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Articles Related to masking

Falsely Low HbA1c Unmasking a Latent HbE Defec

The current case report illustrates role of vigilant laboratory services that helped in unmasking asymptomatic HbE variant in a middle aged known diabetic woman who came as an outdoor patient and on subsequent HbA1c testing was found to have lower value -2.9 %. It triggered extensive workup after looking for common causes and an electrophoresis of Hemoglobin revealed HbE variant.
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Nonparametric estimation of cumulative cause specific reversed hazard rates under masked causes of failure

In the analysis of competing risks data, it is common that the exact cause of failure for certain study subjects is missing. This problem of missing failure type may be due to inadequacy in the diagnostic mechanism or reluctance to report the exact cause of failure.
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Orally Disintegrating Tablets: A Short Review

This article summarizes the advantages of orally disintegrating tablets (ODTs) as well as critical issues during evaluation of ODTs such as bioequivalence and challenges and limitations of ODTs and finally present and the future of ODTs. ODTs have received everincreasing demand and the field has become a rapidly growing area in the pharmaceutical industry.
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Reduction of Bitterness and Enhancing Palatability of Cetirizine Oral Liquid Dosage Forms by Cyclodextrins

The aim of this manuscript is to study cyclodextrins (CDs) as a potential excipient to suppress bitterness and enhance palatability of pediatric liquid preparations for Cetirizine, an extremely bitter drug. Natural α, β and γ CDs; and β CD derivatives such as hydroxyl propyl (HP), randomly methylated (RM) and sulfobutyl ether (SBE) β-CDs were screened in different molar ratios of 1:1, 1:2 and 1:3 for their inhibition of the extremely bitter taste of Cetirizine using the human gustatory sensation test.
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