Articles Related to lymphoma
Intravascular Large B-Cell Lymphoma, an Updated Review
Intravascular large B-cell lymphoma (IVBCL) is a rare but aggressive form of non-Hodgkin lymphoma. It is characterized by the malignant proliferation of lymphocytic tumor cells in the lumens of capillaries, small arterioles, and post-capillary venules. There exists two clinical variants: the Asian variant and the Western variant. The former is associated with neurologic and dermatologic signs and symptoms, whereas the latter often presents with splenomegaly, jaundice, and hemophagocytes. Lymphadenopathy is uncommon, and patients typically have nonspecific symptom
Profile of Adult Lymphomas in Sub-Saharan Africa: A Monocentric Study of Histoimmunochemical Aspects
A total of 26 NHL patients (56.5%) and 20 LH cases (43.5%), aged 32-11 and 51-18 years respectively, were selected. Polyadenopathy was noted in 95% of cases of HL and 73.1% of cases of NHL (p=0.002). Patients were at Ann Arbor Stage II-IV in 80% of cases for the NHL and 70% of cases for LH (p: 0 ,317). Type B-Cell NHL entities were Diffuse Large Cell B Lymphoma (34.6%), Follicular Lymphoma (15.4%), Mantle Lymphoma (7.7%), Lymphocytic Lymphoma (7.7%), and Malt Lymphoma (3.8%). The NHL was type T-Cell in 30.8% of cases including 19.2% of anaplastic lymphoma. The HL were classic (80%) and nodular lymphocyte predominant Hodgkin lymphoma (20%). Specific treatment was performed in 82.6% of cases, 28.9% of which were immunochemotherapy. Remission was noted in 52.4% of NHL patients and 70.3% of those with HL.
Small Cell Variant of Anaplastic Large Cell Lymphoma Presenting As Leukaemia: A Case Report and Review of Literature
Anaplastic large cell lymphoma with a small cell pattern is a rare T-cell lymphoma. This condition is frequently seen in young patients and should be considered in patients presenting with leucocytosis and constitutional symptoms. We report a case of small cell variant (SCV) of ALCL in a 68 year old man diagnosed by ALK immunohistochemistry (IHC) and cytogenetic analysis. The limitations of using only morphology in diagnosing this rare variant, has also been emphasised.
Tomotherapy Treatment of Chronic Lymphocytic Leukemia and Ocular Lymphoma
A sixty-five-years-old male patient with history of non-Hodgkin’s lymphoma of the right orbit and a fifty-years-old female patient with chronic lymphocytic leukemia with peripheral lymphocytosis were treated on TomoTherapy. In the first case, a 1 cm beam was used for planning a delivery of 30.6 Gy in 17 fractions with a sequential boost of 9 Gy in 5 fractions. Tumor involvement of the ipsilateral lens and lacrimal gland in the planning target volume necessitated a compromise between preserving patient’s vision and delivery of tumoricidal dose to the target. In the second case, 30 Gy in 20 fractions delivery was planned with a 2.5 cm beam. The tumor extended anteriorly and this technique allowed sparing more orbital tissue and required a high modulation factor.
Lymphoma Complicating IBD Immunomodulator Therapy: A Reminder to be Vigilant
Patients with Inflammatory Bowel Disease (IBD) not responding to steroid treatment should be considered for immunomodulator therapy. The risk of lymphoma in IBD patients treated with immunomodulators is a well-documented but rare complication and remains a subject of controversy. Here, we present two patients treated successfully in outpatient clinics on thiopurine immunomodulators who were admitted within weeks of each other with a diagnosis of lymphoma.
Challenges in the Pharmacological Management of Non Hodgkin’s Lymphoma in Children in the Maintenance Phase of Therapy at Kenyatta National Hospital
Non Hodgkin’s lymphoma is an extremely chemo sensitive with a five year event free survival of greater than 90% in developed countries and a one year survival rate of 40-50% in developing countries.
Anterior Mediastinal Pseudo-Tumor Tuberculosis: Should We Settle for This Diagnosis?
Mr M.Y., 32 years old, presented since 5 months Dyspnea associated with a productive cough, in a context of night sweats and encrypted weight loss 5 kg in 3 months and who has consulted in a different formation other than ours.
Primary Cutaneous Hodgkin Lymphoma: A Rare Disease Variant and Review of the Literature
A 49-year-old man presented with a 2-year history of an enlarging ulcerated plaque over the right forearm with an associated history of pruritus. Skin biopsy demonstrated an infiltrate of lymphocytes in the dermis and subcutis, together with atypical cells with large nuclei and prominent nucleoli resembling Reed-Sternberg cells.
Hepatic Dysfunction as Presenting Manifestation of Hodgkin’s lymphoma
Hepatic dysfunction is rarely the presenting feature of malignancy, however it is important to recognize early on as the quick institution of chemotherapy could potentially reverse the liver disease.
Giant Mucinous Cystadenoma in Adolescent – A Rare Case Report
A 13 year old, premenarchal, previously healthy girl presented to the emergency department of our hospital with complaints of vomiting, constipation and abdominal pain for past one day. The patient also complained of slowly increasing abdominal distension and mild abdominal discomfort since past four months.
Persisting Cough as the Single Presenting Symptom of an Intrathoracic Tumor in a Nine-Month-Old Child with Adenovirus Airway Infection
We report on a nine-month-old girl who presented with persisting cough, and diminished ventilation of the left hemithorax. Viral pneumonia was suspected after Adenovirus detection by PCR, but chest X-rays showed a persistent shadowing of the left hemithorax and persistent coughing despite clinical improvement. Because of the discrepancy between clinical and radiological signs further investigations by ultrasound and CT scan were performed, which visualized an intrathroracic tumor. Histopathology confirmed
diagnosis of a teratoma.
The Emergence of Multiple Myeloma in a Patient with Essential Thrombocythemia: A Case Report
Multiple myeloma is a neoplastic disease characterized by neoplastic proliferation of plasma cells and monoclonal protein expression and related tissue damage.In the presence of overt clinical signs, the disease can easily be diagnosed, however in order to diagnose atypical cases, further investigation is needed with high clinical suspicion.
Editorial Board Members Related to lymphoma
BRUCE D CHESON
Professor of Medicine
Division of Hematology and Oncology
Georgetown University Hospital
United States
Division of Hematology and Oncology
Georgetown University Hospital
United States
Khaldon Bodoor
Associate Professor
Department of Biotechnology and Genetic Engineering
Jordan University of Science and Technology
Jordan
Department of Biotechnology and Genetic Engineering
Jordan University of Science and Technology
Jordan
Nallasivam Palanisamy
Associate Professor
Michigan Center for Translational Pathology
University of Michigan
United States
Michigan Center for Translational Pathology
University of Michigan
United States
Markus Müschen
Professor
Department of Laboratory Medicine
University of California, San Francisco
United States
Department of Laboratory Medicine
University of California, San Francisco
United States
Steve A. Maxwell
Associate Professor
Department of Molecular and Cellular Medicine
Texas A&M Health Science Center
United States
Department of Molecular and Cellular Medicine
Texas A&M Health Science Center
United States