Articles Related to prophylactic
The Efficacy and Safety of Prophylactic Fluconazole Prevent Invasive Fungal Infection in Preterm Very Low Birth Weight Infants: An Update Meta-analysis
We identified 8 eligible trials that enrolled 1392 infants. There was significant effect of prophylactic fluconazole on fungal colonization (RR, 0.31, 95%C1:-0.24 to 0.41; P<0.00001). Effect of prophylactic fluconazole on IFI in VLBW infants: RR: 0.42(95%CI 0.23 to 0.76; P=0.004.). However, prophylactic fluconazole did not reduce mortality in VLBW infants (RR 0.76, 95% CI 0.58 to 1.01; P = 0.06). Studies did not report significant adverse reactions.
Effects of Oxytocin and Carbetocin on Haemostatic Variables in Pregnant Women after Cesarean Section
Uterine atony is the first cause of haemorrhage at delivery. To prevent post partum major bleeding uterotonic prophylactic drugs are commonly used after caesarean section. Few studies showed an haemostatic activation after oxytocin infusion while no data are available on carbetocin.
Pharmacy Compounding Quality Control and Pharmaceutical Development Strategies for Seventeen alpha Hydroxyprogesterone Caproate in Prevention of Preterm Delivery
Seventeen alpha hydroxyprogesterone caproate (17-OHPC) is the only FDA-approved drug labeled for prevention of preterm delivery. This drug is also available as a compounded product from licensed compounding pharmacies. This article reviews the FDA approval history and pharmacy compounding quality control data of 17-OHPC, as well as briefly discusses possible future pharmaceutical development strategies for 17-OHPC.
Editorial Board Members Related to prophylactic
Parichat Phumkhachorn
Assistant Professor
Department of Biological Science
Ubon Ratchathani University
Thailand
Department of Biological Science
Ubon Ratchathani University
Thailand
MICHAEL P. SHERMAN
Professor Emeritus
Department of Child Health
Division of Neonatology
University of California-Davis School of Medicine
United States
Department of Child Health
Division of Neonatology
University of California-Davis School of Medicine
United States