Articles Related to marker
Biomarkers of Microbial Dysbiosis as Causative Agent of Acute Diarrhea in Dogs
Dysbiosis is microbial imbalance and mostly common in gastrointestinal tract [1]. There is a significant different of microbial communities in diarrheic cases more than healthy dogs’ comparison of gender & clinical signs. Clostridium species is mostly commonly genus found infectious animal cases of diarrhea and moreover in dog in other hand unclassified genus of Ruminococcaceae Bacteroidetes and Faecali bacterium were isolated. The microbiome functional gene content of (PICRUSt) with elevation gastric enzymes & increase titers infra structural proteins in acute diarrhea. Studies and data for dysbiosis with different intestinal disorders in dog associated with acute diarrhea or chronic is very limited.
Current study to evaluate microbial dysbiosis. The fecal microbiome, characterized by 655 pyrosequencing of the different genes, AU/CG. There was lower range of bacterial isolates from cases of acute diarrhea compared to animal variation with statistical analysis. Altered microbial imbalance in gut occur with the microbial communities for gastric infection.
Evaluation of System Usability Scale as A Marker of Non-Human Computer Interface’s Usability: A Sanitizer Container-Based Study
The use and the production of sanitizers have increased in the post-pandemic situation to prevent the further spread of COVID-19. Usability assessment of sanitizer containers is essentially required to evaluate the effectiveness, efficiency, and satisfactory use of the sanitizer containers. This study aimed to evaluate the system usability scale (SUS) as a marker of perceived usability of non-human computer interfaces, such as - sanitizer containers. The perceived usability of three types of sanitizer containers was evaluated using SUS. The authors have measured the reliability, convergent, and discriminant validity to evaluate SUS as a marker of usability of sanitizer containers. The result showed that SUS lacks convergent validity though it has a higher reliability coefficient. Thus, this is not the best measure of usability for non-human computer interfaces like-sanitizer containers. The SUS was applied on the flip cap, finger-pressure pump, and spray-type sanitizer containers. The finger-pressure pump container has exhibited a higher SUS score than others. The results of this study have given an idea about the usability of three different kinds of sanitizer containers. This research provides an overview of the application of SUS on non-Human computer interfaces like sanitizer containers. This study provides limitations like lack of convergent validity and ideas to overcome common method bias.
Early Predictive Value of MR-proADM in Critically Ill Patients with Covid-19: An Observational Study in the Emergency Department
Since December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has reached catastrophic proportions. Many patients required admission to the intensive care units (ICU), stressing the capacity of public health systems. The workload in the emergency departments (ED), especially the ICU, has dramatically increased, creating a pressing need to optimize resources through risk stratification for critically ill COVID-19 patients.
Standardization of Pro-Inflammatory Cytokines (IL-1 & TNF-α) and Haematological Biomarker as an Early Assessment of Health Status in Adult Healthy Pigs
The study was aimed to standardize pro-inflammatory cytokines and haematological biomarker level in visually adult healthy swine as an early health check-up scanner. In the present study, total six (6) crossbreed pigs (Yorkshire × Swedish Landrace) with similar age group (3 years) and unisex (male) with average body wt (140 kg) were selected for sampling.
Clinical Features and Management of Eosinophilic Asthma
Asthma is a common chronic airway disease affecting about 334 million people worldwide, and an estimated 7 million children
globally. Approximately 10% of patients with asthma have severe refractory disease, which is uncontrolled despite using high doses
of inhaled corticosteroids and other modifiers. Among these patients are patients with eosinophilic asthma. Eosinophilic asthma is a
phenotype of asthma that is usually very severe and persistent, with frequent exacerbations. It is characterized by the presence of high
levels of eosinophils, and CD+4 Th2 cells in the lungs and airways. Eosinophils play a pivotal role in the pathogenesis and severity
of asthma. Most patients with eosinophilic asthma respond to the classic stepwise guided treatment. However, 50% of patients with
eosinophilic asthma are refractory to corticosteroids and long-acting β2-agonists. Currently, there are targeted personalized biologics
for these patients. These biotherapeutics include IgE, interleukin and interleukin receptor monoclonal antibodies,they have added
advantageous steroid-sparing effects.
Impact of the Biofield Energy Healing Based Test Formulation on Various Health Biomarkers Using Cell-Based Assays
Various complementary approaches have been used against multiple organ dysfunction syndrome (MODS), which is the major
contributor in high mortality among the healthcare centers.
Profile of Newborns with Bone Metabolic Disease in a Neonatal Intensive Therapy Unit
This is a retrospective and documental study with a quantitative approach, performed at the NICU of a reference hospital in Fortaleza, from November 2016 to January 2017, whose sample consisted of 30 medical records. The following variables were analyzed: weight, gestational age (GI), weight / GI adequacy, gender, Apgar score, BDM associated morbidities, ventilator support, parenteral nutrition (NTP), medicines, physiotherapeutic assistance and blood biochemical analysis. The variables were analyzed by Microsoft
Excel® 2016 to obtain absolute and percentage data.
Variability of Morphological Markers of Cone and Seeds in Natural Populations and Artificial Plantations of the Scots Pine (Pinus sylvestris L.)
The variability of morphological markers of the reproductive organs in seven natural populations and nine artificial plantations of the Scots pine of Ukrainian Polissya (Volyn, Rivne and Kyiv regions) was studied. The colour of cones, seeds, winged seeds, and the apophysis of the cones of the trees were used as morphological markers.
Is there Correlations among SLEDAI, Pro-Inflammatory Biomarkers and Urine NGAL in SLE?
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune inflammatory disease. Several indexes can measure SLE activity, and Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) is one of them. The aim was to associate SLEDAI with inflammatory biomarkers present in serum (C3, C4, CH50, C-reactive protein, and creatinine), proteinuria (urine 24h) and urine NGAL in SLE patients. This study included 43 SLE patients who were arranged in two groups according to the value of SLEDAI. One group, SLEDAI 0-4 (n=25), included SLE patients with low activity, and the other group, SLEDAI >4 (n=18), included SLE patients form moderate to high activity. Level of urine NGAL (uNGAL) was determined by ELISA, and the data were analyzed using GraphPad Prism 5.
The Roles of IL-33 and TGF-Β1 in the Pathogenesis of Stevens-Johnson Syndrome/ Toxic Epidermal Necrolysis: Potential Biomarkers for Disease Severity
MicroscopyStevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a disease continuum of potentially life threatening, severe allergic drug reactions which result in cellular apoptosis in the skin, mucous membranes, and ocular surface. The exact pathophysiologic mechanisms leading to this apoptosis is unclear but genetic predisposition and abnormal immune regulations play a role.
Dynamic Institutionalization of Research in the Field of Colorectal Tumour Markers
Institutionalization and internationalization of modern interdisciplinary research belong to the essential components of scientific communications. Our purpose was to analyze scientometrically the dynamic science institutionalization on colorectal tumour markers as reflected in four information portals. In June 2017, a retrospective problem-oriented, title-word based search was performed in Web of Science Core Collection (WoS), MEDLINE and BIOSIS Citation Index (BIOSIS) of Web of Knowledge as well as in Scopus for 1987-2016.
Detection of the host-specific Bacterioides and Bifidobacteriumsaeculare markers in surface water in Hanam, Vietnam with real-time PCR
The microbiological quality of coastal or river waters can be affected by faecal pollution from human or animal sources. Contamination of fresh produce with pathogenic bacteria can be attributed directly or indirectly to the raw wastewater (domestic, industrial effluents, human and animal excrement). This includes water sources that are routinely used for crop irrigation and produce washing. An efficient MST (Microbial Source Tracking) toolbox consisting of several host-specific markers would, therefore, be valuable for identifying the origin of the faecal pollution in the environment and thus for effective resource management and remediation. As a result, the need for expanding from traditional techniques to molecular methods has been highly recommended.
Neurobiochemical Roles of Low Molecular Weight Antioxidants on Oxidative Stress Biomarkers and Severity of Ischemic Stroke in Wistar Rats
Purpose: To evaluate the neurobiochemical role(s) of low molecular weight (LMWA) antioxidants in the treatment of surgically- induced ischemic stroke (IS) in wistar rats.Methods: Ischemic stroke was induced in wistar rats using middle cerebral artery occlusion (MCAO). Neurological assessments were carried out using stair case, cylinder test and modified neurological severity score (mnss) methods. Low molecular weight antioxidants (vitamins C, E, α-lipoic acid, dimethyl sulfoxide and mannitol) were orally administered to the rats for two weeks in three different doses (22.5, 45 and 67.5 mg/kg).
A Randomized Double-Blind Placebo Controlled Clinical Trial Evaluating the Effects of an Investigational Study Product on Exercise Induced Muscle Soreness, Markers of Inflammation, Muscle Damage and Exercise Performance in Healthy Males
Gherkin, a pure botanical extract from cucumber is a phytonutrient rich vegetable which may have been shown to have anti-inflammatory and pain relieving properties. The purpose of this randomized double-blind placebo study was to determine the effects of Gherkin (Cuvitus™, Actido®)on exercise performance, markers of inflammation and acute muscle soreness in healthy males.
Relationship of YWHAH Single Nucleotide Polymorphisms to Markers of Rheumatoid Arthritis Disease Severity
Introduction: Serum 14-3-3 eta provides diagnostic and prognostic information in Rheumatoid Arthritis (RA). It is coded by the YWHAH gene with single nucleotide polymorphisms (SNPs) linked to bipolar disorder and schizophrenia. It was hypothesized that 6 previously described YWHAH SNPs might relate to markers of RA disease severity such as seropositivity or erosive changes.
Association study performed at an academic hospital Rheumatology Clinic. Subjects studied were 18 years of age or older with RA. TaqMan analysis screened for YWHAH SNPs rs2246704, rs2853884, rs3747158, rs4820059, rs7291050, rs933226. Primary endpoint was presence of at least one copy of the YWHAH SNPs with the markers of RA disease severity.
Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath
The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS
The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in
legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine
the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix),
polyester, rayon and wool.
Editorial Board Members Related to marker
Prof. Dr. Alireza Heidari, Ph.D., D.Sc.
Full Distinguished Professor and Academic Tenure of Chemistry.
Enrico Fermi Distinguished Chair in Molecular Spectroscopy.
Head of Cancer Research Institute (CRI).
Director of the Bio Spectroscopy Core Research Laboratory (BCRL) at Faculty of Chemistry, California South University (CSU), Irvine, California, USA.
President of the American International Standards Institute (AISI), Irvine, California, USA.
Board Member of the World Association of Theoretical and Computational Chemists (WATOC).
Alessia Giannetto
Researcher
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences
University of Messina
Italy
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences
University of Messina
Italy
Younes Chorfi
Associate Professor
Department of Veterinary Biomedicine
University of Montreal
Canada
Department of Veterinary Biomedicine
University of Montreal
Canada
Ock K. Chun
Assistant Professor
Department of Nutritional Sciences
University of Connecticut
United States
Md Mahmudul Hasan Khan, PhD
Genetics and Breeding Unit, Laboratory of Climate-Smart Food Crop Production, Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, UPM, Malaysia.
&
Scientific Officer (Genetics & Plant Breeding)
Bangladesh Agricultural Research Institute (BARI)
Under Ministry of Agriculture (MOA), Bangladesh.
Jianfei Qi
Assistant Professor
Biochemistry and Molecular Biology
University of Maryland School of Medicine
United States
Biochemistry and Molecular Biology
University of Maryland School of Medicine
United States