Articles Related to mL

Maize is the most important crop in Kenya and parts of Sub-Saharan Africa. However, yields are below potential due to abiotic and biotic constraints. One of the major biotic concerns is maize lethal necrosis disease (MLN), which causes up to 100% yield losses. MLN is caused by the synergistic infection of two viruses, Maize chlorotic mottle virus (MCMV) and a potyvirus, commonly Sugarcane mosaic virus (SCMV)

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The classical Fisher exact test [1], which is unconditionally the uniformly most powerful unbiased (UMPU) test, requires randomization at the critical value(s) to be of size α. Obviously, one needs a non-randomized version of this. Rejecting the null only if the test-statistic’s outcome is more extreme than the critical values, reduces the actual size considerably. The modified Fisher exact test introduced in [2] additionally rejects the null when the test attains the critical value c(t) and the randomization probability γ(t) (that depend on the total number of successes T) exceeds a threshold γ0, which is determined such that, for all values of the nuisance parameter, the size of the unconditional modified test is smaller, but as close as possible to α. This greatly improves the size and power of the test as compared to, for example, the conservative nonrandomized Fisher exact test, while controlling the Type 1 error rate.

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: Aiming to evaluate the recent theoretical postulates on tinnitus underscoring the role of thalamocortical neural tracts, the present study 1) explores Middle Latency Response (MLR) as a possible physiological measure of tinnitus: thus investigates the predicted exaggeration of Pa-Na, Na-Pb interpeak amplitudes in tinnitus patients and 2) explores MLR as a prognostic indicator of Tinnitus Retraining Therapy: thus evaluates possible decrease in Pa-Na & Na-Pb amplitude after 2weeks exposure to Tinnitus Retraining Therapy.

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Adenoid cystic carcinoma (ACC) is a rare epithelial neoplasm, that may affect the salivary glands. It comprises 30% of epithelial minor salivary gland tumors. We present the case of a 56-year-old non-smoking woman with no significant medical history. The MRI finds a lesional process involving the right hemi mandible, the right buccal floor, which extends towards the region of the masticators and infiltrates the submandibular gland. A bone biopsy of the mandible under general anesthesia was performed, showing an adenoid cystic carcinoma. After announcing the diagnosis to the patient, she refused any treatment

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The records of 1198 crossbred cattle sired by 68 bulls were analyzed to estimate breeding values of sires using animal model Restricted Maximum Likelihood (REML), best linear unbiased prediction (BLUP), least squares methods (LSM) and simple daughter average ( D ) sire evaluation methods. The error variance of breeding values of sires were estimated and used in computing the relative efficiency of different sire evaluation methods. In the present study the least squares methods (LSM) have the lower error variance for Age at First Calving (AFC), First lactation milk yield (FLMY) and Lifetime lactation length (LTLL), while (BLUP) methods have the lower error variance for First lactation period (FLP), First dry period (FDP), First calving interval (FCI), First service period (FSP) and Lifetime milk yield (TLMY) as compared to other methods and accordingly, it was adjudged the most efficient sire evaluation method. In the present study, the higher value of coefficient of variation showing, there was very large variation in the herd for most of the traits under study. It indicated that the BLUP method is the best over the other three methods because estimated value of relative efficiency by BLUP method had smaller values than that of the other three methods. On the basis of the error variances of breeding values of sires the BLUP method was found most efficient sire evaluation method.

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Benign metastasizing leiomyoma (BML) is a rare event that occurs in middle aged women with a history of uterine myomas. It is characterized by multiple leiomyomatous lesions in many tissues and organs, especially in the lungs. We report the case of 56 years old woman presenting chronic cough, hemoptysis and having a history of myomectomy for a uterine leiomyoma 6 years ago. Chest CT showed a right pulmonary process. The histological diagnosis was defined by bronchoscopy and biopsies. The surgery was not an option because of the bronchovascular extension of the tumor, so hormonal therapy was administrated to the patient. One year later, Chest CT showed that the tumor doesn’t increase.

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Acute myeloid leukemia (AML) is a heterogeneous disease. Therefore, various parameters are needed to classify this disease into subtypes. The commonly used method for diagnosis and classification is based on FAB criteria using morphology and cytochemical stains. For some of the categories, immunopheno typing is necessary. The aim of present study is to determine the frequency of various sub-types in acute myeloid leukemia using FAB criteria in our Sudanese population. This will aid in the correct diagnosis of acute leukemia and hence proper management of the patients.

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Trypanosoma evansi (T. evansi) infection causes wasting and fatal animal trypanosomosis. This study was aimed at determining the gross and histopathological alterations in donkeys experimentally infected with T. evansi and the effect of isometamidium chloride treatment. Apparently healthy donkeys (N=18) of mixed sexes were randomly assigned to 3 groups; A1 (Infected-untreated), A2 (Infected, isometamidium-treated) and B (Uninfected, control) of six animals each. Each animal in infected groups had about 2.0x106 T. evansi injected through the jugular vein. Parasitaemia levels were evaluated using HCT and Mice Inoculation Test (support test). Gross and histopathological examinations were also conducted post-infection and post-treatment.

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Down syndrome or constitutional trisomy 21 was linked to leukemia for the first time in a case report published in 1930 since then, down syndrome has been recognized as one of the most important leukemia – predisposing syndromes and patients with down syndrome and leukemia have unique clinical features and significant differences in treatment response toxicity profiles compared to patients without down syndrome.

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We report here for the first time the efficacy of pegylated interferon α2a (Peg-Ifn) as a therapy for patients with myelofibrosis and high blast counts. We treated four patients who were in an accelerated phase of myeloproliferative neoplasms or acute panmyelosis with myelofibrosis using only this drug.

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Neutrophil extracellular traps (NETs) have been proposed as vehicles for the sensitization of T cells by decreasing their activation threshold.

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The DNA mismatch repair (MMR) system is necessary for the maintenance of genomic stability. The MMR system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops (IDLs) and heterologies generated during DNA replication and recombination.

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Cholesterol is an amphipathic sterol compound that exerts both structural and physiological tasks in the plasma membrane of all eukaryotic cells. The planar and rigid structure of this molecule regulates the fluidity of the phospholipid bilayer and its permeability to solutes and ions.

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Leukemia during pregnancy is rare, posing a complex series of questions, including appropriate therapy and maternalcounseling. Management of chronic myelocytic leukemia (CML) during pregnancy is limited.

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The prevalence of childhood obesity has been increasing rapidly and there is general consensus that good nutritional practices and physical activity should be encouraged as early as possible in life. The aim of this study was to describe and to compare the current lifestyle and dietary pattern of normal weight (NW) and overweight + obese (OW+OB) male adolescents who are physically active.

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