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Articles Related to tissue

DNA Polymerase as Therapeutic Intervention for Treating Patients with Multiple Sclerosis

In recent years, increasing evidence has pointed to the potential role of fibrinolysis in the pathogenesis of MS. Based on hypotheses describing the aggressive autoimmune responses observed in MS patients, a result of impaired between (t-PA and PA1-1) which are a key molecules in both fibrinolysis and extracellular proteolysis. The present study was done to investigate the therapeutic potential of polymerase enzyme in modulating the changes occurred between levels of Tissue- type plasminogen activator (t-PA) and its inhibitor (PAI-1) in patients with multiple sclerosis. A pilot study was carried out on a total of twenty-one patients (17 females, 4 males; aged 22-46 years) with demyelination suggestive of MS and clinically silent T2 brain lesions on magnetic resonance imaging (MRI).
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Co-culture of Buccal Mucosal Epithelial Cells Downregulate CTGF Expression in Urethral Stricture Fibroblasts

Buccal mucosal urethroplasty has revolutionized the surgical management of urethral strictures but the success of the procedure has been variable in different series. We have attempted to understand the interplay between buccal mucosal epithelial cells (BME) and the fibroblasts at the molecular level using connective tissue growth factor (CTGF) as a marker so that translation of this information would help in better urethroplasty outcomes. Materials and Methods: The morphological and functional characteristics of normal urethral fibroblasts (NUF) and urethral stricture fibroblasts (UStF) with and without co-culture with BMEs are compared. The intracellular and extracellular level of CTGF expression in the UStF co-cultured with BMEs was analyzed by using molecular biology methods.
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Potentials, Limitations and Future Directions of MR Contrast Media in Ablation Therapies

ImagingIntroductionMR contrast media have become an indispensable part of magnetic resonance (MR) imaging, but their roles in ablation therapies are still controversial. The interactions between physical/biological properties of MR contrast media (Longitudinal=T1, transverse=T2 and susceptibility=T2* relaxation times) and diseased tissues (perfusion, edema, hemorrhage and coagulative necrosis) play important roles in differentiating pathologic and ablated tissues.
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Breast Cancer Detection by Determination of Optical Properties of Non-Malignant and Malignant Breast Tissues

Breast cancer being one of the most frequent form of cancer, is the leading cause of cancer deaths in women worldwide. Early detection can greatly improve a woman`s chances for survival. In this paper we introduce an economic and accurate optical system for breast cancer detection.
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Improvements to In Vitro Culture Media for Use in Bovine IVF

In assisted reproduction of cattle the design and preparation of in vitro culture media has been instrumental in supporting the development of bovine oocytes and embryos. In vitro production (IVP) involves three main sequential steps: oocyte aspiration and in vitro maturation (IVM); in vitro fertilization (IVF); and in vitro culture (IVC) of early pre-implantation embryos.
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Prone Airway Management in Patients with Pressure Ulcers

Pressure ulcers are a critical but manageable complication commonly seen in bed-bound patients. Utilizing the Wound Bed Preparation (WBP) model, it is often necessary to perform surgical debridement in prone position for patients with stage III or IV sacral pressure ulcers to avoid infection and further complications.
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Mitochondrial Actions for Fat Browning and Energy Expenditure in White Adipose Tissue

White adipose tissue (WAT) is an endocrine organ with crucial role in the development of obesity and related diseases. White adipocytes have less mitochondria than brown adipocytes; nevertheless, there is an increasing body of evidence showing that mitochondrial parameters play a relevant role in WAT physiology, such as proliferation, differentiation and triacylglycerol storage levels.
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Sudden Death Due to Sarcoma: An Unusual Case and Literature Review

Sudden death has varied causes, and autopsy is usually required to determine cause of death. Sarcoma involvement is very infrequent, and detailed pathological evaluation is needed for correct diagnosis.
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Mesenchymal Stem Cells from Different Tissues: Immune Status and Activity

Mesenchymal stem cells (MSCs) have been found in almost all tissues and due to their regenerative properties represent promising tools in cell-based therapy. Role of MSCs in tissue repair is strongly governed by their interplay with immune cells and regulating factors.
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The Role of Nutrition in Fighting Free Radicals

This paper aims to review in literature the main mechanisms of oxidative stress, pointing out the major formed metabolites, the mechanisms of cell damage and major antioxidants. Oxygen is essential to human life. The formation of free radicals (FR) is closely related to oxygen consumption, a mechanism that occurs with an incomplete reduction of this molecule.
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Combating Childhood Obesity with an Integrated School Curriculum

The prevalence of overweight and obesity among US adults is well-documented and lifestyle intervention remains the foundation for all overweight and obesity treatment interventions, even when bariatric surgery is offered. Unfortunately, lifestyle intervention, though clearly a vital part of any obesity treatment, including bariatric surgery, has not been found to be as effective in achieving health benefits as hoped for.
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Warfarin-Induced Tissue Necrosis (WITN): Case Report and Literature Review, A Proposed Name Change

Warfarin is the most frequently prescribed oral anticoagulant in the United States. Its indications range from treatment of deep venous thrombosis and pulmonary emboli to the prophylaxis and treatment of thromboembolic conditions associated with atrial fibrillation and cardiac valve replacement. While bleeding is the most commonly encountered complication warfarin induced skin necrosis (WISN) can be a rare complication. Extensive skin and deeper tissue necrosis may be encountered requiring multiple surgical debridement and reconstructive procedures along with the medical management.
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A Case Report of Atrial Myxoma presenting with Cardioembolic Stroke and treated with Intravenous Thrombolytic Therapy

Cardiac myxomas are a potential source of emboli to the brain and elsewhere in the vascular tree. Myxomas are the most common benign primary cardiac tumor in adults. The commonest location of cardiac myxomas is in the left atrium followed by the right atrium and the remainder develops in the ventricles and rarely in the heart valves.
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Malignant Fibrous Histiocytoma Accompanying Hemorrhage in the Pleural Cavity

Malignant fibrous histiocytoma is a type of soft tissue tumor that frequently occurs in the limbs, trunk, retroperitoneum, etc. We herein report a case of MFH occurring in the thoracic wall, which was accompanied by hemorrhage in the pleural cavity. A 79-year-old male transferred to our hospital for a detailed examination of a chest wall tumor in his right back. The tumor was diagnosed as pleomorphic malignant fibrous histiocytoma (MFH) by an incisional biopsy.
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Unusual Variant of Guillain-Barré Syndrome Following Hepato-biliary Surgery — A Rare Case Report

Guillain-barré syndrome (G.B. Syndrome) is an acute inflammatory poly-radiculoneuropathy characterized by weakness and areflexia typically following viral infection, vaccination, and rarely surgery. Acute Inflammatory Demyelinating Poly-radiculoneuropathy is the most common subtype of G.B. Syndrome. Although post-operative G.B. syndrome is a rare entity, there are few case reports of G.B. syndrome after gastric surgery. But there have been no reported case scenarios of atypical variety of this neurologic entity following hepato billiary surgery. Hence our objective is to put forward this message to the readers.
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Editorial Board Members Related to tissue

Jian Yang

Associate Professor
Department of Bioengineering
Pennsylvania State University
United States

Dagmara McGuinness

Research Associate
College of Medical
Veterinary & Life Sciences
Institute of Cancer Sciences
Western Infirmary Glasgow
Scotland

Hongxia Hao

Lecturer
Department of Chemistry
University of Toronto
Canada

MOHAMED FARAG AYAD

Professor
Department of Oral and Maxillofacial Rehabilitation
King Abdulaziz University
Saudi Arabia

SANTAMARIA RITA

Associate Professor
Department of Pharmacy
University of Naples Federico II
Italy

Syed Ameer Haider Jafri

Assistant professor
Department of pedodontic and preventive dentistry
King Salman North West Armed Force Hospital
Saudi Arabia

Qingsong Ye

Associate Professor
Department of Orthodontics
James Cook University
Australia

PATRICIA A. KRUK

Professor
Department of Obstetrics and Gynecology
USF Morsani College of Medicine
University of South Florida
United States

Ren-Ke Li

Professor
Laboratory Medicine and Pathobiology
University of Toronto
Canada

Gianluca Vadala

Orthopaedic Surgeon
Department of Orthopaedic and Trauma Surgery
Campus Bio-Medico University of Rome
Italy
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