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Articles Related to pathways

Predicting Multi-Drug Inhibition Interactions based on Signaling Networks and Single Drug Dose-Response Information

Inhibiting multiple pathways/targets with combination drug therapies is widely used to maximize therapeutic benefit in many diseases. Therapeutic success can often be improved by concurrently and/or sequentially inhibiting multiple pathways/targets by combining drugs with different mechanisms of action.
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The Effect of Interleukin-6-Type Cytokines and Adiponectin on MAPK Activation in the Immortalized Human Chondrocyte C28/I2 Line and Normal Human Chondrocytes

The C28/I2 line of immortalized juvenile human chondrocytes was employed to determine the extent to which recombinant human (rh) interleukin-6 (rhIL-6), the interleukin-6-like cytokine, rh-oncostatin M, and the adipokine, rh-adiponectin, activated extracellularsignal regulated kinase (ERK1/2), p38α mitogen-activated protein kinase (p38α MAPK) and c-Jun-amino-terminal kinase (JNK).
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Perspectives and Potential Applications of Ruthenium-Based Nanocarriers for Cancer Therapy

Cancer is a highly heterogeneous disease characterised by continuous uncontrolled growth and expansion of abnormal cells. In general, in tumor cells the signalling pathways regulating cellular processes, as cell growth and division and cell to cellcommunication result strongly altered.
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Editorial Board Members Related to pathways

DON KULASIRI

Professor
Centre for Advanced Computational Solutions
Lincoln University
New Zealand

Christophe P. Ribelayga

Associate Professor
Ophthalmology & Visual Science
The University of Texas Health Science Center
USA

P. S. SURESH

Assistant Professor
Department of Bio-Sciences
Mangalore University
India

Suman Sirimulla

Assistant Professor
Department of Basic Sciences
St. Louis College of Pharmacy
St. Louis, MO
United States.

Charles J. Malemud

Professor
Department of Medicine and Anatomy
Case Western Reserve University
United States

Noah Isakov

Professor
Department of Microbiology and Immunology and the Cancer Research Center
Ben Gurion University of the Negev
Israel

Nilesh W Gaikwad

Assistant Professor
Department of Nutrition/Environmental Toxicology
University of California, Davis
United States

Yue Chen

Assistant Professor
Department of Biochemistry, Molecular Biology and Biophysics,
University of Minnesota
United States

HONGYU LI

Associate Professor
Department of Gastroenterology
Shenyang Northern Hospital
China

Danail Bonchev

Professor
Center for the Study of Biological Complexity
Virginia Commonwealth University
United States
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