Articles Related to nerve

Background and Objective: Septic shock remains an impatient cause of morbidity and mortality. Early restitution of the circulation improve tissue oxygen delivery and increase survival. This study is a prospective randomized single center study its main objective is to investigate the therapeutic value of hypertonic saline in patients with septic shock. Methods: Fifty-two critically ill patients admitted with septic shock divided into two groups, the first group received isotonic saline (control group) starch, while the second received hypertonic saline 5%.

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Purpose: We aimed to create mechanic optic nerve injury model in rats and investigate the neuroprotective effects of ripasudil on retinal ganglion cells. Study Design: Experimental study Methods: Mechanic optic nerve injury model was created in the right eyes of male Wistar rats (n=15). Rats were divided into three groups: glaucoma model with sham treatment (group1) and 20 µM intravitreal ripasudil treatment (group 2) and 50 µM intravitreal ripasudil treatment (group 3). Treatment was applied intravitreally and rats were sacrificed at the end of 4 weeks. Glial fibrillary acidic protein (GFAP), Brn-3a antibody,anti- Iba1 was examined by immunohistochemistry. Results: The number of Brn-3a positive RGC in the mechanical optic nerve injury model was 5.33 ± 2.08 (min: 3, max: 7) in sham group, 10.25 ± 2.63 (min: 8, max: 14) in 20 µM group and 16.75 ± 5.43 (min:9, max: 21) in 50 µM group (p <0.05). GFAP positive RGC counts were recorded as 24.33 ± 2.08 (min: 22, max: 26) in sham group, 16.75 ± 1.70 (min: 15, max: 19) in 20 µM group and 13.00 ± 4.08 (min:10 , max: 19) in 50 µM group (p <0.05). Ripasudil treatment also decreased Iba1 expression in the retina of mechanic optic nerve injury groups. In addition, ripasudil treatment prevented apoptotic cell death by increasing Bcl-xL protein expression and preserved Tfam protein expression in the retina. Conclusions: Our experimental study has shown that ripasudil is neuropreotective in mechanical optic nerve injury model.

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Prevention of obstetric trauma from damage to the pelvic floor is not always possible and sacral nerve stimulation (SNS) may be necessary later in life. Sacral nerve stimulation has been a promising innovation in the management of moderate to severe faecal incontinence and following sphincter repair failure. Although the indication spectrum for SNS is expanding, the success of neuromodulation for constipation is limited. Adverse events of SNS requiring reintervention are not common but a long-term successful outcome may depend on interventions for maintenance of the device.

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SARS-CoV-2 can reach the central nervous system through the vagal nerve. Microbiota may favour or prevent viral spread. Assess whether auricular transcutaneous vagus nerve stimulation (ATVNS) may favour the occurrence of mild-COVID-19 or the recurrence of herpes simplex type 1. 749 patients were included. 195 patients were recommended and comply with ATVNS. 67 patients of the ATVNS group experienced mild-COVID-19 (34.3%) versus only 28 in the not-recommended ATVNS group (525 patients; 5.3%). A similar percentage was observed in the non-compliant ATVNS group (one case for 29 patients; 3.4%) [p<0.001].

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The aim of this study was to investigate the safety and feasibility of common carotid artery sympathetic nerve network stripping (CCASNS) combined with implanted vagus nerve stimulation (iVNS) for seizure control in children with cerebral palsy with refractory epilepsy. We reviewed the medical records of children with cerebral palsy with drugrefractory epilepsy treated at the Fifth Affiliated Hospital of Zhengzhou University from September 2015 to June 2019.

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A needle breakage is a rare complication of an inferior alveolar nerve block, but it should represent an awkward experience both for the patient and the dentist. A broken needle in the pterygo mandibular region would be hard to remove and it may also have important medico-legal considerations. This is the case report of a 32-years old man, referred by his own dentist to the Maxillo-Facial department, after the needle broke during the routine administration of an inferior alveolar nerve block for a dental procedure. In this paper, authors present the successful removal of the fractured needle from the right pterygomandibular region under general anesthesia administration.

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The aim of this study was to evaluate the cases of Isolated Third, Fourth and Sixth Cranial Nerve (CN) palsies of microvascular etiology in patients with Diabetes mellitus(Type2) and analyze their Glycosylated hemoglobin (HbA1c) levels. A retrospective study of patients diagnosed with third, fourth or sixth nerve palsy over three years, 2014- 2017 was done. 61 patients with the nerve palsy of microvascular ischaemic etiology due to diabetes mellitus(Type2) were selected for the study. The latest laboratory investigations that the patient had were recorded. The fasting, postprandial blood sugars and HbA1c levels were analyzed. Analysis was done using Microsoft excel 2010.

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Facial nerve paralysis may occur along the natural progression of an untreated vestibular schwannoma, as a surgical complication following vestibular schwannoma resection, or as a late sequela of stereotactic radiation. However, facial paralysis occurring as a subacute complication of CyberKnife (Accuray, Inc., Sunnyvale, CA, USA) stereotactic radiation has not previously been reported. A 47-year-old male presented with a right vestibular schwannoma measuring 3.1 cm in greatest dimension with House-Brackmann grade I/VI facial function and American Academy of Otolaryngology – Head and Neck Surgery class a hearing. After deferring surgery, he elected to undergo CyberKnife stereotactic radiation to a total dose of 18 Gy in three stages.

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Lumbosacral radicular pain (LRP) is a common symptom, its annual prevalence in the general population is reported to be from 9.9% to 25% and it is characterized by a shooting, radiating pain to one or more dermatomes, which is often caused by irritation of the corresponding nerve root. The initial treatment should be conservative with oral medications, exercise, and physiotherapy. When conservative treatments fail, epidural steroid injections and other interventional treatments should be considered. Surgical interventions are indicated when all other treatments have failed.

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A 54 year old female presented for atrial fibrillation (AF) catheter cryoablation. She had experienced multiple pre-syncopal episodes prior to diagnosis and underwent a cardiac work-up including Holter monitor, transthoracic echocardiogram,stress test and tilt table test which was negative except for atrial fibrillation. She presented to the hospital for an AF ablation procedure under general anesthesia after transesophageal echocardiogram to rule out atrial thrombosis formation.

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Schwannoma is a benign tumor that originates from the presence of Schwann cells of the peripheral nerves. They are usually asymptomatic, do not recur, and malignant transformation is rare.

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Hypoglossal schwannomas are rare cranial base neoplasm arising from schwann cells of the XIIth cranial nerve. We report a case of 45 year old lady with history of headache for 2 years and difficulty in swallowing for 1 year. On evaluation, she was found to have left hypoglossal paresis, atrophy of tongue muscles on left side and a smooth oropharyngeal bulge on left side.

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There could be progressive changes in hemodynamic and autonomic parameters causing cardiovascular damage from lean to morbid obesity. We aim to study resting and reactivity of hemodynamic and autonomic parameters to physical and mental stress in lean, overweight and obese subjects of the Oman Family Study (OFS).

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Parry-Romberg syndrome is a rare disorder characterized by slowly progressive deterioration of the skin and soft tissues of half of the face. The syndrome presents with characteristic skeletal, dental, and soft tissue changes in the affected half of the face, with or without neurological signs and symptoms.

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Closed traumatic rupture of extensor tendons of the fingers at the musculotendinous is rare. In fact the common sites of a closed rupture are distal attachment at the distal phalanx as well as at the attachment of the central slip at the base of the middle phalanx.

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