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Articles Related to toxicity

Ventricular Arrhythmia Due to Yellow Phosphorus Poisoning

Ratol paste (Yellow Phosphorus) is a local and systemic toxin affecting almost all the organs of the body especially liver, kidney, brain and heart. There is no specific antidote for yellow phosphorus poisoning. Heart is one of the many organs affected by the YP. However cardiac toxicity following acute ingestion of YP has been reported rarely.
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A Non-Contact Passive Approach for the Effective Collection of Target Explosive Volatiles for Canine Training Aid Development

The use of real explosive materials for canine training involves inherent dangers, toxicity risks exposure, and often limited availability of the training material all of which may affect the reliable training of canine teams. For this reason, the development of a training aid suitable for daily operations is beneficial to provide safe and effective explosive detection training that can provide for enhanced detection capabilities.
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A Review on Nanoprobes for Sensing, Imaging and Disease Detection

This review focuses on imaging, visualization and detection of diseases using nanoprobes. Several currently available nanoprobes such as fluorescent nanoprobes, upconversion nanoparticle probes, supermagnetic iron oxide nanoprobes, and polymer- and liposome based nanoprobes are discussed.
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Lead (Pb) Toxicity Trigger Schizophrenia in Battery Workers of North Region of India

Total production of Pb acid batteries in India is about 8 million per year and nearly 10,000 Kg of Pb is consumed in the production of batteries.
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Anti-GnRH Receptor Monoclonal Antibodies, First-In-Class GnRH Analog

A monoclonal antibody (Mab) designated as GHR106 was generated against the extracellular domain (N1-29 synthetic peptide) of human gonadotropin releasing hormone (GnRH) receptor. It is a first-in-class GnRH analog and can serve as a drug candidate for potential applications in the treatment of human cancers and/or fertility regulations.
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Street Drug, an Inotrope in Heart Failure?

Methamphetamine is one of the most commonly abused illegal stimulants and causes the release of dopamine, norepinephrine and serotonin. These neurotransmitters trigger vasospasm, causing persistent tachycardia, hypertension, and direct myocardial toxicity. Moderate usage of methamphetamine can increase cardiac output and myocardial contractility. However, larger doses can cause depression of the myocardium.
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Amyloid beta precursor protein: forgotten facts of the most studied protein in the 21st Century*

The amyloid precursor protein (APP) is mainly known for being the precursor of the ß-amyloid peptide, which accumulates in plaques found in the brain of Alzheimer’s disease patients. Expression in different tissues and the degree of sequence identity among mammals indicate an essential and non-tissue specific physiological function.
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Targeted Approach for Prostate Cancer Treatment: Synthesis and Characterization of Docetaxel-Loaded Perfluorocarbon Nanodroplets

The purpose of this study is to synthesize and characterize nanodroplets, loaded with docetaxel for treatment of prostate cancer under MR-guided focused ultrasound. Water insoluble docetaxel encapsulated in nanodroplets is expected to be delivered into tumors with greater efficiency while minimizing drug related systemic toxicities when used in combination with focused ultrasound. The sequence of our studies toward development and characterization of docetaxel-loaded nanodroplets is as follows. First, we developed methods for synthesis of ultrasound-responsive, docetaxel-loaded nanodroplets (Doc-nd) by a solid dispersion technique. Secondly, we characterized Doc-nd by its morphology and size distributions using a dynamic light scattering (DLS) method.
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Perspectives and Potential Applications of Ruthenium-Based Nanocarriers for Cancer Therapy

Cancer is a highly heterogeneous disease characterised by continuous uncontrolled growth and expansion of abnormal cells. In general, in tumor cells the signalling pathways regulating cellular processes, as cell growth and division and cell to cellcommunication result strongly altered.
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Thoroughbred Race Horses Management: A Key Role of the Veterinarian

The veterinarian must confront many situations when working with thoroughbred horses in which he must solve and make decisions that lead to balance between the animal and trainer / owner of the horse, the above should be resolved in an ethical and professional manner.
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Editorial Board Members Related to toxicity

Bidyut Roy

Professor
Human Genetics Unit
Indian Statistical Institute
India

PAULA M. CHILTON

Assistant Professor
Department of Microbiology & Immunology
University of Louisville
United States

Vincenzo Cuomo

Professor
Department of Pharmacology
University of Rome
Italy

Remigius U Agu

Associate Professor
Faculty of Pharmaceutical Sciences
University of Kentucky
United States

Louis-Ferdinand

Professor
Department of Pharmaceutical Sciences
Wayne State University
United States

Tibor Harkany

Professor
Department of Medical Biochemistry & Biophysics
Karolinska Institute
Sweden

David J. MacEwan

Professor
Department of Molecular & Clinical Pharmacology
Institute of Translational Medicine
University of Liverpool
United Kingdom

MENG-YANG ZHU

Associate Professor
Department of Pharmacology
Quillen College of Medicine
East Tennessee State University
United States

Stan W. Casteel

Professor
Department of Veterinary Pathobiology
University of Missouri
United States

Cemil Yesilsoy

Associate Professor
Department of Endodontology
Temple University
United States
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