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Articles Related to pathways

Predicting Multi-Drug Inhibition Interactions based on Signaling Networks and Single Drug Dose-Response Information

Inhibiting multiple pathways/targets with combination drug therapies is widely used to maximize therapeutic benefit in many diseases. Therapeutic success can often be improved by concurrently and/or sequentially inhibiting multiple pathways/targets by combining drugs with different mechanisms of action.
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The Effect of Interleukin-6-Type Cytokines and Adiponectin on MAPK Activation in the Immortalized Human Chondrocyte C28/I2 Line and Normal Human Chondrocytes

The C28/I2 line of immortalized juvenile human chondrocytes was employed to determine the extent to which recombinant human (rh) interleukin-6 (rhIL-6), the interleukin-6-like cytokine, rh-oncostatin M, and the adipokine, rh-adiponectin, activated extracellularsignal regulated kinase (ERK1/2), p38α mitogen-activated protein kinase (p38α MAPK) and c-Jun-amino-terminal kinase (JNK).
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Perspectives and Potential Applications of Ruthenium-Based Nanocarriers for Cancer Therapy

Cancer is a highly heterogeneous disease characterised by continuous uncontrolled growth and expansion of abnormal cells. In general, in tumor cells the signalling pathways regulating cellular processes, as cell growth and division and cell to cellcommunication result strongly altered.
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Editorial Board Members Related to pathways

RICHARD G. MOORE

Professor
Department of Obstetrics and Gynecology
Warren Alpert Medical School
Brown University
United States

HONGYU LI

Associate Professor
Department of Gastroenterology
Shenyang Northern Hospital
China

Frank Portugal

Associate Professor
Department of Biology
The Catholic University of America
United States

Dong-Hua Yang

Assistant Professor
Fox Chase Cancer Center
United States

Jianfei Qi

Assistant Professor
Biochemistry and Molecular Biology
University of Maryland School of Medicine
United States

Robert R. Redfield

Professor
Department of Immunology and Microbiology
University of Maryland
United States

Danail Bonchev

Professor
Center for the Study of Biological Complexity
Virginia Commonwealth University
United States

Faisal Aziz

Postdoc Research Fellow
Hormel Cancer Institute
China & USA

Eugene S. Kim

Associate Professor
Department of Surgery
University of Southern California
United States

Suman Sirimulla

Assistant Professor
Department of Basic Sciences
St. Louis College of Pharmacy
St. Louis, MO
United States.
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