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Articles Related to pathways

Predicting Multi-Drug Inhibition Interactions based on Signaling Networks and Single Drug Dose-Response Information

Inhibiting multiple pathways/targets with combination drug therapies is widely used to maximize therapeutic benefit in many diseases. Therapeutic success can often be improved by concurrently and/or sequentially inhibiting multiple pathways/targets by combining drugs with different mechanisms of action.
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The Effect of Interleukin-6-Type Cytokines and Adiponectin on MAPK Activation in the Immortalized Human Chondrocyte C28/I2 Line and Normal Human Chondrocytes

The C28/I2 line of immortalized juvenile human chondrocytes was employed to determine the extent to which recombinant human (rh) interleukin-6 (rhIL-6), the interleukin-6-like cytokine, rh-oncostatin M, and the adipokine, rh-adiponectin, activated extracellularsignal regulated kinase (ERK1/2), p38α mitogen-activated protein kinase (p38α MAPK) and c-Jun-amino-terminal kinase (JNK).
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Perspectives and Potential Applications of Ruthenium-Based Nanocarriers for Cancer Therapy

Cancer is a highly heterogeneous disease characterised by continuous uncontrolled growth and expansion of abnormal cells. In general, in tumor cells the signalling pathways regulating cellular processes, as cell growth and division and cell to cellcommunication result strongly altered.
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Editorial Board Members Related to pathways

Yue Chen

Assistant Professor
Department of Biochemistry, Molecular Biology and Biophysics,
University of Minnesota
United States

Danail Bonchev

Center for the Study of Biological Complexity
Virginia Commonwealth University
United States

Marc Poirot

Research Director at INSERM
Cancer Research Center of Toulouse
University of Toulouse

Aladin M Boriek

Department of Medicine
Baylor College of Medicine
United States

Nagendra K. Prasad

Assistant Professor
Division of Hematology and Oncology
Indiana University School of Medicine
United States

Kam C. Yeung

Associate Professor
Department of Biochemistry & Cancer Biology
University of Toledo College of Medicine
United States

Noah Isakov

Department of Microbiology and Immunology and the Cancer Research Center
Ben Gurion University of the Negev

Yinghao Wu

Assistant Professor
Department of Systems & Computational Biology
Yeshiva University
United States


Centre for Advanced Computational Solutions
Lincoln University
New Zealand

Nilesh W Gaikwad

Assistant Professor
Department of Nutrition/Environmental Toxicology
University of California, Davis
United States
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