Articles Related to polymer

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Patients with Philadelphia-negative myeloproliferative neoplasms (PN-MPN) are at a higher risk for venous thrombosis. Thromboelastometry may prove efficient to evaluate the patient’s thrombotic risk. In this study, based on data from 114 patients with PN-MPN from a single center in Greece, hemostatic profile was assessed with routine coagulation tests, Rotational Thromboelastometry (ROTEM® ), and Platelet Function Analyzer (PFA)-100 and correlated with clinical, laboratory, treatment characteristics, gene mutations and polymorphisms of poly (ADP-ribose) polymerase-1 (PARP-1)

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The unlawful and uncontrolled disposal of waste tyres is greatly disturbing in terms of the environmental concerns and the economic misfortune. In combating this menace, there is growing interest in the application of efficient and environmental-friendly alternatives to the traditional recycling methods for waste tyres. Pyrolysis can be considered as an appropriate non-conventional method for complex materials such as tyres. Several works have been made to improve pyrolysis process towards higher yield and quality of biofuels and greater energy efficiency. This study considers Reverse Polymerization, a microwave-assisted pyrolysis process to extract complete yield and higher quality of valuable products, while avoiding toxic emissions into the environment. The feasibility of such innovative recycling process in Sub-Sahara Africa is essential in order to convince concerned authorities to buy into such advanced technologies with great benefits. The investment analysis and economic performance indicators from the study demonstrated that the operation of such proposed recycling system in the continent is economically feasible. However, the operation of such facility under the present market conditions might highly be challenged by high investment risk as the project is highly capital intensive.

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Intra- or inter-chain dipole–dipole interactions between opposite charges cause collapse of the structure in polyampholyte hydrogels formed by using ionic monomers with different charges. Furthermore, these interactions are unavoidable as in the case of clamped polymer chains.

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Sickle cell disease is a prevalent and severe monogenic disorder resulting from a homozygous missense mutation in the β-globin gene that leads to polymerization of hemoglobin S. Clinical manifestations of the disease can be critical with considerable morbidity and mortality. One treatment option for the disease is bone marrow transplantation. However this method is restricted to the patients with an appropriately matched donor. Gene therapy by either gene insertion or gene editing, utilizing patient’s own cell is a primary therapeutic option to cure sickle cell disease. However, very less clinical trials have been performed with genetic therapy for treating Sickle cell disease (SCD). Since a couple of decades significant progress has been made in the area of gene therapy for treating monogenic hemoglobin disorders. Numerous therapies are currently in clinical trial stages or in preclinical stages. The safety and efficacy of gene therapy has been greatly improved with the initial use of γ-retrovirus vectors, followed by next-generation lentivirus vectors, and latest gene editing techniques. Although the clinical interpretation of gene therapy has been successful, it involves some limitations including complex cellular abnormalities, inadequate transgene expression, and challenges in achieving effective and persistent inhibition of polymerization of hemoglobin S. This review intends to discuss gene therapy strategies specific to Sickle cell disease, present state of the field, and current status of the gene therapy clinical trials.

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Packaging material should meet many requirements for safe preservation of food and extend shelf life. Utilization of nanoparticles to prepare active packaging films has been widely investigated. This review deals with food packaging films modified with nano titania to enhance mechanical, barrier and antibacterial properties of the packages.

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In recent years, increasing evidence has pointed to the potential role of fibrinolysis in the pathogenesis of MS. Based on hypotheses describing the aggressive autoimmune responses observed in MS patients, a result of impaired between (t-PA and PA1-1) which are a key molecules in both fibrinolysis and extracellular proteolysis. The present study was done to investigate the therapeutic potential of polymerase enzyme in modulating the changes occurred between levels of Tissue- type plasminogen activator (t-PA) and its inhibitor (PAI-1) in patients with multiple sclerosis. A pilot study was carried out on a total of twenty-one patients (17 females, 4 males; aged 22-46 years) with demyelination suggestive of MS and clinically silent T2 brain lesions on magnetic resonance imaging (MRI).

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NanotechnologyAbstractIntroductionIn order to successfully reduce the weight of a helical spring it is possible to optimize the material parameters or to use alternative advanced materials instead of conventional engineering ones. Springs are used for vibration damping in mechanical systems and are generally made of steel. As an alternative to material of steel springs in the scope of the study, mechanical behaviors of fiber reinforced polymer (FRP) composite helical springs have been investigated. The FRP composite material has made it possible to reduce the weight of helical spring without any reduction on load carrying capacity. Due to increasing competition and innovation in recent decades, vehicle industries show interest in replacing conventional steel spring with FRP composite helical spring which has advantages such as higher strength to weight ratio, higher stiffness, high impact energy absorption and lesser stresses. The study gives the brief look on the suitability of FRP composite helical springs on related mechanical systems. The objective of the present work is evaluation of the design, analysis and fabrication of FRP composite helical springs.

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It is a one pot synthesis of hybrid bionanocomposite comprising of inorganic magnetite with stabiliser biopolymer pectin and alginate in co-precipitation method using sodium hydroxide and ammonium hydroxide as precipitating agents.

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Camelpox is routinely diagnosed based on clinical signs, pathological findings and cellular and molecular assays.

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Haemoglobinopathies are inherited disorders of haemoglobin synthesis that are responsible for significant morbidity and mortality all over the world.

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Several studies have suggested that Insertion/Deletion polymorphism of ApoB gene is associated with obesity, dyslipidemia, diabetes and coronary heart disease (CHD).

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The currently available anti HIV agents have several drawbacks such as short half life, low bioavailability, poor CNS penetration and retention, hepatic first pass metabolism, undesirable side effects and frequent dosing regimen.

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Congenital dyserythropoietic anemia type III (CDA III) can be caused by mutation in KIF23. CDA III differs from CDA I and II in the sense that secondary hemochromatosis has not been reported. However, we have observed elevated serum ferritin in a CDA III family.

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A translucent UV protecting poly (methyl methacrylate) (PMMA)/TiO2 nanocomposite has been fabricated using anatase TiO2 nanoparticles by solution method. The myristic acid capped titania nanoparticles were synthesized via a simple sol-gel method, involving hydrolysis of titanium tetra isopropoxide (TTIP).

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The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.

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