Articles Related to oxidative stress

Background to Study: Lead (Pb) is ubiquitous in the environment and toxic. It has many negative effects on many organs and induces biochemical, physiological, and behavioural alterations on the brain. Monodora myristica is a calabash nutmeg belonging to the family of Annonaceae.It is a rich source of flavonoids which have been shown to exhibit both antioxi-dant and anti-inflammatory properties. We evaluated the protective role of Monodora myristica on lead-induced toxicity in D. melanogaster in this study

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It was a cross-sectional study including 434 apparently healthy subjects (194 males) divided into two groups: i) obese (BMI ≥ 30 Kg/m²) and ii) non-obese (BMI < 30 Kg/m²). Exclusion criteria were: current smokers, asthma, medicine intake interfering with FeNO levels, and abnormal lung function tests. The FeNO measurements were performed before spirometry. Student t test was performed to compare between the two groups. The Spearman correlation between BMI and FeNO levels was evaluated. The Piecewise linear regression with breakpoint was assessed to define the breakpoint of inflammation related to obesity.

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The study was aimed to evaluate the antioxidant and antiaging potential of Biofield Energy Healing Treatment (the Trivedi Effect®) on a novel test formulation in in vitro. The test formulation was divided into two parts

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Purpose: To evaluate the neurobiochemical role(s) of low molecular weight (LMWA) antioxidants in the treatment of surgically- induced ischemic stroke (IS) in wistar rats.Methods: Ischemic stroke was induced in wistar rats using middle cerebral artery occlusion (MCAO). Neurological assessments were carried out using stair case, cylinder test and modified neurological severity score (mnss) methods. Low molecular weight antioxidants (vitamins C, E, α-lipoic acid, dimethyl sulfoxide and mannitol) were orally administered to the rats for two weeks in three different doses (22.5, 45 and 67.5 mg/kg).

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This paper aims to review in literature the main mechanisms of oxidative stress, pointing out the major formed metabolites, the mechanisms of cell damage and major antioxidants. Oxygen is essential to human life. The formation of free radicals (FR) is closely related to oxygen consumption, a mechanism that occurs with an incomplete reduction of this molecule.

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Cognitive waning due to chronic copper (Cu) intoxication in animal models is increasingly being reported; notwithstanding, information regarding molecular basis of Cu accumulation and neurobehavioral impairments remains fragmentary.

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