Articles Related to virulence

The virulent Escherichia coli strains are responsible for extraintestinal infections. However, no past studies have been undertaken via the presence of virulence genes, ability of biofilms formation and the frequency of Escherichia coli pathovars recovered from different butcheries and slaughterhouses in Tunisia. The aims of this study was to investigate 1-) the prevalence of pathogenic E. coli strains isolated from bovine, ovine, and poultry meat in Tunisia, 2-) to determinate the antibiotic resistance profiles, and 3-) to determine their biofilm-forming ability by three phenotypic methods .Totally, 36 E. coli isolates from meat of healthy animals (bovines, ovine, and chickens) collected from different butcheries and slaughterhouses were investigated by searching by PCR genes encoding virulence factors (hlyA, stx1, stx2, fimH, papC, eaeAet papG allèle III, ibeA, iutA, and antibiotic susceptibility testing. Biofilm production was detected by three phenotypic: Congo Red Agar (CRA) method, tube method (TM) and tissue culture plate (TCP) method. In addition, the genetic relationship of isolates was determined by PFGE.

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Porphyromonas gingivalis (P. gingivalis) is a primary etiologic agent of generalized aggressive and chronic forms of periodontitis. It releases toxins called ‘gingipains’.Gingipains, (Arginine-and Lysine-specific cysteine proteinases) are proteases that are critical virulence factors in progression of periodontitis and degradation of cytokines expressed during inflammation. HRgpA and RgpB (products of two distinct but related genes) induce vascular permeability by activation of the kallikrein/kinin pathway and activating the blood coagulation system which in turn induces gingival crevicular fluid production and progression of inflammation leading to alveolar bone loss.

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Salmonella is a causative agent for a wide variety of pathological diseases in humans, cattle, poultry and other farm animals and hence Salmonella infections are a major cause of concern to humans, veterinary animals and to food industry.

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