Articles Related to tumor
Superficial CD34-Positive Fibroblastic Tumor: First Case Report from Latin-America and Review of the Literature
Superficial CD34-positive fibroblastic tumor is an infrequent soft-tissue tumor characterized by a lesion located in the subcutaneous fascia without affecting the soft or deep muscle planes. Its incidence is unknown; therefore, it represents a diagnostic challenge for both the surgical oncologist and pathologist. Given its high risk of local recurrence, extensive surgical resection is the recommended treatment modality. This is the first report of this rare entity in Latin-America.
Pseudotumor Cerebri Associated with Enteric Fever in a Child: A Case Report
Enteric fever is a common infection of tropical countries that can have a variety of neurological complications. Reported
neurological complications are encephalopathy, eningism, spastic paralysis-cerebral origin, convulsions, meningitis,
parkinsonian syndrome, sensory motor neuropathy, cerebellar involvement, and schizophrenic psychosis. The patient,
who was diagnosed with enteric fever and started treatment, developed headache and blurred vision 5 days after the
treatment. Cerebral venous sinus thrombosis secondary to enteric fever and related pseudotumor cerebri were detected
in the patient. When additional symptoms develop despite treatment in patients with enteric fever, complications such as
thrombosis and pseudotumor cerebri should be considered.
Malignant Scalp Tumors: Retrospective Analysis of 1000 Patients.
Background: Limited data on large cohort of patients with malignant tumors of the scalp are available in the literature. The
aim of this study was to review a large cohort of patients with malignant scalp tumors to determine epidemilogy, tumor
characteristics of this region and treatment.
Materials and Method: A retrospective review of patients with malignant scalp tumors diagnosed histopathologically
between 2005 and 2021 was performed. Demographic features and tumor characteristics were analyzed.
Results: A total of 1080 patients (M: F 3,5:1) were treated and followed up for a mean period of 42 months (12-120
months). Age at diagnosis ranged from 12 to 98 years. Most malignant scalp tumors (95,1%) occurred in those 50 years
or older and in bald patients (87%). Basal cell carcinomas (59,2%), squamous cell carcinomas (32,2%) and melanomas
were the most common histologic types. Incidence was highest on the frontal of temporal region (66,1%). Recurrence was
frequently in squamous and basal cell carcinomas but uncommon in melanoma.
Conclusions: Tumors of the scalp accounted about 8,01 % of all skin cancers. Tend to be basal and squamous cell carcinomas, many of which occur in the temporal and frontal region of bald men. The outlook for patients with scalp tumor is
positive, although we suggest excision margins of at least 3-4 mm and continued clinical vigilance is warranted given their
higher recurrence rates.
Therapy-related Myeloid Neoplasms after Pediatric Solid Cancer in a Single Reference Cancer Center in Brazil
Pediatric cancer overall survival has increased due to improvements in treatment. However, long-term adverse effects are a challenge for this population. Secondary myeloid neoplasm (MN) is one of the complications of solid tumor treatment. Therapy-related myeloid neoplasms (t-MN), therapy-related acute myeloid leukemia (t-AML), and therapy-related myelodysplastic syndrome (t-MDS) are the most common events. The aim of this study was to report a large pediatric sample and the relevance of t-MN after pediatric solid tumor therapy. We conducted a retrospective study between 2000-2016 in a cohort of pediatric patients treated for solid tumors who developed a secondary MN by medical records review and analysis. Seven from 2178 pediatric patients who were previously treated for solid tumors, were diagnosed with t-MN in a reference cancer center in Brazil. The median age at primary tumor diagnosis was 12.8 years old. Osteosarcoma, atypical primitive neuroectodermal tumor (PNET), Ewing sarcoma, and retinoblastoma were the most frequent solid tumors associated with t-MN. Three patients had a story of familiar cancer, and one patient with osteosarcoma had Li-Fraumeni syndrome confirmed. The median latency period to secondary MN was ten months and the prevalence rate was 0.32%. Two patients developed t-MDS and five, t-AML. All these patients received cytotoxic agents’ high doses that may have been associated with t-MN development. t-MN initial control, as well as unfavorable cytogenetic abnormalities, may have contributed to the poor outcome. We described the rarity of t-MN related to previous solid tumor therapy in a large pediatric sample in a Brazilian Cancer Center and their poor prognosis.
A Case Report of Peripheral Giant Cell Granuloma
Peripheral giant cell granuloma (PGCG) is a rarely seen benign lesion at soft oral tissue. In this report, the patient had a
history of central giant cell granuloma at the left mandibular posterior region. The lesion was excised two years ago. Patient
was consulted to our hospital for soft tissue growth at right maxillary anterior region. Excisional biopsy was planned and
the lesion was examined histopathologically. Giant cell reparative granuloma was described and routine examination was
advised to the patient
A Case Report of Diffuse Ischemic Injury from Leptomeningeal Midline Glioma Metastases
Diffuse midline gliomas with the histone 3-lysine-27-methionine (H3K27M) mutation should be considered in the differential diagnosis of recurrent hemiparesis and headache in patients with midline brainstem lesions, even with the absence of contrast-enhancement. Early diagnosis is essential for prognostication and engagement in trials evaluating novel therapeutics such as ONC-201.
Buschke-Lowenstein Tumor of the Vulva: A Case Report
Buschke-Lowenstein tumor or giant condyloma acuminata is a rare disorder of the external genitalia, belonging to the
group of verrucous carcinomas, and usually affects immunocompromised men. Human Papillomavirus (HPV) 6 and 11
are potentially involved in the pathophysiology. A detailed questioning, a rigorous clinical examination and complementary imaging are important to establish an accurate lesion assessment and an adapted management. Wide surgical excision
is the treatment of choice.
CNS Gliosis not Neoplasia in Kabuki Syndrome: A Case Report of a Brain ‘Tumor
An eight-year-old boy with Kabuki Syndrome (KS) and an enlarging CNS mass is presented. The ‘tumor’ was discovered incidentally
during MR imaging for a behavioral disorder and was located within the left globus pallidus. Retrospective review of previous MRIs
showed no abnormality in the basal ganglia seven years earlier but a small region (a few pixels) of increased in T2 signal intensity three
years earlier.
Cranial Vault Tumor Revealing Metastatic Thyroid Carcinoma
Distant metastases from follicular thyroid carcinoma are not uncommon, but bone localization in the cranial vault is extremely rare.
Although these metastases have a poor prognosis, early diagnosis and appropriate treatment can improve quality of life. We report a
case of follicular thyroid carcinoma revealed by a metastasis of the cranial vault initially diagnosed as meningioma.
Synchronous Contralateral Benign and Malignant Parotid Gland Tumors: Case Report
Multiple primary parotid gland tumors are rare, accounting for 1.7-5% of all parotid neoplasms, and the occurrence of bilateral parotid gland tumors is even lower (1.3-3.5%). These tumors can be synchronous or metachronous and the most common histologic type of bilateral parotid gland tumors is Warthin tumor (79.2-90%). Combined benign and malignant lesions and bilateral neoplasms of
different histologic types are even less frequently found.
After Brain Tumor Surgery: Catheter-Related Bacteremia of Chryseobacterium indologenes Development in Central Nervous System of An Infancy. A Case Report
40-day male infant has admitted to the hospital by family. He has a complaint including lack of suction, vomiting, decreased of movements and continuous sleep about a week of ongoing. Brain computed tomography recognized a mass (with hyperdense hemorrhage) in the posterior fossa and right cerebellar hemisphere.
Cost-Effectiveness and Budget Impact Analysis of Recombinant Tumor Necrosis Factor-Thymosin Alpha 1 in a Complex Treatment of Metastatic Breast Cancer
Recombinant tumor necrosis factor -thymosin alpha 1 (TNF-T) has been used in Russian oncological practice for a number of years.
Intracranial Inflammatory Pseudotumor: A Case Report and Review of the Literature
Inflammatory pseudotumors are lesions characterized by inflammatory cell infiltration and fibrosis. Central nervous system (CNS) inflammatory pseudotumors are much rarer, and generally manifest in the sellar and parasellar regions. We report a patient with an inflammatory pseudotumor in the temporal and occipital lobes treated in our department in 2017, and present a literature review. We discuss the etiology, imaging, pathology, and treatment of intracranial inflammatory pseudotumors.
A Clinical Case Study of Paratesticular Rhabdomyosarcoma of Young Adult
Para-testicular rhabdomyosarcoma (RPT) is a rare tumor of children and adolescents. The diagnosis is made by the anatomopathological study. The treatment must be multimodal and involves surgery, chemotherapy and radiotherapy. We report the case of a 19-year-old adolescent in our department for an embryonic-type para-testicular rhabdomyosarcoma. Our aim is to expose a rare and unknown case that may be life-threatening. We would like to emphasize on the fact that paratesticular rhabdomyosarcoma need to be brought
up in front of a tissular process expanding in the scrotum with normal testicules.
Granular Cell Tumor of the Tongue: 2 Cases Report and Review of the Literature
Granular cell tumor, also known as Abrikossoff tumor, is a rare lesion that arises from the nervous system. Most of these tumors are benign and only 1-2% are malignant. Although they can be found in any part of the human body, 45-65% appears in the head and neck region, mainly in the oral cavity. Here, we report 2 cases of granular cell tumor of the tongue, diagnosed by excisional biopsy. Until the present moment, both patients remain with no recurrence.
Editorial Board Members Related to tumor
Chunying Li
Assistant Professor
Department of Biochemistry and Molecular Biology
Wayne State University School of Medicine
United States
Department of Biochemistry and Molecular Biology
Wayne State University School of Medicine
United States
CHRISTOPHER THOMAS WHITLOW
Associate Professor of Division of Radiologic Sciences
Department of Radiology
Wake Forest School of Medicine
United States
Department of Radiology
Wake Forest School of Medicine
United States
Shengwen Calvin Li
Faculty Scientist
Center for Neuroscience and Stem Cell Research
University of California-Irvine School of Medicine
United States
Center for Neuroscience and Stem Cell Research
University of California-Irvine School of Medicine
United States
Hui Xiao
Associate Professor
Department of Pathology
Yeshiva University
United States
Department of Pathology
Yeshiva University
United States
Lan Zhou
Assistant Professor
Department of Pathology
Case Western Reserve University
United States
Department of Pathology
Case Western Reserve University
United States
Eugene S. Kim
Associate Professor
Department of Surgery
University of Southern California
United States
Department of Surgery
University of Southern California
United States
Ibrahim Fathy Nassar
Associate professor
Department of organic chemistry
Faculty of Specific Education
Ain Shams University
Egypt
Department of organic chemistry
Faculty of Specific Education
Ain Shams University
Egypt
Yaguang Xi
Assistant Professor
Mitchell Cancer Institute
University of South Alabama
United States
Mitchell Cancer Institute
University of South Alabama
United States
Rajkumar Vajpeyi
Assistant Professor
Laboratory Medicine and Pathobiology
University of Toronto
Canada
Laboratory Medicine and Pathobiology
University of Toronto
Canada
Huafeng Zhang
Professor
School of Life Science
University of Science & Technology of China
China
School of Life Science
University of Science & Technology of China
China