Articles Related to shock

Background and Objective: Septic shock remains an impatient cause of morbidity and mortality. Early restitution of the circulation improve tissue oxygen delivery and increase survival. This study is a prospective randomized single center study its main objective is to investigate the therapeutic value of hypertonic saline in patients with septic shock. Methods: Fifty-two critically ill patients admitted with septic shock divided into two groups, the first group received isotonic saline (control group) starch, while the second received hypertonic saline 5%.

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The aim of this study is to describe clinical variables and comorbidities in patients with shock, at arrival to the emergency department, and evaluate the diagnostic validity for different shock etiologies. This was a retrospective cohort study with tertiary analysis of data previously published in two other studies. The study population was all patients with shock, arriving to the emergency department at Odense University Hospital between 2000 and 2011. Shock was defined as systolic blood pressure ≤100mmHg and one or more organ failures. Patients were grouped according to discharge diagnoses and this method was manually validated through patient records. The diagnostic value of 26 clinical variables and 10 comorbidities were described and tested.

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We are reporting an infant who was born by emergency cesarean section following failed vaginal delivery. This infant was noted to be in hypovolemic shock soon after birth. He developed large subgaleal hemorrhage within 6 hours after birth with associated diffuse intravascular coagulopathy and hypoxic-ischemic encephalopathy. He required multiple transfusions of packed red blood cell, platelets transfusion, fresh frozen plasma transfusions, and a cryoprecipitate. The infant was on body cooling therapy for hypoxic ischemic encephalopathy for three days. His neurological exam at the time of discharge was unremarkable. At the time of discharge, an infant is enrolled in an early intervention program with a multi-disciplinary follow-up scheduled.

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Patients admitted to the emergency room or intensive care units (ICUs) need real-time monitoring of body oxygen balance. As of today, the availability of monitoring devices that provide real-time data on tissue level of oxygen homeostasis is very limited. The involvement of mitochondrial dysfunction in many pathological states such as stroke, sepsis or heart failure is calling for a real-time evaluation of this intracellular organelle. In order to avoid the deterioration of the most vital organs in the body (brain and heart), we are proposing to monitor a less vital organ, such as the urethral wall, that serves as an early warning signal for the deterioration of body oxygen balance.

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Spasticity is defined as ‘a disorder of sensorimotor control, resulting from an upper motor neuron (UMN) lesion, presenting as intermittent or sustained involuntary activation of muscles’. It is characterized by increased involuntary velocity-dependent tonic stretch reflexes (muscle tone) with exaggerated tendon jerks, resulting from hyper-excitability of the stretch reflex. In the recent years,a range of non-pharmacological interventions has been used to manage spasticity. Among the novel of all therapies, extracorporeal shock wave therapy (ESWT) is attractive for many researchers since the noninvasive, easy application after well training and afety property. Moreover, the evidences of regeneration of musculoskeletal tissues made ESWT more interesting than other novel therapies.This article will show the evidences, practical clinical use and precaution to guide treating for the clinicians in the novel therapy of ESWT for spasticity. The review of the scientific evidences including methodology components and main results of ESWT treatment on upper limb and lower limb muscles affected by post-stroke spasticity are demonstrated. However, reducing spasticity alone without addressing the negative components of the upper motor neuron syndrome will limit meaningful recovery. A combination of rehabilitation techniques is needed to facilitate functional improvements.

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Hydrogen gas has been used widely in the industrial aspect, especially as clean energy. On one hand, it reduces the dependency on fossil fuels; on the other hand, it solves the environmental polluting issue and also reduces the greenhouse gases emitted to the environment. Producing hydrogen by chemical and physical methods require higher fee and investment. Producing hydrogen from renewable biomass, especially agricultural waste such as straws, can produce with low cost and decrease the amount of agricultural waste and pollutions. This article introduces the result of the beginning research to produce hydrogen gas from straw using biotechnology.

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Salmonella-associated diarrhea is a common cause of community-acquired gastroenteritis. Some species of salmonella are associated with invasive diseases like meningitis, endocarditis and septicemia.

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This case report describes the diagnosis and management of a large mesenteric cyst in a 55 year old lady who presented with abdominal distension & with mass in the left upper quadrant. Mesenteric cysts are rare, benign, abdominal tumors to which <1000 cases have been reported in the literature.

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There are approximately 300,000 out-of-hospital cardiac arrests per year with less than 10% of those surviving. More than half of survivors suffer permanent neurologic deficits. Therapeutic hypothermia has proven effective at thwarting neurologic damage occurring in the 16-hour window following return of spontaneous circulation (ROSC). Despite recommendations by the American Heart Association (AHA), many cardiologists have been slow to implement therapeutic hypothermia. While many trials have discussed the relevance of initial rhythm and delay of cooling, there has been limited discussion of the efficacy of therapeutic hypothermia in the presence of extended pulselessness.

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