Articles Related to immunoglobulin
Recurrent Ophthalmic Eczema Herpeticum with Hyper Immunoglobulin E Syndrome in A 4 Years-Old Boy
Eczema herpeticum (EH) is a skin infection caused by the herpes simplex virus (HSV) that occurs in individuals with atopic
dermatitis. It is characterized by the sudden appearance of vesicles and erosions with crusts over areas affected by eczema.
EH can range from mild and self-limiting in healthy adults to life-threatening in children, infants, and immunocompromised patients. Early treatment with antiviral therapy is crucial in preventing complications and mortality. EH is primarily
caused by a superinfection of HSV, usually HSV-1, in individuals with atopic dermatitis. Reactivation of HSV is more common than primary infection. Patients with atopic dermatitis are more susceptible to skin infections due to impaired skin barrier function and immune dysregulation. Disseminated cutaneous HSV infection can also occur in individuals with other
forms of dermatitis, known as Kaposi varicelliform eruption (KVE)
Treating Refractory Myasthenia Gravis with Rituximab – Case Report
Myasthenia gravis is an autoimmune disease characterized by motor plaque dysfunction due to antibodies against post-synaptic membrane proteins. Myasthenic symptoms classically wax and wane and are more intense at the end of the day, although they may be constant in severe pictures. Almost every patient have eyelid ptosis and double vision, and the majority of them also have proximal muscle weakness. Reversible cholinesterase inhibitors are the first-line treatment, but patients who do not achieve symptom control should receive immunosuppressive therapy, whose options include azathioprine, cyclosporine, mycophenolate, intravenous immunoglobulin and thymectomy, with different profiles of efficacy, safety and tolerability.
Kawasaki Disease Presented with Meningitis in an Egyptian Adolescent
An Egyptian male adolescent 12 years old presented with fever, loss of appetite, nausea and vomiting for 3 days. He had convulsion on admission. Physical examination revealed positive meningeal signs.
Anti-GnRH Receptor Monoclonal Antibodies, First-In-Class GnRH Analog
A monoclonal antibody (Mab) designated as GHR106 was generated against the extracellular domain (N1-29 synthetic peptide) of human gonadotropin releasing hormone (GnRH) receptor. It is a first-in-class GnRH analog and can serve as a drug candidate for potential applications in the treatment of human cancers and/or fertility regulations.
