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Articles Related to skin

Case Report: Pyoderma Gangrenosum in IBD Treated with Tofacitinib

Pyoderma gangrenosum is a rare ulcerating skin disease often presenting as an extra intestinal manifestation of IBD and is difficult to manage. Treatment options for pyoderma gangrenosum include steroids, calcineurin inhibitors and anti TNF agents. Here in, we report a case of recurrent Pyoderma gangrenosum with Ulcerative Colitis that was successfully managed with Tofacintib, a JAK inhibitor
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Falsely Low HbA1c Unmasking a Latent HbE Defec

The current case report illustrates role of vigilant laboratory services that helped in unmasking asymptomatic HbE variant in a middle aged known diabetic woman who came as an outdoor patient and on subsequent HbA1c testing was found to have lower value -2.9 %. It triggered extensive workup after looking for common causes and an electrophoresis of Hemoglobin revealed HbE variant.
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Malignant Scalp Tumors: Retrospective Analysis of 1000 Patients.

Background: Limited data on large cohort of patients with malignant tumors of the scalp are available in the literature. The aim of this study was to review a large cohort of patients with malignant scalp tumors to determine epidemilogy, tumor characteristics of this region and treatment. Materials and Method: A retrospective review of patients with malignant scalp tumors diagnosed histopathologically between 2005 and 2021 was performed. Demographic features and tumor characteristics were analyzed. Results: A total of 1080 patients (M: F 3,5:1) were treated and followed up for a mean period of 42 months (12-120 months). Age at diagnosis ranged from 12 to 98 years. Most malignant scalp tumors (95,1%) occurred in those 50 years or older and in bald patients (87%). Basal cell carcinomas (59,2%), squamous cell carcinomas (32,2%) and melanomas were the most common histologic types. Incidence was highest on the frontal of temporal region (66,1%). Recurrence was frequently in squamous and basal cell carcinomas but uncommon in melanoma. Conclusions: Tumors of the scalp accounted about 8,01 % of all skin cancers. Tend to be basal and squamous cell carcinomas, many of which occur in the temporal and frontal region of bald men. The outlook for patients with scalp tumor is positive, although we suggest excision margins of at least 3-4 mm and continued clinical vigilance is warranted given their higher recurrence rates.
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Erythematous, Hyperkeratotic Papule on the Left Distal Dorsal Aspect of the Middle Finger

Dermatofibroma (DF) is a common benign fibrosing lesion that can be found on any surface of the body, most often in the lower extremities. Dermatofibroma that arises on the digits, as in our present case, may be confused with other clinical entities or even malignant tumors, leading to unnecessarily aggressive treatment. To ensure proper diagnosis and treatment, dermatofibroma should be considered in the differential diagnosis of digital papules.
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Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Twin Sisters after Ibuprofen Administration. New Insights in Pathogenesis and Literature Review

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are closely-related, severe, acute life-threatening, drug-induced skin and mucosal disorders with a high mortality rate or long-term damages. These medical conditions are considered a delayed, typeIV hypersensitivity reaction and can be triggered by drugs, infections and malignancies.
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Latent Fingerprint on Human Skin: A Silent Diagnosis

Fingerprints are one of the most valuable evidence due to their uniqueness.
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Clinical Study on the Efficacy of Vipadikahara Grita Taila on the Treatment of Vipadika Skin Disease

Ayurveda has discussed all skin diseases under the name of Kushtha, and in other words it can be known as “Ayurveda Dermatology”. Eighteen types of these skin diseases are mainly divided into seven types of Maha Kushtha and eleven types of Kshudra Kushtha. Vipadika skin disease is diagnosed with the help of critical and analytical study of the literature in original Sanskrit texts and later clinical trial was carried out. In the present study, efficacy of Vipadikahara grita taila was assessed against Vipadika skin disease.
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Hemophagocytic Lymphohistiocytosis Secondary to Dermatopathic Lymphadenitis

Dermatopathic lymphadenitis (DL) is considered a benign disease, the symptoms of which can be relieved with only anti–histamine. It can be confused with lymphoma. Here, we report a case of DL, which resulted in hemophagocytic lymphohistiocytosis (HLH). After adequate treatment, remission was obtained at first; however, recurrence with liver failure occurred six months later, which quickly resulted in death. This particular case has not been reported elsewhere. It reminds us that even benign dermatological problems can cause life–threatening syndromes, such as, in this case, HLH. The risk needs to be taken seriously in patients presenting with fever, skin problems, and lymphadenopathy.
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Impact of Inverted Interrupted Skin Suturing Versus Continous Suturing in Episiotomy on Postpartum Pain in Primigravida

Episiotomy is an incision that is made in perineum at the end of part of second stage of delivery. There are Long term sequels of episiotomy repair. A considerable number of ladies complains from perineal pain and up to twenty percent have long term complications e.g., dyspareunia [1]. The best method for repairing episiotomy is the method that isnot time consuming and lesser materials and causes lesser pain in the immediate and long term periods.
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An Infant with Liver, Kidney, Skin and Musculoskeletal Abnormalities

A 21 day-old boy infant was admitted to pediatric intensive care unit with hypotonia, jaundice and abdominal distention. He was born at 37th week of gestation from first cousin Saudi parents via cesarian section with a birth weight of 2200 g. Physical examination revealed the weight, the length was and the head circumference were <3rd percentile. Dysmorphic features included flattened nasal bridge, high arched palate, lax skin and micrognathia. There were generalized hypotonia, hepatomegaly, abdominal distention and multiple contractures such as radial deviation of the wrist joint (Figure 1).
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Dual Fall, One Before and other after A High Voltage Electric Injury-Case Report

Electric injury by high voltage current is an event that has a very high rate of morbidity as well as mortality. Arcing is unique to high voltage electric injury where current is transferred between two points not in contact.
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Serum Haptoglobin Responses following Rumenotomy in the Sahel Goat

Fifteen Sahel goats were randomly allocated into three groups A, B and C to evaluate Serum Haptoglobin (Hp) profiles following rumenotomy as markers of surgical stress using Quantitative ELISA.
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An Effective Treatment Regimen for Warts in Cattle

The study was aimed to evaluate the potency and for advocation of a homeopathic drug regimen against warts. Sixty six cattle of variable age presented with warts on skin, eyelids, ears, muzzle, udder and external genitals.
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Nonparametric estimation of cumulative cause specific reversed hazard rates under masked causes of failure

In the analysis of competing risks data, it is common that the exact cause of failure for certain study subjects is missing. This problem of missing failure type may be due to inadequacy in the diagnostic mechanism or reluctance to report the exact cause of failure.
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Parenteral Nutrition in the Newborn: Associated Disorders and Nutritional Aspects

Severe prematurity at birth is an indicator of additional attention for the multidisciplinary team, since the newborn in this condition did not have the opportunity to develop organic systems under ideal conditions (intrauterine). Several factors may induce premature birth, malformation of organs or metabolic disruptions, however, additional attention has been given to inborn errors of metabolism (IEM) and deficiency/excess of key nutrients.
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Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS

The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.
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Editorial Board Members Related to skin

MATEJ TRAPECAR

Assistant Professor
National Forensic Laboratory
Slovenia

Richard Simman

Clinical Associate Professor
Department of Surgery
Wright State University Boonshoft School
United States

SAJA H. HAMED

Associate Professor
Department of Pharmaceutics and Pharmaceutical Technology
Hashemite University
Jordan

AMIR A. BAJOGHLI

Clinical Associate Professor
Department of Dermatology
Virginia Commonwealth University Inova Medical Campus
United States

Khalid M. El-Say

Associate professor
Department of Pharmaceutics and Industrial pharmacy
King Abdulaziz University
Saudi Arabia

Giacomo Zaccone

Professor
Department of Biomedical Sciences Dentistry, Morphological and Functional Images
University of Messina
Italy

Marcelo L. Rodriguez-Puebla

Associate Professor
Department of Molecular Biomedical Sciences
North Carolina State University
United States

IOANNIS D. BASSUKAS

Professor
Dermatology
School of Medicine
University of Ioannina
Greece

Muzzafar Zaman

Assistant professor
Department of Surgery
Maharishi Markandeshwer Institute of Medical Sciences and Research
India

NORMA RANGEL

Professor Research
Division of Graduate Studies and Research
Institute of Technology Aguascalientes (ITA)
Technological Institute of Aguascalientes (ITA)
Mexico
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