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Articles Related to pathogenesis

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Twin Sisters after Ibuprofen Administration. New Insights in Pathogenesis and Literature Review

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are closely-related, severe, acute life-threatening, drug-induced skin and mucosal disorders with a high mortality rate or long-term damages. These medical conditions are considered a delayed, typeIV hypersensitivity reaction and can be triggered by drugs, infections and malignancies.
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Etiologic Factors of the Periodontal Disease Pathogenesis

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The Roles of IL-33 and TGF-Β1 in the Pathogenesis of Stevens-Johnson Syndrome/ Toxic Epidermal Necrolysis: Potential Biomarkers for Disease Severity

MicroscopyStevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a disease continuum of potentially life threatening, severe allergic drug reactions which result in cellular apoptosis in the skin, mucous membranes, and ocular surface. The exact pathophysiologic mechanisms leading to this apoptosis is unclear but genetic predisposition and abnormal immune regulations play a role.
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Dawn of the Biofilm Disease: Highlights about Biofilm in Bone and Joint & Prosthetic Joint Infections Pathogenesis, Diagnosis and Treatment

I present some key considerations of the biofilm disease as part of two complex pathologies such as bone and joint infections and prosthetic joint infections, taking into account the bacterial pathogenic factors to understand the particular nature of these infections, and to achieve an accurate diagnosis and management beyond the antimicrobial therapy. I mention some personal experience of many years in the medical microbiology laboratory and next to the patient’s bed.
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Salmonella Serovars and Their Host Specificity

Salmonella is a causative agent for a wide variety of pathological diseases in humans, cattle, poultry and other farm animals and hence Salmonella infections are a major cause of concern to humans, veterinary animals and to food industry.
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New Adipocytokines

They are cytokines secreted by adipose tissue considered to be immunomodulating agents, however they can be more accurately put into the larger, growing list of adipose-derived hormones.
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MAPK Pathway in Skeletal Muscle Diseases

Mitogen-Activated Protein Kinase (MAPK) pathway is a signal transduction pathway that functions in a wide range of physiological and pathophysiological cellular events including cell proliferation, differentiation, apoptosis, migration, inflammation, metabolic disorders and diseases.
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Editorial Board Members Related to pathogenesis

UDAI P. SINGH

Associate Professor
Department of Pathology, Microbiology and Immunology
University of South Carolina
United States

Jason X. Cheng

Assistant Professor
Department of Pathology, Hematopathology
University of Chicago
United states

Walter Royal

Professor
Department of Neurology
University of Maryland
United States

ASISH K. SAHA

Associate Professor
Department of Medicine
Boston University
United States

ALBA A. TRESPALACIOS

Professor
Department of Microbiology
Pontificia Universidad Javeriana
Colombia

Zafar K. Khan

Professor
Department of Microbiology and Immunology
Drexel University
United States

JING LIN

Associate Professor
Department of Pediatrics
The Icahn School of Medicine at Mount Sinai
United States

Mamatha Ballal

Professor
Melaka Manipal Medical College
Manipal University
India

Kenneth Cheng

Assistant Professor
Department of Medicine
Hong Kong University
Hong Kong

LEONID B. MARGOLIS

Visiting Professor
Ilia University
Republic of Georgia
Georgia
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