Articles Related to pathogenesis
Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Twin Sisters after Ibuprofen Administration. New Insights in Pathogenesis and Literature Review
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are closely-related, severe, acute life-threatening, drug-induced skin and mucosal disorders with a high mortality rate or long-term damages. These medical conditions are considered a delayed, typeIV hypersensitivity reaction and can be triggered by drugs, infections and malignancies.
The Roles of IL-33 and TGF-Β1 in the Pathogenesis of Stevens-Johnson Syndrome/ Toxic Epidermal Necrolysis: Potential Biomarkers for Disease Severity
MicroscopyStevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a disease continuum of potentially life threatening, severe allergic drug reactions which result in cellular apoptosis in the skin, mucous membranes, and ocular surface. The exact pathophysiologic mechanisms leading to this apoptosis is unclear but genetic predisposition and abnormal immune regulations play a role.
Dawn of the Biofilm Disease: Highlights about Biofilm in Bone and Joint & Prosthetic Joint Infections Pathogenesis, Diagnosis and Treatment
I present some key considerations of the biofilm disease as part of two complex pathologies such as bone and joint infections and prosthetic joint infections, taking into account the bacterial pathogenic factors to understand the particular nature of these infections, and to achieve an accurate diagnosis and management beyond the antimicrobial therapy. I mention some personal experience of many years in the medical microbiology laboratory and next to the patient’s bed.
Salmonella Serovars and Their Host Specificity
Salmonella is a causative agent for a wide variety of pathological diseases in humans, cattle, poultry and other farm animals and hence Salmonella infections are a major cause of concern to humans, veterinary animals and to food industry.
New Adipocytokines
They are cytokines secreted by adipose tissue considered to be immunomodulating agents, however they can be more accurately put into the larger, growing list of adipose-derived hormones.
MAPK Pathway in Skeletal Muscle Diseases
Mitogen-Activated Protein Kinase (MAPK) pathway is a signal transduction pathway that functions in a wide range of physiological and pathophysiological cellular events including cell proliferation, differentiation, apoptosis, migration, inflammation, metabolic disorders and diseases.
Editorial Board Members Related to pathogenesis
UDAI P. SINGH
Associate Professor
Department of Pathology, Microbiology and Immunology
University of South Carolina
United States
Department of Pathology, Microbiology and Immunology
University of South Carolina
United States
MICHAEL VAN DOREN JOHNSTON
Professor
Department of Neurology and Pediatrics
Johns Hopkins University School of Medicine
United States
Department of Neurology and Pediatrics
Johns Hopkins University School of Medicine
United States
Yosra A. Helmy
Research Associate
Department of Veterinary Preventive Medicine
Food Animal Health Research Program
The Ohio State University
USA
Department of Veterinary Preventive Medicine
Food Animal Health Research Program
The Ohio State University
USA
JUAN CARLOS SALAZAR
Professor and Chair, Department of Pediatrics
University of Connecticut School of Medicine
Physician in Chief Connecticut Children’s Medical Center
Academic Director, Division of Pediatric Infectious Diseases and
Director of the Pediatric and Youth HIV Program
United States
University of Connecticut School of Medicine
Physician in Chief Connecticut Children’s Medical Center
Academic Director, Division of Pediatric Infectious Diseases and
Director of the Pediatric and Youth HIV Program
United States
Yosra A. Mohamed
Research Associate
Department of Veterinary Preventive Medicine
The Ohio State University
USA
Department of Veterinary Preventive Medicine
The Ohio State University
USA
PERNG GUEY CHUEN
Associate Professor
Department of Microbiology and Immunology
National Cheng Kung University
Taiwan
Department of Microbiology and Immunology
National Cheng Kung University
Taiwan
Li-Ru Zhao
Associate Professor
Department of Neurosurgery SUNY Upstate Medical University
United States
Department of Neurosurgery SUNY Upstate Medical University
United States
David Paul Richman
Professor
Department of Neurology and Center for Neuroscience
University of California
United States
Department of Neurology and Center for Neuroscience
University of California
United States