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Evaluation of The Immunomodulatory In Vivo Activity of Laminaria Hyperborea Fucoidan Relative to Commercial (1,3/1,6)-Β-D-Glucans from Yeast and Mushrooms

A fucoidan with high ester sulfate content (38-40% by weight) has been isolated in a commercial scale process from Laminaria hyperborea harvested from the western coast of Norway. This is the first characterization of a fucoidan from this species of macroalgae. Ultra purified samples with negligible endotoxin levels were evaluated for cytokine expression in cultured human mononuclear cells.
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