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Articles Related to pathways

Predicting Multi-Drug Inhibition Interactions based on Signaling Networks and Single Drug Dose-Response Information

Inhibiting multiple pathways/targets with combination drug therapies is widely used to maximize therapeutic benefit in many diseases. Therapeutic success can often be improved by concurrently and/or sequentially inhibiting multiple pathways/targets by combining drugs with different mechanisms of action.
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The Effect of Interleukin-6-Type Cytokines and Adiponectin on MAPK Activation in the Immortalized Human Chondrocyte C28/I2 Line and Normal Human Chondrocytes

The C28/I2 line of immortalized juvenile human chondrocytes was employed to determine the extent to which recombinant human (rh) interleukin-6 (rhIL-6), the interleukin-6-like cytokine, rh-oncostatin M, and the adipokine, rh-adiponectin, activated extracellularsignal regulated kinase (ERK1/2), p38α mitogen-activated protein kinase (p38α MAPK) and c-Jun-amino-terminal kinase (JNK).
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Perspectives and Potential Applications of Ruthenium-Based Nanocarriers for Cancer Therapy

Cancer is a highly heterogeneous disease characterised by continuous uncontrolled growth and expansion of abnormal cells. In general, in tumor cells the signalling pathways regulating cellular processes, as cell growth and division and cell to cellcommunication result strongly altered.
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Editorial Board Members Related to pathways

Frank Portugal

Associate Professor
Department of Biology
The Catholic University of America
United States

Robert R. Redfield

Professor
Department of Immunology and Microbiology
University of Maryland
United States

Aladin M Boriek

Professor
Department of Medicine
Baylor College of Medicine
United States

Noah Isakov

Professor
Department of Microbiology and Immunology and the Cancer Research Center
Ben Gurion University of the Negev
Israel

Shi J. Liu

Professor
Department of Pharmaceutical Sciences
University of Arkansas for Medical Sciences
United States

HARRY E. RUDA

Professor
Department of Materials Science and Engineering
University of Toronto
Canada

Marc Poirot

Research Director at INSERM
Cancer Research Center of Toulouse
University of Toulouse
France

Danail Bonchev

Professor
Center for the Study of Biological Complexity
Virginia Commonwealth University
United States

Jianfei Qi

Assistant Professor
Biochemistry and Molecular Biology
University of Maryland School of Medicine
United States

Yinghao Wu

Assistant Professor
Department of Systems & Computational Biology
Yeshiva University
United States
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