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Articles Related to pain

Impact of Inverted Interrupted Skin Suturing Versus Continous Suturing in Episiotomy on Postpartum Pain in Primigravida

Episiotomy is an incision that is made in perineum at the end of part of second stage of delivery. There are Long term sequels of episiotomy repair. A considerable number of ladies complains from perineal pain and up to twenty percent have long term complications e.g., dyspareunia [1]. The best method for repairing episiotomy is the method that isnot time consuming and lesser materials and causes lesser pain in the immediate and long term periods.
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The Use of Gingipain DNA Vaccine Against Virulence of Porphyromonas Gingivalis: A Literature Review

Porphyromonas gingivalis (P. gingivalis) is a primary etiologic agent of generalized aggressive and chronic forms of periodontitis. It releases toxins called ‘gingipains’.Gingipains, (Arginine-and Lysine-specific cysteine proteinases) are proteases that are critical virulence factors in progression of periodontitis and degradation of cytokines expressed during inflammation. HRgpA and RgpB (products of two distinct but related genes) induce vascular permeability by activation of the kallikrein/kinin pathway and activating the blood coagulation system which in turn induces gingival crevicular fluid production and progression of inflammation leading to alveolar bone loss.
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Management-of-Postoperative-Pain-in-Patients-Undergoing-Surgery-for-Mandibular-Fracture

The mandible is one of the most frequently fractured bones in the facial skeleton. Postoperative pain control is an important outcome in assessing overall treatment success and patient satisfaction. However, few focused studies have reviewed protocols for postoperative pain management in patients with mandibular trauma. The aim of this study is to evaluate the protocol for the management of postoperative pain in patients undergoing surgery for a mandibular fracture in our department.
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A Randomized Double-Blind Placebo Controlled Clinical Trial Evaluating the Effects of an Investigational Study Product on Exercise Induced Muscle Soreness, Markers of Inflammation, Muscle Damage and Exercise Performance in Healthy Males

Gherkin, a pure botanical extract from cucumber is a phytonutrient rich vegetable which may have been shown to have anti-inflammatory and pain relieving properties. The purpose of this randomized double-blind placebo study was to determine the effects of Gherkin (Cuvitus™, Actido®)on exercise performance, markers of inflammation and acute muscle soreness in healthy males.
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Chronic Pain – Can It Be Cured?

Chronic pain is currently treated with several drugs and therapies that can be helpful, but usually do not cure chronic pain. In fact, many drug therapies make the pain worse or are toxic to the patient. Chronic pain treatment frequently involves oral or injected drugs because the perception is that chronic pain comes from an internal source. Chronic pain, and all other forms of pain, should be treated in the skin. Mechanisms of induction of chronic pain will be discussed and skin targets for the treatment and cure of chronic pain will be presented.
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Update on the Importance of Medical Education in the Changing Field of Pain Medicine

Chronic pain is a pandemic that has spawned the disproportionate opioid epidemic of overuse and overprescription in the United States. This challenge warrants review of physician education and curriculum to become more effective in pain management. Our current system for educating present and future physicians, as well as pain specialists, is flawed in a number of ways. The vast majority of physicians will encounter and manage chronic pain patients during their careers, but reviews have demonstrated dissatisfaction among medical students and practitioners with pain education and curriculum.
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Treatment of Chronic Back Pain with Radiculopathy by Selective Nerve Root Block or Pulsed Radiofrequency - Randomised, Open Label, Clinical Trial

Lumbosacral radicular pain (LRP) is a common symptom, its annual prevalence in the general population is reported to be from 9.9% to 25% and it is characterized by a shooting, radiating pain to one or more dermatomes, which is often caused by irritation of the corresponding nerve root. The initial treatment should be conservative with oral medications, exercise, and physiotherapy. When conservative treatments fail, epidural steroid injections and other interventional treatments should be considered. Surgical interventions are indicated when all other treatments have failed.
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Fatal road accidents in Spain: psychoactive substances in killed drivers in 2014

Road traffic accidents (RTAs) are often related to impairment by alcohol or drugs. The objectives of this study is to present toxicological data on drivers killed in traffic accidents in Spain in 2014 from a sample of 614 drivers and 240 (out of 614) with positive results for alcohol, illicit drugs and psychoactive medicinal drugs.
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Case Report of Severe Preeclampsia and Associated Postpartum Complications

Preeclampsia is clinically defined by hypertension and proteinuria, with or without pathologic edema that occurs after 20 weeks’ gestation, but can also present up to 4-6 weeks post-partum. Worldwide, incidence of preeclampsia is 5-14 percent of all pregnancies, while severe preeclampsia can develop to about 25 percent of all cases of preeclampsia.
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Serum Haptoglobin Responses following Rumenotomy in the Sahel Goat

Fifteen Sahel goats were randomly allocated into three groups A, B and C to evaluate Serum Haptoglobin (Hp) profiles following rumenotomy as markers of surgical stress using Quantitative ELISA.
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Hepatic Dysfunction as Presenting Manifestation of Hodgkin’s lymphoma

Hepatic dysfunction is rarely the presenting feature of malignancy, however it is important to recognize early on as the quick institution of chemotherapy could potentially reverse the liver disease.
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Unusual Presentation of Flexor Tendon Sheath Massive Ganglion

We report a unusual case of a flexor tendon sheath ganglion in a 78 years old, right hand dominant female presented with right little finger large multiloculated swelling involving the whole volar aspect of the little finger leaving the patient with fears of malignancy, swollen finger with limited mobility and distal tip numbness.
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Closed Traumatic Avulsion of Extensor Digitorium Communis and Extensor Indicis Proprius of Index Finger at the Musculotendinous Junction

Closed traumatic rupture of extensor tendons of the fingers at the musculotendinous is rare. In fact the common sites of a closed rupture are distal attachment at the distal phalanx as well as at the attachment of the central slip at the base of the middle phalanx.
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Giant Mucinous Cystadenoma in Adolescent – A Rare Case Report

A 13 year old, premenarchal, previously healthy girl presented to the emergency department of our hospital with complaints of vomiting, constipation and abdominal pain for past one day. The patient also complained of slowly increasing abdominal distension and mild abdominal discomfort since past four months.
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The Effect of Meloxicam NSAID Therapy on the Change in Vigor, Suckling Reflex, Blood Gas Measures, Milk Intake and Other Variables in Newborn Dairy Calves

The objective of this research was to determine the effect of the administration of meloxicam to newborn dairy calves on physiological and behavioral measures of calf vigor, as well as future health, milk intake and growth. A total of 284 Holstein heifer and bull calves were enrolled at birth from two dairy farms to participate in this randomized double-blind clinical field trial.
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Editorial Board Members Related to pain

Joseph Pergolizzi

Adjunct Assistant Professor
Department of Medicine
Johns Hopkins University
United States

Mirosław Kwiatkowski

AGH University of Science and Technology
Faculty of Energy and Fuels
Poland

Jorge Cerezal Garrido

Associate Professor
Department of Surgery
Medical school of the University Miguel Hernandez
Spain

Ana Rita Ramalho Figueiras

Faculty of Pharmacy
University of Coimbra
Portugal

Alemany Immaculate Arrebola

Professor
Department of Evolutionary Psychology and Education
University of Granada
Spain

Farnad Imani

Professor
Department of Anesthesiology
University Iran University of Medical Sciences
Iran

Rafael Luque

Professor
Department of Organic Chemistry
University of Cordoba
Spain

Jason J. Guo

Associate Professor
Center for Drug Discovery
Northeastern University
United States

Mohamed Khayet

Professor
Department of Applied Physics
Complutense University of Madrid
Spain

Alfonso Caracuel

Assistant Professor
Department of Psychology and Education
University of Granada
Spain
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