Articles Related to oxidative
Monodora Myristica Protects Against Oxidative Stress in the Drosophila Melanogaster Model of Lead-Induced Neurotoxicity
Background to Study: Lead (Pb) is ubiquitous in the environment and toxic. It has many negative effects on many organs
and induces biochemical, physiological, and behavioural alterations on the brain. Monodora myristica is a calabash nutmeg
belonging to the family of Annonaceae.It is a rich source of flavonoids which have been shown to exhibit both antioxi-dant
and anti-inflammatory properties. We evaluated the protective role of Monodora myristica on lead-induced toxicity in D.
melanogaster in this study
The Simultaneous Activation of Nrf2 and Antioxidant Compounds may reduce the Risk, Progression, and Improve the Management of Diabetes by Reducing Oxidative and Inflammatory Damages
Despite extensive research, the incidence of diabetes continues to increase, and the management of diabetes needs improvement, because in 2016, more than 100,000 patients had lower extremity amputated, suffered ischemic heart disease and stroke. Analysis of investigations indicates that increased oxidative stress and chronic inflammation enhance the risk, progression, diabetic–related complications, and reduce effectiveness of drug therapy. Therefore, simultaneously attenuation of these cellular abnormalities may help in reducing the risk of development, progression, and prolonging the effectiveness of drug therapy.
Fractional Exhaled Nitric Oxide (FeNO) in Healthy Obese Adults
It was a cross-sectional study including 434 apparently healthy subjects (194 males) divided into two groups: i) obese (BMI ≥ 30 Kg/m²) and ii) non-obese (BMI < 30 Kg/m²). Exclusion criteria were: current smokers, asthma, medicine intake interfering with FeNO levels, and abnormal lung function tests. The FeNO measurements were performed before spirometry. Student t test was performed to compare between the two groups. The Spearman correlation between BMI and FeNO levels was evaluated. The Piecewise linear regression with breakpoint was assessed to define the breakpoint of inflammation related to obesity.
Evaluation of Anti-aging Effect of the Novel Test Formulation in Cell-based Studies using Β-Galactosidase Activity, Collagen Levels, and Protection against Oxidative Stress
The study was aimed to evaluate the antioxidant and antiaging potential of Biofield Energy Healing Treatment (the Trivedi Effect®)
on a novel test formulation in in vitro. The test formulation was divided into two parts
A Novel Neuroprotective and Antioxidative Efficacy of a Unique Combination of Standardized Huperzia serrata, Convolvulus pluricaulis and Celastrus paniculatus Extracts
Physical and environmental stress in conjunction with hectic lifestyle and unhealthy food habits are the major cause of diverse neurodegenerative disorders. Oxidative neuronal injury and acetylcholine deficiency have a major impact on learning and memory retention. Most of the treatment strategies are based on the improvement of cholinergic function in the brain and one of the emerging therapeutic targets is to enhance the acetylcholine level in the brain. Standardized botanical extracts including Huperzia serrata (1% Huperzine A, CogniUp), Convolvulus pluricaulis (SP) and Celastrus paniculatus (JY) have been demonstrated to attenuate brain function by serving as a natural acetylcholinesterase (AChE) inhibitor.
The Use of Near-Infrared Spectroscopy in the Sport-Scientific Context
The focus of this research is aimed specifically at the application of near-infrared spectroscopy (NIRS) in exercise and sport science. NIRS is able to monitor the performance of muscle and cerebral tissue and evaluate their role during physical activity. By monitoring tissue oxygenation, an NIRS device is useful in several areas, which may benefit from its applications.
Neurobiochemical Roles of Low Molecular Weight Antioxidants on Oxidative Stress Biomarkers and Severity of Ischemic Stroke in Wistar Rats
Purpose: To evaluate the neurobiochemical role(s) of low molecular weight (LMWA) antioxidants in the treatment of surgically- induced ischemic stroke (IS) in wistar rats.Methods: Ischemic stroke was induced in wistar rats using middle cerebral artery occlusion (MCAO). Neurological assessments were carried out using stair case, cylinder test and modified neurological severity score (mnss) methods. Low molecular weight antioxidants (vitamins C, E, α-lipoic acid, dimethyl sulfoxide and mannitol) were orally administered to the rats for two weeks in three different doses (22.5, 45 and 67.5 mg/kg).
Mitochondrial Production of Perhydroxyl Radical (HO2 • ) as Inducer of Aging and Age-Related Pathologies
All organisms age, in the search of the universal mechanisms of aging Barja analyzed results obtained with various species of mammals and birds and concluded that only two known factors correlate in the right sense (inversely) with animal longevity in vertebrates: the long life span is associated with (a) low rates of mitochondrial reactive oxygen species production, and (b) low degree of fatty acid polyunsaturation of cellular membranes including the mitochondrial ones [Barja (2014) Prog Mol Biol Transl Sci. 127:1-27].
Mitochondrial Actions for Fat Browning and Energy Expenditure in White Adipose Tissue
White adipose tissue (WAT) is an endocrine organ with crucial role in the development of obesity and related diseases. White adipocytes have less mitochondria than brown adipocytes; nevertheless, there is an increasing body of evidence showing that mitochondrial parameters play a relevant role in WAT physiology, such as proliferation, differentiation and triacylglycerol storage levels.
The Role of Nutrition in Fighting Free Radicals
This paper aims to review in literature the main mechanisms of oxidative stress, pointing out the major formed metabolites, the mechanisms of cell damage and major antioxidants. Oxygen is essential to human life. The formation of free radicals (FR) is closely related to oxygen consumption, a mechanism that occurs with an incomplete reduction of this molecule.
Antifungal Potential in Crude Extracts of Five Selected Brown Seaweeds Collected from the Western Libya Coast
The present study confirms the potential use of seaweed extracts as a source of antifungal compound and may constitute a basis for promising future applied research that could investigate the use of seaweeds.
Expression Profile of Hepatic Metallothionein-I and ATP7B, and Brain Metallothionein-III and Acetyl cholinesterase Genes in Wistar Rat Model for Non-Wilsonian Brain Copper Toxicosis
Cognitive waning due to chronic copper (Cu) intoxication in animal models is increasingly being reported; notwithstanding, information regarding molecular basis of Cu accumulation and neurobehavioral impairments remains fragmentary.
Anti-Arthritic Efficacy And Safety Of Crominex 3+ (Trivalent Chromium, Phyllanthus emblica Extract, And Shilajit) In Moderately Arthritic Dogs
The present investigation was undertaken to evaluate the therapeutic efficacy and safety of Crominex 3+ (a complex of trivalent chromium, Phyllanthus emblica (Amla) extract and purified Shilajit) in moderately arthritic dogs.
Topical Delivery System for Phytochemicals: Capsaicin and Capsicum Tincture
Capsaicin, an active ingredient of Capsicum fruit, is currently undergoing “revival” in the clinical management of pain. However, the choice of its formulation is rather limited to the use of “old-fashioned” tinctures and recently the patches. In an attempt to improve the therapeutic outcome and develop its skin-friendly formulation, we prepared the vesicle-based drug delivery system with capsaicin.
Editorial Board Members Related to oxidative
Hong Zhu
Associate Professor
Campbell University School of Osteopathic Medicine
United States
Campbell University School of Osteopathic Medicine
United States
Saul Yedgar
Professor
Department of Biochemistry
Hebrew University
Israel
Department of Biochemistry
Hebrew University
Israel
Seyed Khosrow Tayebati
Professor
Department of Experimental Medicine and Public Health
University of Camerino
Italy
Department of Experimental Medicine and Public Health
University of Camerino
Italy
Lufang Zhou
Lufang Zhou
Assistant Professor
The University of Alabama
Birmingham
United Kingdom
Assistant Professor
The University of Alabama
Birmingham
United Kingdom
Chiang-Ting Chien
Professor
Department of Biology
National Taiwan Normal University
Taiwan
Department of Biology
National Taiwan Normal University
Taiwan
Mohsen Meydani
Professor
Friedman School of Nutrition Science and Policy
Tufts University
United States
Friedman School of Nutrition Science and Policy
Tufts University
United States
YUNBO LI
Professor
Department of Pharmacology
Campbell University School of Osteopathic Medicine
United States
Department of Pharmacology
Campbell University School of Osteopathic Medicine
United States
Aladin M Boriek
Professor
Department of Medicine
Baylor College of Medicine
United States
Department of Medicine
Baylor College of Medicine
United States
Zeliha Selamoglu
Professor
Department of Medical Biology
Faculty of Medicine
Nigde Ömer Halisdemir University Campus
Turkey
Department of Medical Biology
Faculty of Medicine
Nigde Ömer Halisdemir University Campus
Turkey
Angela Myracle
Assistant Professor
School of Food and Agriculture
University of Maine
United States
School of Food and Agriculture
University of Maine
United States