropical Fisheries and Aquaculture
James Cook University
Australia
Centre for Sustainable Tropical Fisheries and Aquaculture
James Cook University
Australia
V. Sankar
Professor & Head
Department of Pharmacy Practice
PSG College of Pharmacy
India
Department of Pharmacy Practice
PSG College of Pharmacy
India
Pasquale Russo
Department of Science of Agriculture
Food and Environment
University of Foggia
Italy
Food and Environment
University of Foggia
Italy
ABDUL AHAD
Assistant Professor
Department of Pharmaceutics
King Saud University
Saudi Arabia
Department of Pharmaceutics
King Saud University
Saudi Arabia
Scott Asbill
Professor of Pharmaceutics
College of Pharmacy & Health Sciences
Campbell University
United States
College of Pharmacy & Health Sciences
Campbell University
United States
Hamidah Ibrahim
Professor
Faculty of Computer Science and Information Technology
Universiti Putra Malaysia
Malaysia
Faculty of Computer Science and Information Technology
Universiti Putra Malaysia
Malaysia
ALAA EL-DEEN BAKRY YASSIN
Associate Professor
Department of Pharmaceutical Sciences
King Saud bin Abdulaziz University for Health Sciences
Saudi Arabia
Department of Pharmaceutical Sciences
King Saud bin Abdulaziz University for Health Sciences
Saudi Arabia
Rula M. Darwish
Professor
Department of Pharmaceutical Microbiology
University of Jordan
Jordan
Department of Pharmaceutical Microbiology
University of Jordan
Jordan
Richard Lobo
Associate Professor
Department of Pharmacognosy
Manipal College of Pharmaceutical Sciences
India
Department of Pharmacognosy
Manipal College of Pharmaceutical Sciences
India
Henry H. Y. Tong
Professor
School of Health Sciences
Macao Polytechnic Institute
Macau
School of Health Sciences
Macao Polytechnic Institute
Macau