Articles Related to periodontitis
Periodontal Maintenance Therapy and Generalized Aggressive Periodontitis: Brief Review of the Literature and Case Report
This case report presents an unusual variant of generalized aggressive periodontitis that was managed by nonsurgical therapy which included the use of a novel tooth gel. Also, a brief review of the literature is offered as context for this unusual clinical case. The patient, a 40-year old Caucasian female, presented with advanced bone loss involving all teeth, intense inflammation of the attached gingiva and little obvious supra- or subgingival biofilm and dental calculus. Presence of systemic disease, high levels of periodontal microbial pathogens and IL-1α and IL-1β polymorphisms were evaluated and all determined to be negative. Gingival biopsy resulted in a diagnosis of nonspecific inflammation. Treatment consisted of 2- and 3-month intervals for periodontal maintenance appointments and eventually the introduction of an activated edathamil-based tooth gel. Over the subsequent 4-years the patient’s periodontal status stabilized as manifested by no further loss of tooth supporting bone, a reduction in the percentage of periodontal pockets of 4-6 mm depth and a reduction in the percentage of sites exhibiting bleeding upon periodontal probing. The significance of this case report is to emphasize that, even in cases of severe generalized aggressive periodontitis, nonsurgical periodontal therapy can be effective. In addition, it appears that a novel tooth gel containing activated edathamil is effective at reducing gingival inflammation with a concomitant reduction in percent of sites that bleed on periodontal probing.
Porphyromonas gingivalis (P. gingivalis) is a primary etiologic agent of generalized aggressive and chronic forms of periodontitis. It releases toxins called ‘gingipains’.Gingipains, (Arginine-and Lysine-specific cysteine proteinases) are proteases that are critical virulence factors in progression of periodontitis and degradation of cytokines expressed during inflammation. HRgpA and RgpB (products of two distinct but related genes) induce vascular permeability by activation of the kallikrein/kinin pathway and activating the blood coagulation system which in turn induces gingival crevicular fluid production and progression of inflammation leading to alveolar bone loss.
Semiological Profile of Documented Apical Periodontitis: Case of the Clinic of Operative Dentistry and Endodontics (ODE) of the Department of Dentistry of Dakar
The prevalence of teeth carriers of periodontitis apical is universally high. Only the decontamination of the root canal system through cleaning, it’s shaping and its waterproof filling can ensure the eradication of infection at the level of the peri apex. The purpose of this prospective study was to establish the semiological profile of different types of periodontitis apical. The different characteristics used are subjective signs reported by the patient about the pain but also the clinical and radiographic features of each tooth with apical periodontitis.
Characterization and Antimicrobial Susceptibility of Aerococcus and Enterococcus Strains Isolated from Apical Periodontitis in Ouagadougou, Burkina Faso
Apical periodontitis is caused by polymicrobial infection. The causative bacteria are generally organized into biofilms that adhere to the canal walls, and may include facultative bacteria such as Aerococcus and Enterococcus, which are the causative agents of several endodontic infections and have a natural resistance to many antibiotics including penicillin.
Periodontitis is a multifactorial chronic inflammatory disease characterized by destruction of tooth supporting tissues. Repair of the periodontium and the regeneration of periodontal tissues remains a major goal in the treatment of periodontal disease and is an area still in need of major research attention.
Porphyromonas gingivalis is an anerobic, gram negative, bacterium which is a natural inhabitant of oral microbiome. Under unhealthy oral hygiene conditions the bacterium becomes highly destructive (photobiont) and leads to periodontitis (inflammation of periodontium).
Periodontal disease is a major oral health problem, in which specific species of bacteria play an important role in its progressing and severity. Because chronic periodontitis is believed to be asymptomatic in its initial stages, it has been suggested that individuals may be unaware of their clinical periodontal status [1-3] and underestimate what treatments are required, as judged by dental professionals .
The developments in the medicinal field led to demographic changes characterized by a growth in the elderly population. The proportion of patients with mobility limitations is higher in this population. Since the need for dental treatments does not skip any population group, a special facility had to be developed in order to solve problems of availability and accessibility.
Editorial Board Members Related to periodontitis
Department of Dental Basic Sciences
College of Dentistry
College of Dentistry