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Articles Related to pharmacological

Challenges in the Pharmacological Management of Non Hodgkin’s Lymphoma in Children in the Maintenance Phase of Therapy at Kenyatta National Hospital

Non Hodgkin’s lymphoma is an extremely chemo sensitive with a five year event free survival of greater than 90% in developed countries and a one year survival rate of 40-50% in developing countries.
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An Introduction to the Approaches of Novel Drug Delivery Systems for Acquired Immune Deficiency Syndrome (AIDS)

The currently available anti HIV agents have several drawbacks such as short half life, low bioavailability, poor CNS penetration and retention, hepatic first pass metabolism, undesirable side effects and frequent dosing regimen.
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Researches on the Pharmacological Effects of Eicosapentaenoic Acid

Fish oils are the most common source of omega-3 polyunsaturated fatty acids (n-3 PUFAs), mainly eicosapentaenoic acid (EPA). It has been pointed out protective effects and beneficial effects of EPA on body weight reduction, heart health, blood lipid profile, cardiovascular diseases and other diseases. Based on its biological activities, EPA may be developed to a complementary and alternative medicine through further research. In this paper, the pharmacological effects of EPA were summarized by reviewing the recent related literatures.
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Review on Pharmacological Activities of the Peptides from Scorpion Buthus Martensii Karsch

In China, the scorpion Buthus martensii Karsch is used as functional food and medicinal materials. The scorpion, scorpion venoms and their extracts are effective in treating a variety of nervous system diseases such as epilepsy, apoplexy pains and facial paralysis.
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Review on Transdermal Drug Delivery Systems

Recently, transdermal drug delivery system (TDDS) has become a more and more important approach to administering drugs. Based on its advantages, which are not achievable by other modes of administration, many researchers are dedicated to the study of it, and have made great progress. Although the skin offers a painless interface for systemic drug delivery, it also presents limitations which are mainly caused by the stratum corneum.
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Wet Granulation to Overcome Liquisolid Technique Issues of Poor Flowability and Compactibility: A Study to Enhance Glibenclamide Dissolution

The aim of this study is to apply wet granulation on liquisolid powders to overcome issues of poor powder flowability and compressibility especially with using high viscosity liquid vehicles. Different liquisolid formulations were made using three excipients where the effect of each excipient used in the dissolution of the model hydrophobic drug (Glibenclamide) was evaluated. The Glibenclamide tablets were formulated using PEG 400, Synperonic PE/L44 and Cremophor ELP, at a 10 %w/w in liquid vehicle drug concentration. The carrier (Avicel®PH102) was used followed by colloidal silicon dioxide (coating material) that converted the wet mixture into dry powder. Potato starch, 5%w/w, as a disintegrant was mixed with the mixture manually for 10 minutes and was finalized by adding 0.75% of magnesium stearate as a lubricant.
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Perspectives and Potential Applications of Ruthenium-Based Nanocarriers for Cancer Therapy

Cancer is a highly heterogeneous disease characterised by continuous uncontrolled growth and expansion of abnormal cells. In general, in tumor cells the signalling pathways regulating cellular processes, as cell growth and division and cell to cellcommunication result strongly altered.
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Biocompatible Polymers and Processing Techniques in Drug Delivery and Tissue Engineering

In recent years many progress has been achieved in the biomedical and biopharmaceutical fields particularly in drug delivery and regenerative medicine. This has been possible thanks to the increased expertise in polymers chemistry as well as the advent of innovative techniques of materials manipulation that have lead to the production of new “smart” polymeric devices with peculiar propertiesable to selectively reach almost all areas of the human body, in the case of drug delivery systems, or to reduce the chemical-physical gap between human tissues and synthetic devices, in the case of tissue engineering.
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Editorial Board Members Related to pharmacological

Robert Kinobe

Senior Lecturer
Physiology and Pharmacology
School of Veterinary and Biomedical Sciences
Australia

KRZYSZTOF KOSTRO

Professor
Department of Epizootiology and Clinic of Infectious Diseases
Lublin University
Poland

Alok Dabi

Assistant Professor
Department of Neurology and Neurosurgery
University of Texas Medical Branch (UTMB)
United States

MENG-YANG ZHU

Associate Professor
Department of Pharmacology
Quillen College of Medicine
East Tennessee State University
United States

Jean-François Desaphy

Associate Professor
Department of Pharmacy & Drug Sciences
University of Bari
Italy

James David Adams

Associate Professor
Department of Pharmacology and Pharmaceutical Sciences
University of Southern California
United States

KONSTANTINOS PAPAMICHAEL

Gastroenterologist
Medical School
University of Athens
Greece

Richard Lobo

Associate Professor
Department of Pharmacognosy
Manipal College of Pharmaceutical Sciences
India

Shi J. Liu

Professor
Department of Pharmaceutical Sciences
University of Arkansas for Medical Sciences
United States

Yu Huang

Professor
School of Biomedical Sciences
Chinese University of Hong Kong
Hong Kong
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