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Articles Related to tumorigenesis

Profile of Cytokines (IL-1β, TNF- α and IL-10) in Eyelid Tumors

Tissue cytokine levels (IL-1β, TNF-α and IL-10) have been utilized for screening, diagnosis, prognostication and treatment of tumors. The current study, therefore, purports to measure the levels of common cancer associated cytokines in histopathologically confirmed tissue samples of eyelid tumors.
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Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites

Ovarian cancer constitutes the second most common gynecological cancer with a five-year survival rate of 40%. Among the various histotypes associated with hereditary ovarian cancer, high-grade serous epithelial ovarian carcinoma (HGSEOC) is the most predominant and women with inherited mutations in BRCA1 have a lifetime risk of 40-60%. HGSEOC is a challenge for clinical oncologists, due to late presentation of patient, diagnosis and high rate of relapse. Ovarian tumors have a wide range of clinical presentations including development of ascites as a result of deregulated endothelial function thereby causing increased vascular permeability of peritoneal vessels.
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Editorial Board Members Related to tumorigenesis

Rodrigo Fernandez Valdivia

Assistant Professor
Department of Pathology
Wayne State University School of Medicine
United States

Huafeng Zhang

Professor
School of Life Science
University of Science & Technology of China
China

Dong-Hua Yang

Assistant Professor
Fox Chase Cancer Center
United States
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