Articles Related to Angiogenesis

Ovarian cancer constitutes the second most common gynecological cancer with a five-year survival rate of 40%. Among the various histotypes associated with hereditary ovarian cancer, high-grade serous epithelial ovarian carcinoma (HGSEOC) is the most predominant and women with inherited mutations in BRCA1 have a lifetime risk of 40-60%. HGSEOC is a challenge for clinical oncologists, due to late presentation of patient, diagnosis and high rate of relapse. Ovarian tumors have a wide range of clinical presentations including development of ascites as a result of deregulated endothelial function thereby causing increased vascular permeability of peritoneal vessels.

View complete article: PDF  |  Full-text

They are cytokines secreted by adipose tissue considered to be immunomodulating agents, however they can be more accurately put into the larger, growing list of adipose-derived hormones.

View complete article: PDF  |  Full-text  | Digital